盘内注射胶原酶治疗上段腰椎间盘突出症 |
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作者 | Author | 单位 | Unit | E-Mail |
燕春山 |
YAN Chun-shan |
解放军第404医院风湿科,山东威海264200 |
Rheumatism Department of the 404th Hospital of PLA,Weihai 264200,Shandong,China |
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从凤英 |
CONG Feng-ying |
济南军区总院 |
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刘玉波 |
LIU Yu-bo |
解放军第404医院风湿科,山东威海264200 |
Rheumatism Department of the 404th Hospital of PLA,Weihai 264200,Shandong,China |
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刘晓光 |
LIU Xiao-guang |
解放军第404医院风湿科,山东威海264200 |
Rheumatism Department of the 404th Hospital of PLA,Weihai 264200,Shandong,China |
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郑晓红 |
ZHENG Xiao-hong |
解放军第404医院风湿科,山东威海264200 |
Rheumatism Department of the 404th Hospital of PLA,Weihai 264200,Shandong,China |
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期刊信息:《中国骨伤》2007年20卷,第11期,第767-768页 |
DOI:doi:10.3969/j.issn.1003-0034.yyyy.nn.zzz |
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目的:探讨盘内注射胶原酶的方法治疗上段腰椎间盘突出症的可行性、疗效及安全性。
方法:28例单纯上段腰椎间盘突出症患者,男16例,女12例;年龄21~62岁,平均44.5岁。病程3个月~10年。椎间盘突出4~9mm,平均4.9mm。采用椎旁进针盘内注射或突出物内注射胶原酶的方法进行治疗,随访观察有效率、突出椎间盘溶解、椎间隙感染等并发症发生情况。
结果:所有患者随访1~6个月,依据Macnab评价标准进行疗效评价,优9例,良12例,可4例,无效3例。突出椎间盘溶解0~6mm,平均3.5mm。17例进行了重复注射,其中9例患者进行了3次注射。13例注射后短期内症状加重,对症处理后缓解。
结论:盘内注射胶原酶的方法治疗上段腰椎间盘突出症效果理想、安全可行。 |
[关键词]:胶原酶类 椎间盘化学松解术 椎间盘移位 腰椎 |
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Collagenase injected in disk to treat lumbar intervertebral disk herniation |
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Abstract:
Objective:To probe the therapeutic effect in the treatment of up intervertebral disc herniation by injected collagenase in disk.
Methods:There were 28 patients involving 16 males and 12 females with an average age of 44.5 years ranging from 21 to 62.The course was 3 months to 10 years.The average disc herniation was 4.9 mm ranging from 4 to 9 mm.The lumbar disc herniation were treated by collagenase injected in disk.The outcome,solution of herniated disc,complications such as infection in disc were followed and observed.
Results:All patients were followed-up for 1 to 6 months.According to evaluated standard of Macnab,the result was excellent in 9 cases,good in 12,improved in 4,and ineffective in 3.The solution of herniated disk was 0-6 mm,the average was 3.5 mm.Seventeen patients were injected twice,of which 9 patients were injected three times.There were 13 cases with symptom progression after injection herniation is short period,but the situation was relieved after therapy in time.
Conclusion:The effect of injection of collagenase in disk to treat lumber intervertebral disk herniation is an effective and safe method. |
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引用本文,请按以下格式著录参考文献: |
中文格式: | 燕春山,从凤英,刘玉波,刘晓光,郑晓红.盘内注射胶原酶治疗上段腰椎间盘突出症[J].中国骨伤,2007,20(11):767~768 |
英文格式: | YAN Chun-shan,CONG Feng-ying,LIU Yu-bo,LIU Xiao-guang,ZHENG Xiao-hong.Collagenase injected in disk to treat lumbar intervertebral disk herniation[J].zhongguo gu shang / China J Orthop Trauma ,2007,20(11):767~768 |
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