| 交感神经及其递质在椎动脉型颈椎病中的调控机制 |
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Received:November 10, 2004
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| 作者 | Author | 单位 | Unit | E-Mail |
| 张军 |
ZHANG Jun |
中国中医研究院骨伤科研究所,,北京100700 |
Institute of Orthopedics and Traumatology,China Academy of TCM,Beijing,100700,China |
zhangJunMD@163.com |
| 孙树椿 |
SUN Shu-chun |
中国中医研究院骨伤科研究所,,北京100700 |
Institute of Orthopedics and Traumatology,China Academy of TCM,Beijing,100700,China |
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| 于栋 |
YU Dong |
中国中医研究院骨伤科研究所,,北京100700 |
Institute of Orthopedics and Traumatology,China Academy of TCM,Beijing,100700,China |
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| 张淳 |
ZHANG Chun |
中国中医研究院骨伤科研究所,,北京100700 |
Institute of Orthopedics and Traumatology,China Academy of TCM,Beijing,100700,China |
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| 武震 |
ZHANG Jun |
中国中医研究院骨伤科研究所,,北京100700 |
Institute of Orthopedics and Traumatology,China Academy of TCM,Beijing,100700,China |
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| 期刊信息：《中国骨伤》2005年18卷，第7期，第413-415页 |
| DOI：doi:10.3969/j.issn.1003-0034.yyyy.nn.zzz |
| 基金项目:国家科技部重点课题(编号:96-901-01-87) |
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目的:验证交感神经因素在椎动脉型颈椎病发病中对椎动脉供血不足的调控机制。
方法:将40只家兔随机分为两组:模型组和对照组,每组各20只,在造模当日及造模后4周,分别检测每组的SPNs放电次数及NA的含量。
结果:模型组胸髓侧角的SPNs放电次数57.45±7.89,56.60±7.44;对照组胸髓侧角的SPNs放电次数10.08±2.26,10.00±2.24。两组比较,P<0.001。模型组血浆中NA含量(5.48±0.46)pmol/ml,(5.36±0.43)pmol/ml;对照组血浆中NA含量(3.31±0.43)pmol/ml,(3.30±0.32)pmol/ml。两组比较,P<0.001。
结论:交感神经因素在椎动脉型颈椎病发病中对椎动脉的供血不足起到重要的调控作用。 |
| [关键词]:交感神经因素 椎动脉型颈椎病 椎动脉供血不足 动物,实验 |
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| Adjustment mechanism of sympathetic nerve and neurotransmitiers in vertebral artery type of cervical spondylosis |
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Abstract:
Objective:To evaluate the adjustment mechanism of sympathetic factor to the the blood supply for the vertebral artery.
Methods:40 domestic rabbits were equally divided into model and control group randomly.Each group was detected SPNs discharge frequency and the content of NA at the day of making model and 4 weeks later respectively.
Results:The SPNs discharge frequency in lateral horn of thoraco-spinal cord of the model group was 57.45±7.89,56.60±7.44;and the control group was 10.08±2.26,10.00±2.24.There was significant difference between model group and control group(P<0.001).The content of NA in blood plasma of the model group was (5.48±0.46) pmol/ml,(5.36±0.43) pmol/ml;and the control group was (3.31±0.43) pmol/ml,(3.30±0.32) pmol/ml.There was significant difference in the two groups (P<0.001).
Conclusion:Sympathetic factor of vertebral artery type of cervical spondylosis has important adjusting role for the blood supply deficiency of vertebral artery. |
| KEYWORDS:Sympathetic factor Cervical spondylosis of vertebral artery type Vertebrobasilar insufficiency Animals,aboratory |
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| 引用本文，请按以下格式著录参考文献： |
| 中文格式: | 张军,孙树椿,于栋,张淳,武震.交感神经及其递质在椎动脉型颈椎病中的调控机制[J].中国骨伤,2005,18(7):413~415 |
| 英文格式: | ZHANG Jun,SUN Shu-chun,YU Dong,ZHANG Chun,ZHANG Jun.Adjustment mechanism of sympathetic nerve and neurotransmitiers in vertebral artery type of cervical spondylosis[J].zhongguo gu shang / China J Orthop Trauma ,2005,18(7):413~415 |
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