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中药对小白鼠骨骼肌切伤后再生影响的组织学观察

Hits: 2030 Download times: 1283 Received:October 24, 2001

作者	Author	单位	Unit	E-Mail
张建国	ZHANG Jian guo	三峡大学医学院解剖学教研室,湖北宜昌443003	The Three Gorges University Medical College Hubei Yichang 443003
孙强	SUN Qiang	三峡大学医学院解剖学教研室,湖北宜昌443003	The Three Gorges University Medical College Hubei Yichang 443003
朱建军	ZHU Jian jun	三峡大学医学院解剖学教研室,湖北宜昌443003	The Three Gorges University Medical College Hubei Yichang 443003
张兆祥		三峡大学医学院解剖学教研室,湖北宜昌443003	The Three Gorges University Medical College Hubei Yichang 443003

期刊信息：《中国骨伤》2002年15卷，第7期，第406-408页

DOI：doi:10.3969/j.issn.1003-0034.yyyy.nn.zzz

基金项目:三峡大学重点资助项目(项目编号:鄂三峡院科[2000]4号)

目的:探讨中药对骨骼肌切伤后再生的影响。

方法:昆明种小鼠50只,制作骨骼肌纵行切伤模型,口服中药为实验组,未用中药为对照组。术后分别于第2、3、5、7、10天处死动物。组织切片,HE染色,观察骨骼肌再生的情况,以评价中药对损伤骨骼肌再生的影响。

结果:实验组切口处肌卫星细胞激活;成肌细胞增殖、分化、融合以及肌管形成均快于对照组。

结论:中药可以促进骨骼肌切伤后的再生。

[关键词]:中医现代化骨骼肌再生

Histological study of regeneration effect of Chineses Traditional Medicine on incised wound on skeletal muscles in mice

Abstract:

Objective:To explore the effect and use of Chinese Medicinal Herbs(CMH)on regeneration of incised wound in skeletal muscles

Methods:Experimental trauma models of skeletal muscles with incised wound were made on 50 Kunming mice,half of them were given oral CMH as the experimental group,and the rest without CMH as control group.The mice were sacrificed successively at 2nd,3rd,5th,7th,10th day after operation.After tissue section,processing and HE staining,regeneration of skeletal muscles the effect of CMH on regeneration of skeletal muscles were observed.

Results:Activation of satellite cell,proliferation,differentiation,amalgamation of myoblast and formation of myotube of experimental group was faster than that of the control group.

Conclusion:The CMH could promote regeneration of skeletal muscles after incised wound.

KEYWORDS:Modernization(TCM) Skeletal muscles Regeneration

引用本文，请按以下格式著录参考文献：

中文格式:	张建国,孙强,朱建军,张兆祥.中药对小白鼠骨骼肌切伤后再生影响的组织学观察[J].中国骨伤,2002,15(7):406~408
英文格式:	ZHANG Jian guo,SUN Qiang,ZHU Jian jun.Histological study of regeneration effect of Chineses Traditional Medicine on incised wound on skeletal muscles in mice[J].zhongguo gu shang / China J Orthop Trauma ,2002,15(7):406~408

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