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斜外侧椎间融合在Modic改变伴终板硬化腰椎间盘退变治疗中的应用
Hits: 1907   Download times: 554   Received:April 11, 2022    
作者Author单位UnitE-Mail
陈平泉 CHEN Ping-quan 嘉兴市中医医院骨伤科, 浙江 嘉兴 314001 Department of Orthopaedics, Jiaxing TCM Hospital, Jiaxing 314001, Zhejing, China  
曾忠友 ZENG Zhong-you 武警部队骨科医学中心 武警海警总队医院骨二科, 浙江 嘉兴 314000 The Second Department of Orthopaedics, Armed Police Marine Police Corps Hospital, Orthopedic Medical Center of Armed Police Force, Jiaxing 314000, Zhejiang, China zjzengzy@126.com 
赵兴 ZHAO Xing 浙江大学医学院附属邵逸夫医院骨科, 浙江 杭州 310016 Department of Orthopaedics, Run Run Show Hospital Affiliated to Zhejiang University Medical School, Hangzhou 310016, Zhejiang, China  
范时洋 FAN Shi-yang 武警部队骨科医学中心 武警海警总队医院骨二科, 浙江 嘉兴 314000 The Second Department of Orthopaedics, Armed Police Marine Police Corps Hospital, Orthopedic Medical Center of Armed Police Force, Jiaxing 314000, Zhejiang, China  
吴宏飞 WU Hong-fei 武警部队骨科医学中心 武警海警总队医院骨二科, 浙江 嘉兴 314000 The Second Department of Orthopaedics, Armed Police Marine Police Corps Hospital, Orthopedic Medical Center of Armed Police Force, Jiaxing 314000, Zhejiang, China  
俞伟 YU Wei 武警部队骨科医学中心 武警海警总队医院骨二科, 浙江 嘉兴 314000 The Second Department of Orthopaedics, Armed Police Marine Police Corps Hospital, Orthopedic Medical Center of Armed Police Force, Jiaxing 314000, Zhejiang, China  
张建乔 ZHANG Jian-qiao 嘉兴市中医医院骨伤科, 浙江 嘉兴 314001 Department of Orthopaedics, Jiaxing TCM Hospital, Jiaxing 314001, Zhejing, China  
宋永兴 SONG Yong-xing 武警部队骨科医学中心 武警海警总队医院骨二科, 浙江 嘉兴 314000 The Second Department of Orthopaedics, Armed Police Marine Police Corps Hospital, Orthopedic Medical Center of Armed Police Force, Jiaxing 314000, Zhejiang, China  
范顺武 FAN Shun-wu 浙江大学医学院附属邵逸夫医院骨科, 浙江 杭州 310016 Department of Orthopaedics, Run Run Show Hospital Affiliated to Zhejiang University Medical School, Hangzhou 310016, Zhejiang, China  
方向前 FANG Xiang-qian 浙江大学医学院附属邵逸夫医院骨科, 浙江 杭州 310016 Department of Orthopaedics, Run Run Show Hospital Affiliated to Zhejiang University Medical School, Hangzhou 310016, Zhejiang, China  
裴斐 PEI Fei 武警部队骨科医学中心 武警海警总队医院骨二科, 浙江 嘉兴 314000 The Second Department of Orthopaedics, Armed Police Marine Police Corps Hospital, Orthopedic Medical Center of Armed Police Force, Jiaxing 314000, Zhejiang, China  
宋国浩 SONG Guo-hao 武警部队骨科医学中心 武警海警总队医院骨二科, 浙江 嘉兴 314000 The Second Department of Orthopaedics, Armed Police Marine Police Corps Hospital, Orthopedic Medical Center of Armed Police Force, Jiaxing 314000, Zhejiang, China  
期刊信息:《中国骨伤》2023年36卷,第1期,第29-37页
DOI:10.12200/j.issn.1003-0034.2023.01.006
基金项目:浙江省医药卫生科技计划项目(编号:2020KY968)


目的:探讨Stand-alone斜外侧椎间融合(oblique lateral interbody fusion,OLIF)应用于Modic改变伴终板硬化的腰椎间盘退变治疗的可行性和临床效果。

方法:回顾性分析2015年1月至2018年12月3家医疗中心收治的16例Modic改变伴终板硬化的腰椎间盘退变患者。其中男6例,女10例;年龄45~67(55.48±8.07)岁;病史36~240(82.40±47.68)个月。病变部位:L2,3 2例,L3,4 5例,L4,5 9例;均表现为慢性腰痛,伴下肢神经症状3例。采用单纯斜外侧腰椎椎间融合术治疗,术后对临床和影像学结果,以及并发症情况进行观察。

