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大鼠胫骨骺板软骨细胞P物质的表达

Hits: 1974 Download times: 1279 Received:May 31, 2001

作者	Author	单位	Unit	E-Mail
李靖	LI Jing	第四军医大学西京医院全军骨科研究所,陕西西安710033	Xijing Hospital of the 4th Military University Shanxi Xian,710033
王全平	WANG Quan ping	第四军医大学西京医院全军骨科研究所,陕西西安710033	Xijing Hospital of the 4th Military University Shanxi Xian,710033
陶惠人	TAO Hui ren	第四军医大学西京医院全军骨科研究所,陕西西安710033	Xijing Hospital of the 4th Military University Shanxi Xian,710033
吕荣		第四军医大学西京医院全军骨科研究所,陕西西安710033	Xijing Hospital of the 4th Military University Shanxi Xian,710033
范宏斌		第四军医大学西京医院全军骨科研究所,陕西西安710033	Xijing Hospital of the 4th Military University Shanxi Xian,710033
王哲		第四军医大学西京医院全军骨科研究所,陕西西安710033	Xijing Hospital of the 4th Military University Shanxi Xian,710033

期刊信息：《中国骨伤》2002年15卷，第11期，第664-665页

DOI：doi:10.3969/j.issn.1003-0034.yyyy.nn.zzz

目的:研究P物质(SP)在大鼠胫骨骺板软骨细胞中的表达及其在长骨纵向生长中的意义。

方法:应用免疫组化技术检测8周龄大鼠胫骨骺板不同组织学层次软骨细胞的SP表达状况。

结果:骺板静止及增殖期软骨细胞未见SP免疫阳性染色,肥大区及钙化区软骨细胞可见SP免疫组化阳性染色。

结论:骺板肥大区及钙化区软骨细胞可以表达SP,提示SP在长骨的纵向生长中可能起调节作用。

[关键词]:胫骨骺软骨免疫组织化学

Expression of substances P in chondrocyte of rat’s tibia epiphyseal plate

Abstract:

Objective:To observe the expression of substances P(SP)in chondrocyte of rats tibia epiphyseal plate and its significance in longitudinal growth of long bone

Methods:To detect the expression of substances P(SP) in chondrocyte of 8 weeks old rats tibia epiphyseal plate of different histology level with immunohistochemical technique.

Results:The expression of SP were positive in maturing and calcifying chondrocyte and negative in static and proliferative phase.

Conclusion: SP were expressed in hypertrophic chondrocytes of epiphyseal plate.SP may regulate the bone modeling,espically in longitudinal growth of long bone.

KEYWORDS:Tibia Epiphyseal cartilage Immunohistochemistry

引用本文，请按以下格式著录参考文献：

中文格式:	李靖,王全平,陶惠人,吕荣,范宏斌,王哲.大鼠胫骨骺板软骨细胞P物质的表达[J].中国骨伤,2002,15(11):664~665
英文格式:	LI Jing,WANG Quan ping,TAO Hui ren.Expression of substances P in chondrocyte of rat’s tibia epiphyseal plate[J].zhongguo gu shang / China J Orthop Trauma ,2002,15(11):664~665

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