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磷酸钙骨水泥球囊撑开椎体成形术治疗骨质疏松性椎体骨折
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作者Author单位UnitE-Mail
葛付涛 GE Fu-tao 吉林大学第一医院脊柱外科, 吉林 长春 130021 Department of Spine Surgery, the First Hospital of Jilin University, Changchun 130021, Jinlin, China  
赵松 ZHAO Song 吉林大学第一医院脊柱外科, 吉林 长春 130021 Department of Spine Surgery, the First Hospital of Jilin University, Changchun 130021, Jinlin, China  
牛丰 NIU Feng 吉林大学第一医院脊柱外科, 吉林 长春 130021 Department of Spine Surgery, the First Hospital of Jilin University, Changchun 130021, Jinlin, China niufengspine@126.com 
张新 ZHANG Xin 吉林大学第一医院脊柱外科, 吉林 长春 130021 Department of Spine Surgery, the First Hospital of Jilin University, Changchun 130021, Jinlin, China  
期刊信息:《中国骨伤》2014年27卷,第2期,第128-132页
DOI:10.3969/j.issn.1003-0034.2014.02.009


目的:评估磷酸钙骨水泥(calcium phosphate cement,CPC)球囊撑开椎体成形术治疗骨质疏松性椎体骨折(osteoporotic vertebral fractures,OVF)的临床疗效.

方法:自2009年1月至2011年1月采用CPC球囊撑开椎体成形术治疗26例(31椎体)骨质疏松性椎体骨折患者,其中男15例,女11例;年龄60~89岁,平均(71.67±4.36)岁;病程0.5~7 d,平均3.2 d.采用视觉模拟评分(visual analogue scale,VAS)和功能障碍指数(oswestry disability index,ODI)对疼痛和功能进行评定. 通过X线对椎体高度的丢失和后凸畸形角度进行观察.

结果:所有患者获得随访,时间10~24个月,平均18个月. 术前、术后24 h、末次随访时VAS评分分别为7.91±1.20、3.22±1.12、1.92±0.83,ODI评分分别为40.00±1.15、17.00±2.12、13.00±1.42,椎体高度分别为(18.21±3.21)、(23.82±3.10)、(21.85±3.24) mm,后凸畸形角度分别为(18.21±3.21)°、(7.42±3.13)°、(10.01°±3.11)°,术后24 h、末次随访与术前比较差异有统计学意义(P<0.05),术后24 h与末次随访比较差异无统计学意义(P>0.05).

结论:CPC球囊撑开椎体成形术是治疗骨质疏松性椎体骨折的有效方法,能迅速缓解疼痛,有效的恢复椎体骨折椎体高度及纠正后凸畸形角度,具有创伤小、安全性好的优点.
[关键词]:椎体成形术  磷酸钙骨水泥  骨质疏松  骨折
 
Treatment of osteoporotic vertebral fractures with percutaneous balloon kyphoplasty using calcium phosphate cement
Abstract:

Objective: To assess the clinical outcomes of balloon kyphoplasty assisted with calcium phosphate cement (CPC) in treating osteoporotic vertebral fractures(OVF).

Methods: From January 2009 to January 2011,26 patients with osteoporotic vertebral fractures were treated with balloon kyphoplasty assisted with CPC,including 31 vertebrae. There were 15 males and 11 females with an average age of (71.67±4.36) years old (ranged from 60 to 89 years). Course of disease was from 0.5 to 7 days with an average of 3.2 days. Clinical outcomes were assessed by the visual analogue scale (VAS) and the oswestry disability index (ODI). Vertebral height loss and kyphotic angle were measured by X-rays.

Results: All patients were followed up for 10 to 24 months with an average of 18 months. Before operation,24 hours after operation and at final follow-up,VAS scores were 7.91±1.20,3.22±1.12,1.92±0.83,respectively;ODI scores were 40.00±1.15,17.00±2.12,13.00±1.42,respectivesly;vertebral heights were (18.21±3.21),(23.82±3.10),(21.85±3.24) mm,respectivesly;vertebral kyphosis angles were (18.21±3.21)°,(7.42±3.13) °,(10.01±3.11) °,respectivesly. There was significant difference between preoperation and 24 hours after operation,and between final follow-up and preoperation(P<0.05). There was no significant difference between final follow-up and 24 hours after operation(P>0.05).

Conclusion: Balloon kyphoplasty assisted with calcium phosphate cement(CPC) is effective for the treatment of osteoporotic vertebral fractures(OVF),which can expeditiously relieve pain and effectively rebuild height of vertebral body and kyphotic angle,and also has advantages of minimal trauma and good security.
KEYWORDS:Vertebroplasty  Calcium phosphate cement  Osteoporosis  Fractures
 
引用本文,请按以下格式著录参考文献:
中文格式:葛付涛,赵松,牛丰,张新.磷酸钙骨水泥球囊撑开椎体成形术治疗骨质疏松性椎体骨折[J].中国骨伤,2014,27(2):128~132
英文格式:GE Fu-tao,ZHAO Song,NIU Feng,ZHANG Xin.Treatment of osteoporotic vertebral fractures with percutaneous balloon kyphoplasty using calcium phosphate cement[J].zhongguo gu shang / China J Orthop Trauma ,2014,27(2):128~132
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