| 软骨细胞周基质对软骨细胞作用的研究进展 |
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Received:May 20, 2014
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| 作者 | Author | 单位 | Unit | E-Mail |
| 韩俊亮 |
HAN Jun-liang |
山西医科大学第二医院骨科, 山西省骨与软组织损伤修复山西省重点实验室, 太原 030001 |
Department of Orthopaedics, the Second Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi, China |
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| 段王平 |
DUAN Wang-ping |
山西医科大学第二医院骨科, 山西省骨与软组织损伤修复山西省重点实验室, 太原 030001 |
Department of Orthopaedics, the Second Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi, China |
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| 史光华 |
SHI Guang-hua |
山西医科大学第二医院骨科, 山西省骨与软组织损伤修复山西省重点实验室, 太原 030001 |
Department of Orthopaedics, the Second Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi, China |
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| 苑伟 |
YUAN Wei |
山西医科大学第二医院骨科, 山西省骨与软组织损伤修复山西省重点实验室, 太原 030001 |
Department of Orthopaedics, the Second Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi, China |
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| 卫小春 |
WEI Xiao-chun |
山西医科大学第二医院骨科, 山西省骨与软组织损伤修复山西省重点实验室, 太原 030001 |
Department of Orthopaedics, the Second Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi, China |
weixiaochun11@126.com |
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| 期刊信息：《中国骨伤》2015年28卷，第6期，第576-579页 |
| DOI：10.3969/j.issn.1003-0034.2015.06.022 |
| 基金项目:国家自然基金(编号:31271033,31340010);2013年山西省基础研究计划项目(编号:2013021036 -3) |
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| 软骨细胞周基质(pericellular matrix,PCM)是软骨细胞周围的狭窄基质条带, 与其包绕的软骨细胞共同组成软骨单位。大量研究表明PCM富含蛋白多糖、胶原蛋白和纤维蛋白, 且在调节软骨细胞代谢微环境方面发挥着重要作用。用微管吮吸技术直接检测软骨单位发现, PCM与软骨细胞和软骨细胞外基质的力学特性明显不同。然而, 关于PCM的功能还不是十分明确, 仍需进一步研究。 |
| [关键词]:软骨细胞 细胞周基质 综述文献 |
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| Research on pericellular matrix properties for chondrcytes |
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| Abstract:Pericellular matrix(PCM) is a narrow tissue region surrounding chondrocytes, which "chondron" with its enclosed cells. A number of studies suggested that PCM is rich in proteoglycans, collagen and fibronectin, and plays an important role in regulating microenvironment of chondrocytes. Direct measures of PCM properties through micropipette aspiration technique showed that PCM was different from mechanical property of chondrocytes and nature extracellular matrix. However, the function of PCM is not clear, and need further study. |
| KEYWORDS:Chondrocytes Pericellular matrix Revies literature |
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| 引用本文，请按以下格式著录参考文献： |
| 中文格式: | 韩俊亮,段王平,史光华,苑伟,卫小春.软骨细胞周基质对软骨细胞作用的研究进展[J].中国骨伤,2015,28(6):576~579 |
| 英文格式: | HAN Jun-liang,DUAN Wang-ping,SHI Guang-hua,YUAN Wei,WEI Xiao-chun.Research on pericellular matrix properties for chondrcytes[J].zhongguo gu shang / China J Orthop Trauma ,2015,28(6):576~579 |
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