| 多发骨质疏松椎体压缩骨折的相关因素研究 |
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Received:May 08, 2016
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| 作者 | Author | 单位 | Unit | E-Mail |
| 林顺鑫 |
LIN Shun-xin |
广州中医药大学, 广东 广州 510405 |
Department of Spinal Orthopaedics, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, Guangdong, China |
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| 江晓兵 |
JIANG Xiao-bing |
广州中医药大学第一附属医院脊柱骨科, 广东 广州 510405 |
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| 沈耿杨 |
SHEN Geng-yang |
广州中医药大学, 广东 广州 510405 |
Department of Spinal Orthopaedics, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, Guangdong, China |
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| 莫凌 |
MO Ling |
广州中医药大学第一附属医院脊柱骨科, 广东 广州 510405 |
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| 任辉 |
REN Hui |
广州中医药大学, 广东 广州 510405 |
Department of Spinal Orthopaedics, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, Guangdong, China |
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| 崔健超 |
CUI Jian-chao |
广州中医药大学第一附属医院脊柱骨科, 广东 广州 510405 |
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| 梁德 |
LIANG De |
广州中医药大学第一附属医院脊柱骨科, 广东 广州 510405 |
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7319890789@qq.com |
| 杨志东 |
YANG Zhi-dong |
广州中医药大学第一附属医院脊柱骨科, 广东 广州 510405 |
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| 张顺聪 |
ZHANG Shun-cong |
广州中医药大学第一附属医院脊柱骨科, 广东 广州 510405 |
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| 张志达 |
ZHANG Zhi-da |
广州中医药大学, 广东 广州 510405 |
Department of Spinal Orthopaedics, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, Guangdong, China |
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| 期刊信息：《中国骨伤》2016年29卷，第9期，第836-840页 |
| DOI：10.3969/j.issn.1003-0034.2016.09.013 |
| 基金项目:广东省自然科学基金（编号：2014A030310082）；广东省中医药科学院联合科研项目（编号：2014A020221021） |
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目的：探讨发生多发骨质疏松椎体压缩骨折的相关因素。
方法：回顾性分析2011年3月至2015年3月收治的199例骨质疏松性椎体压缩骨折患者病史及影像学资料，根据骨折椎体的数量分为单椎体骨折组与多椎体骨折组，采用非条件 Logistic 回归分析可能影响发生多椎体骨折的危险因素。
结果：多椎体骨折组（71例）与单椎体骨折组（128例）的年龄、性别、体重质量指数（BMI）、既往高血压、糖尿病史差异均无统计学意义，而两组骨密度T值与脊柱畸形指数差异有统计学意义，多椎体骨折组骨密度较单椎体骨折组降低，而SDI评分高于单椎体骨折组。非条件Logistic回归分析发现脊柱畸形指数与多椎体骨折明显相关，其中脊柱畸形指数[2≤脊柱畸形指数<4，OR=2.587，95% CI（1.148，5.828）；脊柱畸形指数≥-4，OR=7.775，95% CI（3.272，18.478）]及骨密度T值<-4.5SD，OR=2.608，95% CI（1.038，6.551）]差异有统计学意义。
结论：骨密度越低，脊柱畸形指数评分越高，发生多椎体骨折的危险性越高。 |
| [关键词]:骨质疏松 脊柱骨折 骨密度 危险因素 |
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| Risk factors for multiple-level osteoporosis vertebral compression fractures |
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Abstract:
Objective: To identify risk factors associated with patients suffered multiple-level osteoporosis vertebral compression fractures(OVCFs).
Methods: From March 2011 to March 2015,199 patients suffered osteoporotic were classified into multiple-level OVCFs group and single level OVCF group. Multivariate logistic regression analysis were performed to identify risks factors associated with multiple-level OVCFs.
Results: All the patients underwent OVCF,including 71 multiple-level OVCFs and 128 single level OVCF. There were no differences in the age,gender,BMI,hypertension and diabetes between two groups. While multiple-level OVCFs were associated with spinal deformity index SDI[(2≤SDI<4,OR=2.587,95% CI(1.148,5.828);SDI≥-4,OR=7.775,95% CI(3.272,18.478)],BMD[(T<-4.5SD,OR=2.608,95% CI(1.038,6.551)].
Conclusion: SDI and BMD might be the risk factors for multiple-level OVCFs. |
| KEYWORDS:Osteoporosis Spinal fractures Bone density Risk factors |
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| 引用本文，请按以下格式著录参考文献： |
| 中文格式: | 林顺鑫,江晓兵,沈耿杨,莫凌,任辉,崔健超,梁德,杨志东,张顺聪,张志达.多发骨质疏松椎体压缩骨折的相关因素研究[J].中国骨伤,2016,29(9):836~840 |
| 英文格式: | LIN Shun-xin,JIANG Xiao-bing,SHEN Geng-yang,MO Ling,REN Hui,CUI Jian-chao,LIANG De,YANG Zhi-dong,ZHANG Shun-cong,ZHANG Zhi-da.Risk factors for multiple-level osteoporosis vertebral compression fractures[J].zhongguo gu shang / China J Orthop Trauma ,2016,29(9):836~840 |
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