| 膝骨关节炎应用脉冲电磁场治疗的系统评价 |
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Received:March 08, 2012
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| 期刊信息：《中国骨伤》2012年25卷，第5期，第384-388页 |
| DOI：10.3969/j.issn.1003-0034.2012.05.008 |
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目的：系统评价脉冲电磁场治疗膝骨关节炎的临床效果。
方法：应用Cochrane系统评价方法计算机检索Cochrane Library(2012年第2期)、PubMed(1966～2012.2)、EMBASE(1974～2012.2)、中国生物医学数据库(CBM,1978～2012.2)、中国期刊全文数据库(CNKI,1979～2012.2)和维普数据库(VIP,1989～2012.2),同时在Google学术搜索引擎进行检索,并追查纳入研究参考文献,收集以脉冲电磁场治疗膝骨关节炎的所有随机对照试验。根据Cochrane协作网推荐的“风险评估工具”进行偏倚风险评估,用RevMan 5.1 软件进行统计学分析。
结果：最终纳入5个随机对照试验,共331例患者。研究结果显示：与安慰剂相比,脉冲电磁场治疗膝骨关节炎在缓解疼痛[WMD=0.12,95%CI(-0.46,0.69)]、减少晨僵时间[WMD=0.08,95%CI(-0.05,0.21)]和改善膝关节功能[WMD=-1.16,95%CI(-4.36,2.05)]等方面差异无统计学意义。
结论：脉冲电磁场治疗膝骨关节炎的疗效需更多有力的证据。由于纳入研究质量和病例数量的局限,上述结论尚需更多高质量的随机对照试验进一步验证。 |
| [关键词]:骨关节炎,膝 电磁场 Meta分析 随机对照试验 |
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| Pulsed electromagnetic field therapy for the treatment of knee osteoarthritis:a systematic review |
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Abstract:
Objective:To evaluate the clinical effectiveness of pulsed electromagnetic field therapy in the treatment of knee osteoarthritis.
Methods:Based on the principles and methods of Cochrane systematic reviews,the authors searched the Cochrane Library(2012,2 issue),PubMed(1966 to February,2012),EMBASE(1974 to February,2012),Chinese Bio-medicine Database(1978 to February,2012),China Journal Full-text Database(1979 to February,2012),VIP database (1989 to February,2012),as well as search engine Google Scholar. Randomized controlled trials (RCTs) of pulsed electromagnetic field therapy to treat knee osteoarthritis were included. The authors assessed the quality of the included trials according to the Cochrane Handbook for Systematic Reviews of Interventions Version. The Cochrane Collaboration's software RevMan 5.1 was used for meta-analysis.
Results:Five RCTs totaling 331 patients were included. The results showed that compared with placebo control treatment,pulsed electromagnetic field therapy had little clinical benefit in relieving the pain of knee osteoarthritis [WMD=0.12,95%CI(-0.46,0.69)],reducing morning stiffness time[WMD=0.08,95%CI(-0.05,0.21)] and improving the knee function [WMD=-1.16,95%CI(-4.36,2.05)]. There were no significant differences between the two groups.
Conclusion:The effects of Pulsed electromagnetic field therapy for treating knee osteoarthritis need more powerful trails to be confirmed. The above conclusions still need more high-quality randomized controlled trails to be verified owing to the limitations of the number and the quality of systematic review included studies. |
| KEYWORDS:Osteoarthritis,knee Electromagnetic fields Meta-analysis Randomized controlled trials |
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| 引用本文，请按以下格式著录参考文献： |
| 中文格式: | 曹立颖,姜明静,杨声坪,赵龙,王建民.膝骨关节炎应用脉冲电磁场治疗的系统评价[J].中国骨伤,2012,25(5):384~388 |
| 英文格式: | CAO Li-ying,JIANG Ming-jing,YANG Sheng-ping,ZHAO Long,WANG Jian-min.Pulsed electromagnetic field therapy for the treatment of knee osteoarthritis:a systematic review[J].zhongguo gu shang / China J Orthop Trauma ,2012,25(5):384~388 |
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