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可吸收止血流体明胶在颈前路椎体次全切除减压融合术中的应用
Hits: 2688   Download times: 1233   Received:May 20, 2019    
作者Author单位UnitE-Mail
刘猛 LIU Meng 徐州医科大学研究生学院, 江苏 徐州 221000  
辛兵 XIN Bing 徐州医科大学附属医院脊柱外科, 江苏 徐州 221000 Department of Spine Surgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000, Jiangsu, China 18052268323@189.cn 
刘永涛 LIU Yong-tao 徐州医科大学附属医院脊柱外科, 江苏 徐州 221000 Department of Spine Surgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000, Jiangsu, China  
黄栋 HUANG Dong 徐州医科大学附属医院脊柱外科, 江苏 徐州 221000 Department of Spine Surgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000, Jiangsu, China  
李宁 LI Ning 徐州医科大学研究生学院, 江苏 徐州 221000  
期刊信息:《中国骨伤》2020年33卷,第1期,第53-58页
DOI:10.3969/j.issn.1003-0034.2020.01.010


目的:探究可吸收止血流体明胶在单节段颈前路椎体次全切除减压融合术(anterior discectomy fusion,ACCF)中的止血效果。

方法:自2014年8月至2018年2月选取行单节段颈前路椎体次全切除减压融合术患者44例,分为两组:试验组22例,男10例,女12例,年龄(55.6±9.7)岁,术中用可吸收止血流体明胶止血;对照组22例,男11例,女11例,年龄(54.4±11.1)岁,术中采用传统止血方法止血。比较两组手术时间、椎管减压所需时间、术中出血量、术后负压引流量、术后神经功能改善率、术后骨融合时间、术后钛网沉降率、术后血肿发生以及其他术后不良事件并发症。

结果:试验组手术时间(83.1±19.2) min,明显少于对照组的(89.5±17.0) min(P<0.05);两组椎管减压时间分别为(52.4±13.7)、(56.1±14.6) min,差异有统计学意义(P=0.001);两组术中出血量分别为(49.9±12.4)、(90.6±36.7) ml,差异有统计学意义(P<0.05);两组术后负压引流球内引流总量分别为(42.5±18.3)、(60.0±22.8) ml,差异有统计学意义(P<0.05);两组术后1周神经功能改善率差异无统计学意义,术后3、6个月试验组比对照组有更好神经功能改善率。两组术后6个月均获得骨性融合,术后3个月均未发现明显钛网沉降,均无出现急性血肿、脑脊液漏及其他术后并发症。

结论:可吸收止血流体明胶在ACCF手术中止血效果显著,可保持良好的手术术野,可减少椎管减压时间,减少术中出血量术后引流量,是一种较传统止血方法更有效且安全的止血材料。
[关键词]:明胶海绵,吸收性  止血  减压  脊柱融合术  颈椎病
 
Application of absorbable hemostatic fluid gelatin in anterior cervical subtotal vertebral resection and fusion
Abstract:

Objective: To explore the hemostatic effect of absorbable hemostatic fluid gelatin in single anterior cervical subtotal corpectomy and decompression fusion(ACCF).

Methods: From August 2014 to February 2018,44 patients with single anterior cervical corpectomy decompression and fusion were selected and divided into two groups:22 cases in experimental group including 10 males and 12 females with an average age of (55.6±9.7) years old,were treated by hemostasis with absorbable hemostasis fluid gelatin;22 cases in control group including 11 males and 11 females with an average age of (54.4±11.1) years old were treated by hemostasis with traditional hemostasis method. The operation time,decompression time,intraoperative hemorrhage,postoperative negative pressure drainage,postoperative neurological improvement rate(JOA%),postoperative bone fusion time,postoperative titanium mesh subsidence rate,postoperative hematoma and other postoperative complications were compared between the two groups.

Results: The operative time of the experimental group(83.1±19.2) min was significantly shorter than that of the control group (89.5±17.0) min (P<0.05);the decompression time of the spinal canal in the two groups was(52.4±13.7),(56.1±14.6) min,with a statistically significant difference (P=0.001);the amount of bleeding in the two groups was(49.9±12.4),(90.6±36.7) ml,with a statistically significant difference(P<0.05);the total amount of drainage in the negative pressure drainage ball after operation in the two groups was (42.5±18.3),(60.0±22.8) ml,the difference was statistically significant(P<0.05). There was no statistically significant difference in the improvement rate of nerve function between the two groups at 1 week after operation,and the improvement rate of nerve function in the experimental group was better than that in the control group at 3 and 6 months after operation. In the two groups,bone fusion was obtained 6 months after operation,no obvious titanium mesh subsidence was found in 3 months after operation,no acute hematoma,CSF leakage and other postoperative complications were found.

Conclusion: Absorbable hemostatic fluid gelatin has a significant hemostatic effect in ACCF operation,can maintain a good operation field,can reduce the decompression time of spinal canal,reduce the amount of bleeding during operation and the amount of bleeding after operation. It is a more effective and safe hemostatic material than the traditional hemostatic method.
KEYWORDS:Gelatin sponge,absorbable  Hemostasis  Decompression  Spinal fusion  Cervical spondylosis
 
引用本文,请按以下格式著录参考文献:
中文格式:刘猛,辛兵,刘永涛,黄栋,李宁.可吸收止血流体明胶在颈前路椎体次全切除减压融合术中的应用[J].中国骨伤,2020,33(1):53~58
英文格式:LIU Meng,XIN Bing,LIU Yong-tao,HUANG Dong,LI Ning.Application of absorbable hemostatic fluid gelatin in anterior cervical subtotal vertebral resection and fusion[J].zhongguo gu shang / China J Orthop Trauma ,2020,33(1):53~58
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