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骨折动物模型的研究进展

Hits: 2868 Download times: 1244 Received:April 13, 2010

作者	Author	单位	Unit	E-Mail
汤译博	TANG Yi-bo	第二军医大学附属长海医院骨科，上海 200433	Department of Orthopaedics,the Affiliated Changhai Hospital of the 2nd Military University,Shanghai 200433,China
赵亮	ZHAO Liang	第二军医大学附属长海医院骨科，上海 200433	Department of Orthopaedics,the Affiliated Changhai Hospital of the 2nd Military University,Shanghai 200433,China
苏佳灿	SU Jia-cai	第二军医大学附属长海医院骨科，上海 200433	Department of Orthopaedics,the Affiliated Changhai Hospital of the 2nd Military University,Shanghai 200433,China	sujiacan@yahoo.com.cn

期刊信息：《中国骨伤》2011年24卷，第1期，第91-93页

DOI：10.3969/j.issn.1003-0034.2011.01.028

基金项目:上海市科委纳米专项基金(编号：0852nm04300);上海市人事局人才发展资金(编号：2009003);上海市卫生局专项基金(编号：2009S018)

随着传统重工业和交通事业的飞速发展，骨折的发生率逐年升高。临床上骨折的发生原因、机制、愈合及其影响因素极多，尤其是骨折愈合是一个长期而复杂的过程，并且受到稳定性、血供、感染、外部刺激等多因素的影响，若措施不当会对患者造成伤害。制备正确的动物模型可以准确模拟骨折发生，有效地指导临床实践。本文就骨折动物模型的材料、制备、应用等做一简要综述，以期能为正确合理地选择骨折动物模型提供一定的参考。

[关键词]:骨折模型，动物骨折愈合综述文献

Research progress of animal model of fracture

Abstract:Accompanying with the development of traditional heavy industry and traffic condition,the incidence of fracture appears an upward trend significantly. There are different reasons,mechanisms,healing styles of fracture. Furthermore,the healing of fracture is a long and complex procedure,affected by many contributing factors,such as stability,blood supply,infection. A suitable animal model can copy the clinical situation closely,representing an essential tool to analyze the biology of fracture healing. This article makes a brief review on the material,technique,selection,and development of animal models in fracture-healing research,looking forward to providing some reference on choosing an animal model correctly and reasonably.

KEYWORDS:Fractures Model,animal Fracture healing Review literature

引用本文，请按以下格式著录参考文献：

中文格式:	汤译博,赵亮,苏佳灿.骨折动物模型的研究进展[J].中国骨伤,2011,24(1):91~93
英文格式:	TANG Yi-bo,ZHAO Liang,SU Jia-cai.Research progress of animal model of fracture[J].zhongguo gu shang / China J Orthop Trauma ,2011,24(1):91~93

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