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脱钙骨基质治疗长骨骨折延迟愈合及骨不连
Hits: 2036   Download times: 1212   Received:August 20, 2006    
作者Author单位UnitE-Mail
曾逸文 ZENG Yi-wen 南京医科大学附属南京第一医院骨科,江苏南京210006 Department of Orthopaedics,Affiliated Nanjing First Hospital,Nanjing Medical University,Nanjing,210006,Jiangsu,China wangdarling@163.com 
王大林 WANG Da-lin 南京医科大学附属南京第一医院骨科,江苏南京210006 Department of Orthopaedics,Affiliated Nanjing First Hospital,Nanjing Medical University,Nanjing,210006,Jiangsu,China  
王黎明 WANG Li-ming 南京医科大学附属南京第一医院骨科,江苏南京210006 Department of Orthopaedics,Affiliated Nanjing First Hospital,Nanjing Medical University,Nanjing,210006,Jiangsu,China  
桂鉴超 GUI Jian-chao 南京医科大学附属南京第一医院骨科,江苏南京210006 Department of Orthopaedics,Affiliated Nanjing First Hospital,Nanjing Medical University,Nanjing,210006,Jiangsu,China  
徐杰 XU Jie 南京医科大学附属南京第一医院骨科,江苏南京210006 Department of Orthopaedics,Affiliated Nanjing First Hospital,Nanjing Medical University,Nanjing,210006,Jiangsu,China  
王钢锐 WANG Gang-rui 南京医科大学附属南京第一医院骨科,江苏南京210006 Department of Orthopaedics,Affiliated Nanjing First Hospital,Nanjing Medical University,Nanjing,210006,Jiangsu,China  
郑圣鼐 ZHENG Sheng-nai 南京医科大学附属南京第一医院骨科,江苏南京210006 Department of Orthopaedics,Affiliated Nanjing First Hospital,Nanjing Medical University,Nanjing,210006,Jiangsu,China  
期刊信息:《中国骨伤》2006年19卷,第11期,第654-655页
DOI:doi:10.3969/j.issn.1003-0034.yyyy.nn.zzz


目的:探讨脱钙骨基质(decalcifiedbonematrix,DBM)治疗长骨骨折延迟愈合和骨不连的疗效。

方法:长骨延迟愈合、骨不连共57例,男45例,女12例;年龄21~65岁,平均42岁。开放性骨折17例,闭合骨折40例。骨折延迟愈合32例中,肱骨4例,股骨10例,胫骨18例;骨不连25例中,肱骨5例,股骨4例,胫骨16例。全部采用DBM于骨断端处和骨缺损区植入治疗。

结果:57例患者均获随访,随访时间4~37个月,平均7.8个月。骨折延迟愈合32例中骨折愈合31例,1例胫骨骨折未愈合;骨不连25例中骨折愈合23例,2例未愈合,其中胫骨1例、肱骨1例。愈合时间3~6.6个月,平均4.7个月。

结论:DBM治疗长骨骨折延迟愈合及骨不连,其疗效满意、并发症少。
[关键词]:骨折,不愈合  脱钙骨基质  骨移植
 
Treatment of delayed union and nonunion of long bone fractures by using DBM(decalcified bone matrix)
Abstract:

Objective:To discuss the clinical effects of OSTEOSET decalcified bone matrix(DBM) in treatment of delayed union and nonunion of long bone fractures.

Methods:Fifty-seven cases of delayed union and nonunion of long bone fractures were treated with Osteoset DBM.There were 45 male and 12 female with average age of 42 years(21 to 65 years).Among them,there were 17 cases of open fracture and 40 of closed fracture.Thirty-two cases of delayed union included 4 cases of humeral fracture,10 of femoral fracture and 10 of tibial fracture;twenty-five cases of nonunion included 5 of humeral fracture,4 of femoral fracture and 16 of tibial fracture.All patients were treated by DBM transplantation on the fracture ends and bone defect zone.

Results:All 57 cases were followed-up from 4 to 37 months(7.8 months on average).In 32 cases of delayed union,31 cases got bone union,but 1 case of tibial fracture did nonunion;In 25 cases of nonunion,23 got bone union,but 2 cases did nonunion(1 tibial nonunion and 1 humeral nonunion).The union time was from 3 to 6.6 months(average 4.7 months).

Conclusion:The treatment of delayed union and nonunion of long bone fractures by using Osteoset DBM has satisfactory effect and lower complications.
KEYWORDS:Fractures,ununited  Decalcified bone matrix  Bone transplantation
 
引用本文,请按以下格式著录参考文献:
中文格式:曾逸文,王大林,王黎明,桂鉴超,徐杰,王钢锐,郑圣鼐.脱钙骨基质治疗长骨骨折延迟愈合及骨不连[J].中国骨伤,2006,19(11):654~655
英文格式:ZENG Yi-wen,WANG Da-lin,WANG Li-ming,GUI Jian-chao,XU Jie,WANG Gang-rui,ZHENG Sheng-nai.Treatment of delayed union and nonunion of long bone fractures by using DBM(decalcified bone matrix)[J].zhongguo gu shang / China J Orthop Trauma ,2006,19(11):654~655
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