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多发骨质疏松椎体压缩骨折的相关因素研究
Hits: 1905   Download times: 432   Received:May 08, 2016    
作者Author单位UnitE-Mail
林顺鑫 LIN Shun-xin 广州中医药大学, 广东 广州 510405 Department of Spinal Orthopaedics, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, Guangdong, China  
江晓兵 JIANG Xiao-bing 广州中医药大学第一附属医院脊柱骨科, 广东 广州 510405  
沈耿杨 SHEN Geng-yang 广州中医药大学, 广东 广州 510405 Department of Spinal Orthopaedics, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, Guangdong, China  
莫凌 MO Ling 广州中医药大学第一附属医院脊柱骨科, 广东 广州 510405  
任辉 REN Hui 广州中医药大学, 广东 广州 510405 Department of Spinal Orthopaedics, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, Guangdong, China  
崔健超 CUI Jian-chao 广州中医药大学第一附属医院脊柱骨科, 广东 广州 510405  
梁德 LIANG De 广州中医药大学第一附属医院脊柱骨科, 广东 广州 510405 7319890789@qq.com 
杨志东 YANG Zhi-dong 广州中医药大学第一附属医院脊柱骨科, 广东 广州 510405  
张顺聪 ZHANG Shun-cong 广州中医药大学第一附属医院脊柱骨科, 广东 广州 510405  
张志达 ZHANG Zhi-da 广州中医药大学, 广东 广州 510405 Department of Spinal Orthopaedics, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, Guangdong, China  
期刊信息:《中国骨伤》2016年29卷,第9期,第836-840页
DOI:10.3969/j.issn.1003-0034.2016.09.013
基金项目:广东省自然科学基金(编号:2014A030310082);广东省中医药科学院联合科研项目(编号:2014A020221021)


目的:探讨发生多发骨质疏松椎体压缩骨折的相关因素。

方法:回顾性分析2011年3月至2015年3月收治的199例骨质疏松性椎体压缩骨折患者病史及影像学资料,根据骨折椎体的数量分为单椎体骨折组与多椎体骨折组,采用非条件 Logistic 回归分析可能影响发生多椎体骨折的危险因素。

结果:多椎体骨折组(71例)与单椎体骨折组(128例)的年龄、性别、体重质量指数(BMI)、既往高血压、糖尿病史差异均无统计学意义,而两组骨密度T值与脊柱畸形指数差异有统计学意义,多椎体骨折组骨密度较单椎体骨折组降低,而SDI评分高于单椎体骨折组。非条件Logistic回归分析发现脊柱畸形指数与多椎体骨折明显相关,其中脊柱畸形指数[2≤脊柱畸形指数<4,OR=2.587,95% CI(1.148,5.828);脊柱畸形指数≥-4,OR=7.775,95% CI(3.272,18.478)]及骨密度T值<-4.5SD,OR=2.608,95% CI(1.038,6.551)]差异有统计学意义。

结论:骨密度越低,脊柱畸形指数评分越高,发生多椎体骨折的危险性越高。
[关键词]:骨质疏松  脊柱骨折  骨密度  危险因素
 
Risk factors for multiple-level osteoporosis vertebral compression fractures
Abstract:

Objective: To identify risk factors associated with patients suffered multiple-level osteoporosis vertebral compression fractures(OVCFs).

Methods: From March 2011 to March 2015,199 patients suffered osteoporotic were classified into multiple-level OVCFs group and single level OVCF group. Multivariate logistic regression analysis were performed to identify risks factors associated with multiple-level OVCFs.

Results: All the patients underwent OVCF,including 71 multiple-level OVCFs and 128 single level OVCF. There were no differences in the age,gender,BMI,hypertension and diabetes between two groups. While multiple-level OVCFs were associated with spinal deformity index SDI[(2≤SDI<4,OR=2.587,95% CI(1.148,5.828);SDI≥-4,OR=7.775,95% CI(3.272,18.478)],BMD[(T<-4.5SD,OR=2.608,95% CI(1.038,6.551)].

Conclusion: SDI and BMD might be the risk factors for multiple-level OVCFs.
KEYWORDS:Osteoporosis  Spinal fractures  Bone density  Risk factors
 
引用本文,请按以下格式著录参考文献:
中文格式:林顺鑫,江晓兵,沈耿杨,莫凌,任辉,崔健超,梁德,杨志东,张顺聪,张志达.多发骨质疏松椎体压缩骨折的相关因素研究[J].中国骨伤,2016,29(9):836~840
英文格式:LIN Shun-xin,JIANG Xiao-bing,SHEN Geng-yang,MO Ling,REN Hui,CUI Jian-chao,LIANG De,YANG Zhi-dong,ZHANG Shun-cong,ZHANG Zhi-da.Risk factors for multiple-level osteoporosis vertebral compression fractures[J].zhongguo gu shang / China J Orthop Trauma ,2016,29(9):836~840
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