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Genex椎体成形在胸腰椎爆裂性骨折治疗中的意义
Hits: 2761   Download times: 1322   Received:July 06, 2010    
作者Author单位UnitE-Mail
占蓓蕾 ZHAN Bei-lei 衢州中心医院,浙江 衢州 324000 Centre Hospital of Quzhou,Quzhou 324000,Zhejiang,China zbl67899@126.com 
叶舟 YE Zhou 衢州中心医院,浙江 衢州 324000 Centre Hospital of Quzhou,Quzhou 324000,Zhejiang,China  
期刊信息:《中国骨伤》2011年24卷,第3期,第223-226页
DOI:10.3969/j.issn.1003-0034.2011.03.014


目的:探讨Genex椎体成形与椎弓根钉系统复位固定胸腰椎爆裂性骨折的方法与疗效。

方法:自2007年2月至2009年10月,应用Genex人工骨椎体成形与椎弓根钉系统复位固定胸腰椎爆裂性骨折38例,其中男25例,女13例;平均年龄42岁(30~68岁).致伤原因:车祸伤9例,压砸伤7例,坠落伤21例,其他伤1例。骨折类型按Denis分类:A型6例,B型22例,C型7例,D型3例。神经功能损害按(ASIA)标准分级:A级4例,B级7例,C级10例,D级6例,E级11例。术后通过X线片、CT检查以及(ASIA)神经功能评定标准评价手术疗效。

结果:38例均获随访,时间6~34个月,平均16.5个月。术后1周X线检查:脊柱序列恢复正常,术后椎体前缘高度恢复(98.50±2.17)%,椎体后缘高度恢复(98.87±1.82)%,Cobb角降(1.63±2.15)°,椎管狭窄率恢复(1.45±3.47)%.术后6个月X线片显示椎体高度、Cobb角恢复无丢失,椎体骨组织密度接近正常。CT扫描发现椎体内骨缺损完全消失,骨缺损区已为正常骨组织。术后神经功能均有1~2级的恢复。

结论:Genex人工骨作为植骨材料进行椎体成形术,生物相容性好,骨诱导能力强,椎体高度及Cobb角丢失少,近期效果满意。
[关键词]:胸椎  腰椎  骨折  骨折固定术  骨移植
 
Significance of percutaneous vertebroplasty with Genex in the treatment of thoracolumbar burst fractures
Abstract:

Objective: To explore the therapeutic effects of percutaneous vertebroplasty with Genex combined with pedical screw fixation in the treatment of thoracolumbar burst fractures.

Methods: From February 2007 to October 2009,38 patients with thoracolumbar burst fractures were treated with percutaneous vertebroplasty with Genex and pedical screw fixation. There were 25 males and 13 females,with a mean age of 42 years old(ranged,30 to 68 years). The cause of injuries included road accident of 9 cases,crush injury of 7 cases,crash of 21 cases and others of 1 case. The fractures were classified according to Denis classification:6 cases of type A,22 cases of type B,7 cases of type C and 3 cases of type D. Functional assessment of nerves was assesed according to ASIA criteria:4 cases of type A,7 cases of type B,10 cases of type C,6 cases of type D and 11 cases of type E. Therapeutic effects were assessed by imaging and ASIA standard.

Results: All the patients were followed up,and the duration ranged from 6 months to 34 months,with a mean period of 16.5 months. The results were observed after 1 week by X-ray inspection that vertebrate column array of all patients were restored to normal,anterior height of centrum restored to (98.50±2.17)%,posterior height of centrum for (98.87±1.82)%;and Cobb angle of injured vertebra decreased to average of(1.63±2.15) degree;the stenosis rate restored to(1.45±3.47)%. By X-ray inspection,it was observed that the vertebral height kept good at 6 months after operation,and the bone density almostly normal. By CT scanning,it was observed that bone defects of vertebrae disappeared,and restored to normal bony tissue. The nerve function restored 1 to 2 grades 6 months after operation.

Conclusion: Artificial bone of Genex applied in vertebral body-plasty has good biocompatibility,strong bone inducibility,no complications,little loss of vertebrae height and Cobb angle,and satisfactory results in the near future.
KEYWORDS:Thoracic vertebrae  Lumbar vertebrae  Fractures  Fracture fixation  Bone transplantation
 
引用本文,请按以下格式著录参考文献:
中文格式:占蓓蕾,叶舟.Genex椎体成形在胸腰椎爆裂性骨折治疗中的意义[J].中国骨伤,2011,24(3):223~226
英文格式:ZHAN Bei-lei,YE Zhou.Significance of percutaneous vertebroplasty with Genex in the treatment of thoracolumbar burst fractures[J].zhongguo gu shang / China J Orthop Trauma ,2011,24(3):223~226
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