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体外神经牵延器修复周围神经缺损的实验研究
Hits: 1779   Download times: 1136   Received:March 25, 2002    
作者Author单位UnitE-Mail
练克俭 LIAN Ke jian 解放军第一七五医院,福建 漳州 363000 The 175th Hospital of the PLA Fujian Zhangzhou , 363000, China  
洪加源 HONG Jia-yuan 解放军第一七五医院,福建 漳州 363000 The 175th Hospital of the PLA Fujian Zhangzhou , 363000, China  
翟文亮 ZHAI Wen-liang 解放军第一七五医院,福建 漳州 363000 The 175th Hospital of the PLA Fujian Zhangzhou , 363000, China  
丁真奇 解放军第一七五医院,福建 漳州 363000 The 175th Hospital of the PLA Fujian Zhangzhou , 363000, China  
康两期 解放军第一七五医院,福建 漳州 363000 The 175th Hospital of the PLA Fujian Zhangzhou , 363000, China  
郭林新 解放军第一七五医院,福建 漳州 363000 The 175th Hospital of the PLA Fujian Zhangzhou , 363000, China  
郭延杰 解放军第一七五医院,福建 漳州 363000 The 175th Hospital of the PLA Fujian Zhangzhou , 363000, China  
郭志民 解放军第一七五医院,福建 漳州 363000 The 175th Hospital of the PLA Fujian Zhangzhou , 363000, China  
期刊信息:《中国骨伤》2002年15卷,第12期,第727-728页
DOI:doi:10.3969/j.issn.1003-0034.yyyy.nn.zzz


目的:观察体外神经牵拉延长器修复兔周围神经缺损效果,为临床应用提供实验依据。

方法:健康成年家兔36只,造成右侧坐骨神经缺损模型,随机分为神经牵拉延长组(12只)、神经游离移植组(12只)和神经端端吻合组(12只)。术后每周观察动物一般情况,第12、16、20周行神经电生理测定,第20周观察组织学变化。

结果: 神经牵拉延长器组神经功能恢复情况与神经游离移植组无明显差别,优于神经端端吻合组。

结论:神经牵延器体外缓慢延长修复周围神经缺损是可行的。
[关键词]:周围神经  电生理学  组织学
 
Experimental study of nerve elongation apparatus for repair of defect of peripheral nerve in vitro
Abstract:

Objective:To observe the effect of nerve elongation apparatus in vitro to repair defect of peripheral nerve to provide the basis for the clinical application

Methods:The peripheral nerve defects were created in right sciatic nerve in 36 healthy rabbits,and they were divided randomly into nerve elongation group (n= 12),nerve graft group(n= 12) and end to end suture group(n= 12). After operation the general condition were observed every week and electro-physiologic testing were observed at 12th, 16th and 20th weeks and histo-pathlogical study were observed at 20th weeks.

Results:There was no statistical difference observed between nerve elongation group and nerve graft group, and their effect were excellent than end to end suture group.

Conclusion:The nerve elongation repairing of the peripheral nerve defect in vitro was effective and may be used clinically.
KEYWORDS:Peripheral nerves  Electrophysiology  Histology
 
引用本文,请按以下格式著录参考文献:
中文格式:练克俭,洪加源,翟文亮,丁真奇,康两期,郭林新,郭延杰,郭志民.体外神经牵延器修复周围神经缺损的实验研究[J].中国骨伤,2002,15(12):727~728
英文格式:LIAN Ke jian,HONG Jia-yuan,ZHAI Wen-liang.Experimental study of nerve elongation apparatus for repair of defect of peripheral nerve in vitro[J].zhongguo gu shang / China J Orthop Trauma ,2002,15(12):727~728
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