| 骨质疏松与骨性关节炎关系的研究进展 |
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摘要点击次数: 1815
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投稿时间：2007-03-23
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| 期刊信息：《中国骨伤》2007年，第20卷，第12期，第876-878页 |
| DOI：doi:10.3969/j.issn.1003-0034.yyyy.nn.zzz |
| 基金项目: |
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| 中文摘要:骨质疏松(osteoporosis,OP)与骨关节炎(osteoarthritis,OA)是临床常见病多发病,骨质疏松症是以骨量减少、骨组织微细结构破坏导致骨骼脆性和骨折危险性增加为特征的一种系统性全身性骨骼疾病。而骨性关节炎是以软骨改变为主要特征,进而造成软骨下骨坏死,囊性变,骨密度增加和伴发骨赘形成的一种非特异性炎症。骨质疏松在骨关节炎发病过程中到底扮演什么角色,是否为骨关节炎的病因之一,国内外有大量文献对此进行了报道,其观点也不甚一致,目前存在3种:①OA与OP正相关,OP是OA的病因之一;②OA与OP负相关,OP不是OA的病因;③OA与OP不相关。通过查阅文献,笔者认为OP与OA不相关的可能性不大。本文就两者之间的正负关系作一综述,以期能对以后的临床工作有一定的指导作用。 |
| 【关键词】骨质疏松 骨关节炎 综述文献 |
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| Advance in association of osteoporosis and osteoarthritis |
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| ABSTRACT Both osteoporosis(OP) and osteoarthritis(OA) are common in clinic with a high morbidity.Osteoporosis is a systematic bone disease.Its characteristics include decrease in the bone mineral content,increase in bone fragility and increase in the risk of fracture resulting from damage on microstructure of bone.However,the feature of osteoarthritis is the change in the cartilage,resulting in a non-specific inflammation with sub chondral bone necrosis,cystis degeneration,increase in bone mineral density(BMD) and the osteophyte formation.The research on the role of the osteoporosis plays in the occurrence of osteoarthritis and whether it is one of the etiological factors of the osteoarthritis has been reported by a large amount of domestic and foreign articles.The viewpoints of those are not usually coincident,of which there are three main opinions:①OA and OP are in positive correlation,and OP is one of the etiological factors of OA;②OA and OP are in negative correlation,and OP is not the cause of OA;③No correlation between OA and OP.The author believes there is little possibility that OP has no correlation with OA.The positive or negative relationship between the two is reviewed in this article,expecting to direct clinical treatment afterwards. |
| KEY WORDS Osteoporosis Osteoarthritis Review literature |
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| 引用本文，请按以下格式著录参考文献： |
| 中文格式: | 伦学刚,谈志龙,白人骁.骨质疏松与骨性关节炎关系的研究进展[J].中国骨伤,2007,20(12):876~878 |
| 英文格式: | LUN Xue-gang,TAN Zhi-long,BAI Ren-xiao.Advance in association of osteoporosis and osteoarthritis[J].zhongguo gu shang / China J Orthop Trauma ,2007,20(12):876~878 |
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