| Wnt信号通路与骨关节炎 |
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Received:December 14, 2009
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| 作者 | Author | 单位 | Unit | E-Mail |
| 高宁阳 |
GAO Ning-yang |
上海市中医药研究院骨伤科研究所,上海 201203 |
Institution of Orthopaedics,Academy of TCM of Shanghai,Shanghai 201203,China |
sapphire512@163.com |
| 曹月龙 |
CAO Yue-long |
上海市中医药研究院骨伤科研究所,上海 201203 |
Institution of Orthopaedics,Academy of TCM of Shanghai,Shanghai 201203,China |
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| 刘婷 |
LIU Ting |
上海市中医药研究院骨伤科研究所,上海 201203 |
Institution of Orthopaedics,Academy of TCM of Shanghai,Shanghai 201203,China |
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| 庞坚 |
PANG Jian |
上海市中医药研究院骨伤科研究所,上海 201203 |
Institution of Orthopaedics,Academy of TCM of Shanghai,Shanghai 201203,China |
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| 詹红生 |
ZHAN Hong-sheng |
上海市中医药研究院骨伤科研究所,上海 201203 |
Institution of Orthopaedics,Academy of TCM of Shanghai,Shanghai 201203,China |
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| 石印玉 |
SHI Yin-yu |
上海市中医药研究院骨伤科研究所,上海 201203 |
Institution of Orthopaedics,Academy of TCM of Shanghai,Shanghai 201203,China |
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| 期刊信息：《中国骨伤》2010年23卷，第4期，第320-323页 |
| DOI：10.3969/j.issn.1003-0034.2010.04.030 |
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| Wnt信号通路广泛地存在于各种属生物体中，调节控制着许多生命过程，如细胞形态与功能的分化及维持、免疫、应激、凋亡等。随着对其研究的不断深入，发现Wnt信号通路对早期软骨的化生与形成、体外软骨细胞的增殖与分化具有重要的作用，并已成为骨关节炎(osteoarthritis,OA)发病机制研究的新热点。 |
| [关键词]:软骨细胞 骨关节炎 Wnt信号通路 β-连环蛋白 综述文献 |
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| Wnt signaling pathways and osteoarthritis |
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| Abstract:The Wnt signaling exists in every kinds of species and regulates a variety of biological processes including cell fate,proliferation and function,immunity,stress,apoptosis and so on. During the researching,Wnt signaling also plays an important role in chondrocyte differentiation and maturation. So it has been the new spot in pathogenesis of osteoarthritis study. |
| KEYWORDS:Chondrocytes Osteoarthritis Wnt signaling pathways β-catenin Review literature |
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| 引用本文，请按以下格式著录参考文献： |
| 中文格式: | 高宁阳,曹月龙,刘婷,庞坚,詹红生,石印玉.Wnt信号通路与骨关节炎[J].中国骨伤,2010,23(4):320~323 |
| 英文格式: | GAO Ning-yang,CAO Yue-long,LIU Ting,PANG Jian,ZHAN Hong-sheng,SHI Yin-yu.Wnt signaling pathways and osteoarthritis[J].zhongguo gu shang / China J Orthop Trauma ,2010,23(4):320~323 |
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