| 祛腐生肌膏促进感染性创面愈合的临床观察 |
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Received:May 18, 2019
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| 作者 | Author | 单位 | Unit | E-Mail |
| 张磊 |
ZHANG Lei |
南京中医药大学, 江苏 南京 210000
徐州市中医院, 江苏 徐州 221000 |
Xuzhou Hospital of Traditional Chinese Medicine, Xuzhou 221000, Jiangsu, China |
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| 李朝顶 |
LI Chao-ding |
徐州市中医院, 江苏 徐州 221000 |
Xuzhou Hospital of Traditional Chinese Medicine, Xuzhou 221000, Jiangsu, China |
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| 沈金虎 |
SHEN Jin-hu |
徐州市中医院, 江苏 徐州 221000 |
Xuzhou Hospital of Traditional Chinese Medicine, Xuzhou 221000, Jiangsu, China |
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| 杨六中 |
YANG Liu-zhong |
徐州市中医院, 江苏 徐州 221000 |
Xuzhou Hospital of Traditional Chinese Medicine, Xuzhou 221000, Jiangsu, China |
zolopec927@163.com |
| 王建伟 |
WANG Jian-wei |
南京中医药大学, 江苏 南京 210000 |
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| 张镇 |
ZHANG Zhen |
徐州市中医院, 江苏 徐州 221000 |
Xuzhou Hospital of Traditional Chinese Medicine, Xuzhou 221000, Jiangsu, China |
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| 罗仲伟 |
LUO Zhong-wei |
徐州市中医院, 江苏 徐州 221000 |
Xuzhou Hospital of Traditional Chinese Medicine, Xuzhou 221000, Jiangsu, China |
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| 程飞 |
CHENG Fei |
徐州市中医院, 江苏 徐州 221000 |
Xuzhou Hospital of Traditional Chinese Medicine, Xuzhou 221000, Jiangsu, China |
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| 期刊信息：《中国骨伤》2019年32卷，第12期，第1144-1147页 |
| DOI：10.3969/j.issn.1003-0034.2019.12.015 |
| 基金项目:江苏省中医药局科技项目（编号：YB201828） |
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目的：探讨祛腐生肌膏促进创伤后感染性创面愈合的临床疗效。
方法：2014年1月至2018年6月收治暴力外伤致软组织损伤、皮肤缺损伴创面感染60例患者，其中男32例，女28例；年龄18~65岁，平均41.3岁。其中30例行祛腐生肌膏换药治疗（祛腐生肌膏组），30例行常规生理盐水碘伏换药治疗（对照组）。比较两组患者的创面面积减小率、腐肉脱落天数、新生上皮出现时间、换药28 d痊愈率。
结果：祛腐生肌膏组患者使用大剂量祛腐生肌膏后，创面脓液增多，肉芽随之新生，创面边缘出现新生上皮，呈现迅速愈合的现象。祛腐生肌膏组患者各个时相点创面愈合率均高于对照组，祛腐生肌膏组患者的腐肉脱落时间和新生上皮出现时间均早于对照组。祛腐生肌膏组换药28 d的痊愈率高于对照组（P<0.05）。所有患者治疗后获随访，时间6~12个月，平均9.4个月，骨与肌腱的外露区域最终得以良好覆盖。两组患者治疗过程中生命体征平稳，无不良反应发生。
结论：祛腐生肌膏能促进肉芽组织生长，促进新生皮肤产生，加快创伤后感染性创面的愈合。 |
| [关键词]:病灶感染 中药疗法 肉芽组织 外治法 |
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| Effect of Qufu Shengji ointment(祛腐生肌膏) on promoting the healing of infectious wounds |
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Abstract:
Objective: To explore the clinical effect of Qufu Shengji ointment(祛腐生肌膏,QFSJO) in promoting the wound healing after trauma.
Methods: From January 2014 to June 2018,60 patients with soft tissue injury,skin defect and wound infection caused by violent trauma were admitted,including 32 males and 28 females,aged from 18 to 65 years,with an average age of 41.3 years. Among them,30 patients were treated with QFSJO (QFSJO group) and 30 patients were treated with normal saline iodophor (control group). The reduction rate of wound area,the days of decayed flesh,the time of new epithelium and the recovery rate of 28 days after dressing change were compared between the two groups.
Results: In the QFSJO group,after using large dose of QFSJO,the pus of the wound increased,the granulation grew,and the new epithelium appeared on the edge of the wound,showing a rapid healing phenomenon. The wound healing rate of QFSJO group was higher than that of the control group at all time points,and the time of decaying flesh and new epithelium appeared in QFSJO group was earlier than that of the control group. The recovery rate of QFSJO group was significantly higher than that of the control group(P<0.05). All the patients were followed up,and the duration ranged form 6 to 12 months,with an average of 9.4 months. The exposed areas of bone and teadon were covered well. The vital signs of the two groups were stable and no adverse reactions occurred.
Conclusion: QFSJO can promote the growth of granulation tissue,promote the production of new skin,and accelerate the healing of infectious wound after trauma. |
| KEYWORDS:Focal infection Herbal therapy Granulation tissue External therapy |
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| 引用本文，请按以下格式著录参考文献： |
| 中文格式: | 张磊,李朝顶,沈金虎,杨六中,王建伟,张镇,罗仲伟,程飞.祛腐生肌膏促进感染性创面愈合的临床观察[J].中国骨伤,2019,32(12):1144~1147 |
| 英文格式: | ZHANG Lei,LI Chao-ding,SHEN Jin-hu,YANG Liu-zhong,WANG Jian-wei,ZHANG Zhen,LUO Zhong-wei,CHENG Fei.Effect of Qufu Shengji ointment(祛腐生肌膏) on promoting the healing of infectious wounds[J].zhongguo gu shang / China J Orthop Trauma ,2019,32(12):1144~1147 |
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