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刺激颈交感神经对家兔心脏功能活动变化的影响

Hits: 3619 Download times: 2382 Received:September 23, 2002

作者	Author	单位	Unit	E-Mail
齐越峰	QI Yuefeng	中国中医研究院骨伤科研究所,北京100700	Institute of Orthopaedics and Traumatology,China Academy of Traditional Chinese Medicine, Beijing 100700
张军	ZHANG Jun	中国中医研究院骨伤科研究所,北京100700	Institute of Orthopaedics and Traumatology,China Academy of Traditional Chinese Medicine, Beijing 100700
孙树椿	SUN Shuchun	中国中医研究院骨伤科研究所,北京100700	Institute of Orthopaedics and Traumatology,China Academy of Traditional Chinese Medicine, Beijing 100700
邵忠		抚顺第三医院
庞伟		辽阳市中心医院

期刊信息：《中国骨伤》2003年16卷，第5期，第278-280页

DOI：doi:10.3969/j.issn.1003-0034.yyyy.nn.zzz

目的:探讨颈椎性类冠心病时颈交感神经受累对心脏功能的影响。

方法:健康家兔30只,显露双侧颈上、颈下交感神经节及心下神经,对各部分逐一给以电刺激,采用生理多导仪分别记录刺激后不同时间点的心电图ST段(ElectroccardiogramST,ECGST)、左心室内压(LeftVentriclePressure,LVP)、左心室内压最大上升速率(Developedpressure/Developedtimemax,Dp/Dtmax)的变化情况。

结果: 刺激颈上交感节后ECGST、LVP、Dp/Dtmax均无变化;刺激颈下交感节和心下神经后LVP、Dp/Dtmax值明显下降,ECG出现明显的STT改变。

结论:下位颈椎病变可能更易刺激交感神经而出现心肌缺血性改变,并可影响心肌收缩性能。

[关键词]:颈椎病交感神经心功能实验研究

Influence of stimulating cervical sympathetic nerve on cardiac function in rabbits

Abstract:

Objective:To study effects of stimulating cervical sympathetic nerve on cardiac function so as to explore mechanism of cervical coronary heart diseases

Methods:In 30 rabbits,bilateral superior cervical ganglion(SCG),inferior cervical ganglion(ICG)and inferior cervical cardiac nerve(ICCN)were exposed and stimulated separately by electricity.Changes of index of cardiac function,such as Left ventricle pressure(LVP),developed pressure/developed time max (Dp/Dt_max)and ECG ST were recorded with physiologic instrument before and after stimulation.

Results:Stimulating SCG did not change LVP,Dp/Dt_max and ECG ST( P>0.05).After stimulating ICG and ICCN,LVP and Dp/Dt_max were descended obviously( P>0.01),besides ST segment and T wave depressed in ECG.With time,LVP,Dp/Dt_maxand ECG ST could ameliorate gradually.

Conclusion:Lesion occurred at inferior cervical vertebra was easy to stimulate sympathetic nerve,which could induce myocardial ischemia or abnormal cardiac contractility.

KEYWORDS:Cervical spondylosis Sympathetic nerve Cardiac function Experimental study

引用本文，请按以下格式著录参考文献：

中文格式:	齐越峰,张军,孙树椿,邵忠,庞伟.刺激颈交感神经对家兔心脏功能活动变化的影响[J].中国骨伤,2003,16(5):278~280
英文格式:	QI Yuefeng,ZHANG Jun,SUN Shuchun.Influence of stimulating cervical sympathetic nerve on cardiac function in rabbits[J].zhongguo gu shang / China J Orthop Trauma ,2003,16(5):278~280

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