| 脊髓Ⅱ号治疗大鼠脊髓损伤的病理组织学研究 |
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投稿时间：1997-09-21 修订日期：1998-03-01
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| 期刊信息：《中国骨伤》1998年，第11卷，第5期，第9-11页 |
| DOI：doi:10.3969/j.issn.1003-0034.yyyy.nn.zzz |
| 基金项目: |
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中文摘要:
目的: 观察脊髓Ⅱ号方剂对大鼠损伤脊髓神经元修复再生的影响。
方法: 制作18只T12 右半横断的Wistar大鼠模型,随机分为3组:脊髓Ⅱ号组、氢化可的松组、空白对照组,分别给予脊 髓Ⅱ号药液、激素、生理盐水。4周后取材,作神经病理组织学检查。
结果:脊髓Ⅱ号方剂具有明显疗 效,可以缩小损伤区域,抑制继发损伤,促进神经元胞体及神经纤维的修复再生。
结论:脊髓Ⅱ号方 剂可以促进损伤神经元的修复再生,具有良好的临床应用前景。 |
| 【关键词】脊髓Ⅱ号 脊髓损伤 脊髓修复再生 病理组织学 |
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| Pathohistological Study Of the Effect of SC-Ⅱ Decoction on Promoting Repair and Regeneration of In jured Spinal Cord |
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ABSTRACT
Aim To test and verify the therapeutic effect of Chinese herbs decoction "Spinal Cord Ⅱ (SC--Ⅱ)" on repair and regeneration of the spinal neurons.
Methods Experimental models of right hemitransection of spinal cord at T12 were made in 18 Wistar rats and divided randomly into three groups: treated with SC--Ⅱ decoction, hydrocortisone and normal saline respectively. Four weeks later, pathohistological examination was made.
Results There were obvious therapeutic effects of the SC--Ⅱ decoction: reducing the injured area, inhibiting the proliferation of connective tissue and neuroglia, promoting repair and regeneration of nerve fibers and the perikaryon in the hemitransected cord.
Conclusion There is a good prospect for clinical application of SC--Ⅱ decoction with the promotion of the repair of the injured spinal neurons. |
| KEY WORDS Chinese herbs SC--Ⅱ decoction Spinal cord injury repair and regeneration Pathohistological study |
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| 引用本文，请按以下格式著录参考文献： |
| 中文格式: | 韩凤岳,张凤绥,刘卫东.脊髓Ⅱ号治疗大鼠脊髓损伤的病理组织学研究[J].中国骨伤,1998,11(5):9~11 |
| 英文格式: | Han Fengyue,Zhang Fengsui,Liu Weidong.Pathohistological Study Of the Effect of SC-Ⅱ Decoction on Promoting Repair and Regeneration of In jured Spinal Cord[J].zhongguo gu shang / China J Orthop Trauma ,1998,11(5):9~11 |
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