| 慢性腰痛对脊旁多裂肌萎缩影响的临床研究 |
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Received:December 05, 2013
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| 作者 | Author | 单位 | Unit | E-Mail |
| 吴巍巍 |
WU Wei-wei |
宁波市鄞州第二医院骨科, 浙江 宁波 315000
浙江大学医学院附属邵逸夫医院骨科, 浙江大学邵逸夫临床医学研究所, 浙江 杭州 310016 |
Department of Orthopaedics, Sir Run Run Shaw Hospital, Medical College of Zhejiang University, Institute of Clinical Medicine of Zhejiang University, Hangzhou 310016, Zhejiang, China |
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| 胡志军 |
HU Zhi-jun |
浙江大学医学院附属邵逸夫医院骨科, 浙江大学邵逸夫临床医学研究所, 浙江 杭州 310016 |
Department of Orthopaedics, Sir Run Run Shaw Hospital, Medical College of Zhejiang University, Institute of Clinical Medicine of Zhejiang University, Hangzhou 310016, Zhejiang, China |
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| 范顺武 |
FAN Shun-wu |
浙江大学医学院附属邵逸夫医院骨科, 浙江大学邵逸夫临床医学研究所, 浙江 杭州 310016 |
Department of Orthopaedics, Sir Run Run Shaw Hospital, Medical College of Zhejiang University, Institute of Clinical Medicine of Zhejiang University, Hangzhou 310016, Zhejiang, China |
fansw@srrsh.com |
| 徐文斌 |
XU Wen-bin |
浙江大学医学院附属邵逸夫医院骨科, 浙江大学邵逸夫临床医学研究所, 浙江 杭州 310016 |
Department of Orthopaedics, Sir Run Run Shaw Hospital, Medical College of Zhejiang University, Institute of Clinical Medicine of Zhejiang University, Hangzhou 310016, Zhejiang, China |
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| 方向前 |
FANG Xiang-qian |
浙江大学医学院附属邵逸夫医院骨科, 浙江大学邵逸夫临床医学研究所, 浙江 杭州 310016 |
Department of Orthopaedics, Sir Run Run Shaw Hospital, Medical College of Zhejiang University, Institute of Clinical Medicine of Zhejiang University, Hangzhou 310016, Zhejiang, China |
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| 赵凤东 |
ZHAO Feng-dong |
浙江大学医学院附属邵逸夫医院骨科, 浙江大学邵逸夫临床医学研究所, 浙江 杭州 310016 |
Department of Orthopaedics, Sir Run Run Shaw Hospital, Medical College of Zhejiang University, Institute of Clinical Medicine of Zhejiang University, Hangzhou 310016, Zhejiang, China |
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| 期刊信息：《中国骨伤》2014年27卷，第3期，第207-212页 |
| DOI：10.3969/j.issn.1003-0034.2014.03.009 |
| 基金项目:国家自然科学基金（编号：81301585、81171739、81101378、81271971、81271972、31270997）；浙江省自然科学基金（编号：Y2110372、LQ13H060001）；浙江省医药卫生科研项目（编号：201336877） |
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目的：明确慢性腰痛对脊旁多裂肌净横截面积大小及脂肪化程度的影响。
方法：2010年3月至2013年8月对门诊治疗的腰痛患者进行回顾性分析，最终筛选出31例符合非特异性慢性腰痛患者，其中男19例，女12例；年龄23～55岁，平均36.4岁。主要症状是反复腰痛，病程大于1年，X线、CT、MRI均未见明显异常。采用MRI成像测量同一病例先后不同时间点多裂肌净横截面积及T2信号比率的变化，再获取2次MRI检查时VAS和Oswestry功能障碍评分，分析先后2次测量多裂肌净面积及T2信号比率的变化与腰痛的病程、VAS、Oswestry功能障碍评分的相关性，从而得出腰痛对脊旁多裂肌的影响。
结果：同一病例第2次MRI检查多裂肌净横截面积明显小于第1次MRI检查，T2信号比率则明显高于第1次MRI检查（P<0.05）.多裂肌净横截面积减小率与VAS评分、病程和Oswestry功能障碍评分均呈正相关（P<0.001），而T2信号比率增加率与VAS评分、病程和Oswestry功能障碍评分均无相关性（P>0.05）.
结论：慢性腰痛是脊旁多裂肌萎缩和脂肪化的重要原因，腰痛时间、程度和功能障碍程度均与多裂肌萎缩呈正相关。 |
| [关键词]:腰痛 多裂肌 肌萎缩 脂肪浸润 |
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| Influencing of chronic low back pain on multifidus muscle atrophy |
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Abstract:
Objective: To identify the affect of chronic low back pain on multifidus muscle atrophy and fatty infiltration.
Methods: From March 2010 to August 2013,a retrospective study were carried out in the department of orthopedics of patients with low back pain. Finally 31 cases were selected to this study including 19 males and 12 females with an average age of 36.4 years ranging from 23 to 55 years. The main symptoms of these patients were repeated back pain. Duration was more than 1 year. X-ray,CT,MRI showed no obvious abnormalities. The changes of net cross-sectional area of multifidus and T2 signal ratio of the same patient were measured at different time by MRI. VAS and Oswestry disability scores were recorded in two MRI examination. Correlation between these change of multifidus net area and T2 signal ratio in two times measurement and duration of low back pain,VAS,Oswestry disability scores were analyzed to find the affection of low back pain on paraspinal multifidus muscle.
Results: The net multifidus cross-sectional area in same case by the second follow-up MRI is significantly smaller than that of the first follow-up,T2 signal ratio at second was significantly higher than that of the first(P<0.05). The net cross sectional area of multifidus muscles reduced rate were positively correlated with VAS scores,duration and of Oswestry disabilitry scores(P<0.001). The rate of increase in T2 signal ratio was not correlated with VAS scores,duration and the Oswestry disability scores(P>0.05).
Conclusion: Chronic low back pain is one of the most important reasons of paraspinal multifidus muscle atrophy and fatty. The duration,VAS and Oswestry disability scores of chronic low back pain were positively correlated with the multifidus muscle atrophy. |
| KEYWORDS:Low back pain Multifidus muscle Muscular atrophy Fatty infiltration |
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| 引用本文，请按以下格式著录参考文献： |
| 中文格式: | 吴巍巍,胡志军,范顺武,徐文斌,方向前,赵凤东.慢性腰痛对脊旁多裂肌萎缩影响的临床研究[J].中国骨伤,2014,27(3):207~212 |
| 英文格式: | WU Wei-wei,HU Zhi-jun,FAN Shun-wu,XU Wen-bin,FANG Xiang-qian,ZHAO Feng-dong.Influencing of chronic low back pain on multifidus muscle atrophy[J].zhongguo gu shang / China J Orthop Trauma ,2014,27(3):207~212 |
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