结果:术中无血管、终板损伤和椎体骨折。切口长度(4.06±0.42) cm,手术时间(45.12±5.43) min,术中出血量(33.40±7.29) ml;术后72 h切口疼痛视觉模拟评分(visual analogue scale,VAS)为1.14±0.47。所有患者无切口皮肤坏死、愈合不良或感染;出现交感链损伤1例、左大腿前外侧疼痛并麻木2例、左侧髂腰肌无力1例,均为一过性损伤,并发症发生率为25%(4/16)。16例患者均获得随访,时间12~36(20.80±5.46)个月。术后椎间隙高度获得明显的恢复,随访过程中有轻度丢失。末次随访时腰椎冠状面和矢状面平衡均获得良好的改善。融合器无明显沉降或移位,均获得椎间融合。末次随访时日本骨科协会(Japanese Orthop- aedic Association,JOA)评分和Oswestry 功能障碍指数(Oswestry disability index,ODI)明显改善。

结论:只要严格病例选择,充分的术前检查,采用Stand-alone OLIF治疗Modic改变伴终板硬化的腰椎间盘退变效果良好,临床优势明显,是较好的手术选择。
[关键词]:腰椎间盘退变  Modic改变  终板硬化  脊柱融合术  并发症
 
Application of oblique lateral interbody fusion in the treatment of lumbar intervertebral disc degeneration in patients with Modic change and endplate sclerosis
Abstract:

Objective To explore the feasibility and clinical effect of Stand-alone oblique lateral interbody fusion (OLIF) in the treatment of lumbar intervertebral disc degeneration with Modic changes and endplate sclerosis.

Methods A retrospective analysis was performed on 16 cases with lumbar intervertebral disc degeneration with Modic changes and endplate sclerosis admitted to three medical centers from January 2015 to December 2018. There were 6 males and 10 females,the age ranged from 45 to 67 years old with an average of (55.48±8.07) years old,the medical history ranged from 36 to 240 months with an average of (82.40±47.68) months. The lesion sites included L2,3 in 2 cases,L3,4 in 5 cases,and L4,5 in 9 cases. All patients presented with chronic low back pain with lower limb neurological symptoms in 3 cases. All patients were treated by Stand-alone oblique lateral lumbar interbody fusion. Clinical and radiological findings and complications were observed.

Results There was no vascular injury,endplate injury and vertebral fracture during the operation. The mean incision length,operation time,and intraoperative blood loss were(4.06±0.42) cm,(45.12±5.43) min,(33.40±7.29) ml,respectively. The mean visual analogue scale (VAS) of the incision pain was (1.14±0.47) at 72 hours after operation. There was no incision skin necrosis,poor incision healing or infection in patients. Sympathetic chain injury occurred in 1 case,anterolateral pain and numbness of the left thigh in 2 cases,and weakness of the left iliopsoas muscle in 1 case,all of which were transient injuries with a complication rate of 25%(4/16). All 16 patients were followed up from 12 to 36 months with an average of (20.80±5.46) months. The intervertebral space height was significantly recovered after operation,with slight lost during the follow-up. Coronal and sagittal balance of the lumbar spine showed good improvement at the final follow-up. There was no obvious subsidence or displacement of the cage,and the interbody fusion was obtained. At the final follow-up,Japanese Orthopaedic Association(JOA) score and Oswestry disability index(ODI) were significantly improved.

Conclusion As long as the selection of case is strict enough and the preoperative examination is sufficients,the use of Stand-alone OLIF in the treatment of lumbar intervertebral disc degeneration with Modic changes and endplate sclerosis has a good results,with obvious clinical advantages and is a better surgical choice.
KEYWORDS:Lumbar disc degeneration  Modic changes  Endplate sclerosis  Spinal fusion  Complications
 
引用本文,请按以下格式著录参考文献:
中文格式:陈平泉,曾忠友,赵兴,范时洋,吴宏飞,俞伟,张建乔,宋永兴,范顺武,方向前,裴斐,宋国浩.斜外侧椎间融合在Modic改变伴终板硬化腰椎间盘退变治疗中的应用[J].中国骨伤,2023,36(1):29~37
英文格式:CHEN Ping-quan,ZENG Zhong-you,ZHAO Xing,FAN Shi-yang,WU Hong-fei,YU Wei,ZHANG Jian-qiao,SONG Yong-xing,FAN Shun-wu,FANG Xiang-qian,PEI Fei,SONG Guo-hao.Application of oblique lateral interbody fusion in the treatment of lumbar intervertebral disc degeneration in patients with Modic change and endplate sclerosis[J].zhongguo gu shang / China J Orthop Trauma ,2023,36(1):29~37
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