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靶位注射胶原酶治疗腰椎间盘突出术后复发
Hits: 2209   Download times: 1337   Received:June 19, 2003    
作者Author单位UnitE-Mail
陈家骅 CHEN Jia-hua 安徽医科大学第一附属医院,安徽合肥230022 The 1st Affiliated Hospital of Anhui Medical University chenjiahua001@sina.com 
汤健 TANG Jian 安徽医科大学第一附属医院,安徽合肥230022 The 1st Affiliated Hospital of Anhui Medical University  
查日俊 CHA Ri-jun 安徽医科大学第一附属医院,安徽合肥230022 The 1st Affiliated Hospital of Anhui Medical University  
李元海 LI Yuan-hai 安徽医科大学第一附属医院,安徽合肥230022 The 1st Affiliated Hospital of Anhui Medical University  
刘斌 LIU Bin 安徽医科大学第一附属医院,安徽合肥230022 The 1st Affiliated Hospital of Anhui Medical University  
汪先贵 WANG Xian-gui 安徽医科大学第一附属医院,安徽合肥230022 The 1st Affiliated Hospital of Anhui Medical University  
张健 ZHANG Jian 安徽医科大学第一附属医院,安徽合肥230022 The 1st Affiliated Hospital of Anhui Medical University  
期刊信息:《中国骨伤》2004年17卷,第1期,第25-27页
DOI:doi:10.3969/j.issn.1003-0034.yyyy.nn.zzz
基金项目:安徽省卫生厅科研基金资助项目(2002A021)


目的:探讨靶位注射胶原酶治疗腰椎间盘突出术后复发的临床意义。

方法:27例术后复发患者接受注射胶原酶治疗,早期行侧隐窝注射法5例,后期行CT介入靶位注射法16例,CT介入联合靶位注射法6例。

结果:所有患者经6个月~2年随访,优9例,良8例,可5例,差5例,优良率630%,有效率815%;靶位穿刺37次,首次穿刺失败4次(1/9);4例于注射胶原酶后6~13个月复查CT,发现突出物缩小80%~90%。

结论:靶位注射胶原酶溶盘术可与手术互补,适用于腰椎间盘突出术后复发的治疗。
[关键词]:椎间盘移位  术后并发症  胶原酶  注射,硬膜外
 
Target-injection of collagenase for the treatment of recurrent postoperative lumbar disc herniation
Abstract:

Objective:To investigate the clinical significance of the target-injection of collagenase for the treatment of recurrent postoperative lumbar disc herniation.

Methods:27 patients with recurrent lumbar disc herniation at L4,5 to L5S1 were included in this study.The lateral recess injection was applied in 5 cases at early stage,the target-injection method by CT intervention in 16 cases and the combined target-injection method with CT intervention in 6 cases at later period.

Results:All patients were followed up 6 months to 2 years after treatment.9 cases got excellent result,8 cases good,5 cases fair and 5 poor.The excellent and good rate was 63.0% and the effective rate was 81.5%.There were 4 times with the miss of puncture (1/9) on the first time.The CT image showed in 6 to 13 months:The prominence was minified 80% to 90% in 4 cases.

Conclusion:The target-injection of collagenase for intervertebral disk chemolysis may be complementary therapy for recurrent postoperative lumbar disc herniation.
KEYWORDS:Intervertebral disk displacement  Postoperative complications  Collagenase  Injections,epidural
 
引用本文,请按以下格式著录参考文献:
中文格式:陈家骅,汤健,查日俊,李元海,刘斌,汪先贵,张健.靶位注射胶原酶治疗腰椎间盘突出术后复发[J].中国骨伤,2004,17(1):25~27
英文格式:CHEN Jia-hua,TANG Jian,CHA Ri-jun,LI Yuan-hai,LIU Bin,WANG Xian-gui,ZHANG Jian.Target-injection of collagenase for the treatment of recurrent postoperative lumbar disc herniation[J].zhongguo gu shang / China J Orthop Trauma ,2004,17(1):25~27
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