Sponsor
  • ·
  • Chinese Association of
    Integrative Medicine;
    China Academy of Chinese
    Medicine Sciences
Editing
  • ·
  • Editorial Board of
    China Journal of
    Orthopaedics and Traumatology
Publishing
  • ·
  • Publishing House,
    China Journal of
    Orthopaedics and Traumatology
Overseas Distributor
  • ·
  • China International Book
    Trading Corporation
    P.O.Box 399,Beijing,China
    Code No.M587
Mail-order
  • ·
  • Publishing House,
    China Journal of
    Orthopaedics and Traumatology
    No.16A, Nanxiaojie, Dongzhimennei,
    Beijing 100700,China
    Tel:0086-10-84020925
    Fax:0086-10-84036581
    Http://www.zggszz.com
    E-mail:zggszz@sina.com
人工关节置换术后假体周围感染与术前贫血的研究进展
Hits: 1574   Download times: 1246   Received:June 25, 2017    
作者Author单位UnitE-Mail
王伟 WANG Wei 兰州军区兰州总医院全军骨科中心关节外科, 甘肃 兰州 730050 Department of Joint Surgery, Orthopaedics Center of PLA, Lanzhou General Hospital of Lanzhou Military Region, Lanzhou 730050, Gansu, China  
刘军 LIU Jun 兰州军区兰州总医院全军骨科中心关节外科, 甘肃 兰州 730050 Department of Joint Surgery, Orthopaedics Center of PLA, Lanzhou General Hospital of Lanzhou Military Region, Lanzhou 730050, Gansu, China  
周胜虎 ZHOU Sheng-hu 兰州军区兰州总医院全军骨科中心关节外科, 甘肃 兰州 730050 Department of Joint Surgery, Orthopaedics Center of PLA, Lanzhou General Hospital of Lanzhou Military Region, Lanzhou 730050, Gansu, China  
李生贵 LI Sheng-gui 兰州军区兰州总医院全军骨科中心关节外科, 甘肃 兰州 730050 Department of Joint Surgery, Orthopaedics Center of PLA, Lanzhou General Hospital of Lanzhou Military Region, Lanzhou 730050, Gansu, China  
乔永杰 QIAO Yong-Jie 兰州军区兰州总医院全军骨科中心关节外科, 甘肃 兰州 730050 Department of Joint Surgery, Orthopaedics Center of PLA, Lanzhou General Hospital of Lanzhou Military Region, Lanzhou 730050, Gansu, China  
刘建 LIU Jian 兰州军区兰州总医院全军骨科中心关节外科, 甘肃 兰州 730050 Department of Joint Surgery, Orthopaedics Center of PLA, Lanzhou General Hospital of Lanzhou Military Region, Lanzhou 730050, Gansu, China  
甄平 ZHEN Ping 兰州军区兰州总医院全军骨科中心关节外科, 甘肃 兰州 730050 Department of Joint Surgery, Orthopaedics Center of PLA, Lanzhou General Hospital of Lanzhou Military Region, Lanzhou 730050, Gansu, China zhenpingok@163.com 
期刊信息:《中国骨伤》2018年31卷,第10期,第971-975页
DOI:10.3969/j.issn.1003-0034.2018.10.019
基金项目:国家自然科学基金(编号:81371983);甘肃省科技支撑计划(编号:S04671);甘肃省青年科技基金(编号:1606RJYA300)
假体周围感染是人工关节置换术后最严重的并发症。流行病学调查发现,围术期贫血是造成假体周围感染的独立危险因素,其可通过影响细胞机制及自身免疫功能等多个方面发挥重要影响。既往国内外诸多学者对假体周围感染与术后贫血的关系进行研究,但对假体周围感染与术前贫血的相关性探讨较少。术前贫血可使红细胞表面的C3b受体减少,机体免疫功能降低,血源性感染增加,术后康复时间延长,进而诱发假体周围感染。故对于术前合并贫血的患者,除预防性使用抗生素外,术前应补充铁剂、配合促红细胞生成素积极纠正贫血、治疗影响血红蛋白生成的慢性并发症、提高患者自身的免疫状况、对符合输血指征的患者进行相应的输血治疗,从而更好地预防人工关节置换术后假体周围感染的发生,减少二次或多次翻修的概率。
[关键词]:关节成形术,置换  假体相关感染  贫血  综述文献
 
Periprosthetic joint infection after artificial joint replacement and preoperative anemia
Abstract:Periprosthetic joint infection is the most serious complication after artificial joint arthroplasty. Epidemiological investigation has indicated that perioperative anemia is an independent risk factor for periprosthetic joint infection,which could play an important role by suppressing cellular mechanisms and autoimmune functions. Many domestic and overseas scholars have studied the relationship between periprosthetic joint infection and postoperative anemia,but the relationship between preoperative anemia and periprosthetic joint infection is relatively rare. However,preoperative anemia can reduce the C3b receptor on surface of red blood cells,decrease immune function of the body,increase blood-borne infection,prolong postoperative rehabilitation time,and lead to periprosthetic joint infection. For patients with preoperative anemia,prophylactic antibiotics could be used to prevent. And complement chalybeate used before operation,correct anemia by hemopoietin,treat chronic complications influence by hemoglobin production and improve patient's own immune status,blood transfusion treatment for patients with blood transfusion indications are performed. It could be better prevent occurrence of periprosthetic joint infection after total joint arthroplasty,and reducing chance of secondary or multiple renovations.
KEYWORDS:Arthroplasty,replacement  Prosthesis-related infections  Anemia  Review literature
 
引用本文,请按以下格式著录参考文献:
中文格式:王伟,刘军,周胜虎,李生贵,乔永杰,刘建,甄平.人工关节置换术后假体周围感染与术前贫血的研究进展[J].中国骨伤,2018,31(10):971~975
英文格式:WANG Wei,LIU Jun,ZHOU Sheng-hu,LI Sheng-gui,QIAO Yong-Jie,LIU Jian,ZHEN Ping.Periprosthetic joint infection after artificial joint replacement and preoperative anemia[J].zhongguo gu shang / China J Orthop Trauma ,2018,31(10):971~975
View Full Text  View/Add Comment  Download reader
Close




版权所有:Editorial Office of China Journal of Orthopaedics and Traumatology京ICP备12048066号  版权声明
地址:No.16A, Nanxiaojie, Dongzhimennei, Beijing 100700, China
电话:0086-10-84036581 传真:0086-10-84036581 Email:zggszz@sina.com