| 痛风石诊断与治疗的研究进展 |
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Received:October 13, 2016
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| 作者 | Author | 单位 | Unit | E-Mail |
| 冉兵 |
RAN Bing |
赣南医学院第一附属医院疼痛科, 江西 赣州 341000 |
Department of Pain, the First Affiliated Hospital of Gannan Medical Unversity, Ganzhou 341000, Jiangxi, China |
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| 魏俊 |
WEI Jun |
赣南医学院第一附属医院疼痛科, 江西 赣州 341000 |
Department of Pain, the First Affiliated Hospital of Gannan Medical Unversity, Ganzhou 341000, Jiangxi, China |
weijun5812@163.com |
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| 期刊信息：《中国骨伤》2017年30卷，第9期，第876-880页 |
| DOI：10.3969/j.issn.1003-0034.2017.09.019 |
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| 痛风石由尿酸及尿酸盐晶体沉积于外周骨及软组织而形成，常发生于四肢关节及皮下，其不仅影响局部外观还可破坏骨与关节结构，影响肢体的正常功能。传统经典药物治疗是控制高尿酸血症的必要措施，然而对于晚期痛风石，药物难以有效，手术治疗可清除痛风石，控制机体尿酸总量，改善局部功能，但其创伤较大且易复发。新型抗尿酸药物是目前研究热点，其除了对于控制血尿酸水平疗效显着外尚可溶解部分痛风石，但其费用较高。晚期痛风石最佳治疗方法目前仍存在争议。 |
| [关键词]:痛风石 诊断 外科手术 尿酸酶 |
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| Progress on diagnosis and treatment of tophus |
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| Abstract:Tophi deposit in the peripheral bone joints or soft tissues are formed by uric acid and urate crystal. It does not only affect local appearance but also destroy the bone and joint structure,resulting in loss of function. Traditional medical treatment is an effective way to control the hyperuricemia,but it is ineffective to tophus. Surgery is a relatively effective method for the treatment of tophus. It can successfully reduces the content of uric acid in the body and improves the limbs function,but it causes surgical trauma and complications. As new medicine,Urcase is a hot spot in the present study. It can not only control the blood uric acid level but also dissolve part of tophus. But the cost is higher than traditional medicines. There is still dispute in treatment for advanced tophus. |
| KEYWORDS:Tophus Diagnosis Surgical procedures,operative Uricase |
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| 引用本文，请按以下格式著录参考文献： |
| 中文格式: | 冉兵,魏俊.痛风石诊断与治疗的研究进展[J].中国骨伤,2017,30(9):876~880 |
| 英文格式: | RAN Bing,WEI Jun.Progress on diagnosis and treatment of tophus[J].zhongguo gu shang / China J Orthop Trauma ,2017,30(9):876~880 |
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