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基因治疗非创伤性股骨头坏死的研究进展

Hits: 2356 Download times: 325 Received:November 22, 2011

作者	Author	单位	Unit	E-Mail
周明旺	ZHOU Ming-wang	甘肃省中医院,甘肃兰州 730050 天津中医药大学	Gansu Hospital of Traditional Chinese Medicine,Lanzhou 730050,Gansu,China	zmw2006@126.com
李盛华	LI Sheng-hua	甘肃省中医院,甘肃兰州 730050
郭铁峰	GUO Tie-feng	甘肃中医学院

期刊信息：《中国骨伤》2012年25卷，第6期，第525-529页

DOI：10.3969/j.issn.1003-0034.2012.06.023

基金项目:国家自然科学基金(面向项目)(编号:81072821)
Fund programs:Supported by a Grant from National Natural Science Foundation of China (Greneral Program)(No.81072821)

非创伤性股骨头坏死早期保守治疗方法甚多,但尚缺乏一种成熟有效的治疗方法.基因治疗非创伤性股骨头坏死是近年来新型的治疗方法,本文就该病的发病机制、分子生物学基础、外源性治疗基因与载体选择等方面研究的相关进展及存在问题展开综述,讨论了研究的有关问题及对策,并就研究前景进行了展望.

[关键词]:股骨头坏死治疗基因综述文献

Research progress of gene therapy in the treatment of non-traumatic osteonecrosis of femoral head

Abstract:ABSTRACT There are many methods of conservative treatment for early non-traumatic osteonecrosis of femoral head,but still lack of a mature and effective treatment. Gene therapy is a new treatment method for non-traumatic osteonecrosis of femoral head in recent years. This article showed that the non-traumatic osteonecrosis of femoral head related to progress and problems on pathogenesy,molecular biology foundation,exogenous theoretical gene,carrier selection and so on,discussed some problems and countermeasure and future applications.

KEYWORDS:Femur head necrosis Therapy Genes Review literature

引用本文，请按以下格式著录参考文献：

中文格式:	周明旺,李盛华,郭铁峰.基因治疗非创伤性股骨头坏死的研究进展[J].中国骨伤,2012,25(6):525~529
英文格式:	ZHOU Ming-wang,LI Sheng-hua,GUO Tie-feng.Research progress of gene therapy in the treatment of non-traumatic osteonecrosis of femoral head[J].zhongguo gu shang / China J Orthop Trauma ,2012,25(6):525~529

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