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消瘀接骨散促进骨折愈合的实验研究
Hits: 2035   Download times: 1692   Received:June 10, 1999  Revised:December 19, 1999  
作者Author单位UnitE-Mail
江树连 JIANG Shulian 安徽中医学院第一附属医院,安徽合肥230031 The 1st Hospital of Anhui TCMC,Anhui Hefei,230031  
丁锷 DING E 安徽中医学院第一附属医院,安徽合肥230031 The 1st Hospital of Anhui TCMC,Anhui Hefei,230031  
李保泉 LI Baoquan 安徽中医学院第一附属医院,安徽合肥230031 The 1st Hospital of Anhui TCMC,Anhui Hefei,230031  
曹日隆 安徽中医学院第一附属医院,安徽合肥230031 The 1st Hospital of Anhui TCMC,Anhui Hefei,230031  
期刊信息:《中国骨伤》2000年13卷,第12期,第720-721页
DOI:doi:10.3969/j.issn.1003-0034.yyyy.nn.zzz


目的:验证消瘀接骨散促进骨折愈合的疗效和探讨其治疗机理。

方法:选用40只健康雄性家兔,做双侧桡骨中、下1/3人工骨折模型,随机分为实验组外敷消瘀接骨散和对照组不敷药,术后7天、14天、22天和32天分别处死动物,取桡骨标本X线片检查、作生物力学测试和称取骨痂干重。

结果:实验组的X线平片显示骨折修复优于对照组,而且生物力学性能和骨痂干重均显着高于对照组(P<0.05或P<0.01).

结论:消瘀接骨散能缩短骨折愈合过程和提高骨折愈合质量。
[关键词]:活血祛瘀药(剂)  骨折  开放性  外用药(中药)
 
Experimental Studies on the Influence of External Application of Xiao Yu Jie Gu San on Fracture Healing
Abstract:

objective: To verify the therapeutic effect of Xiao Yu Jie Gu San (XYJGS) on fracture healing and explore its mechanism.

Methods:Standard fracture models between midand lower 1/3 of the radius bilaterally were made in 40 male rabbits.They were divided randomly into test and control groups.XYJGS was externally applied only to the test group.On the 7th,14th,22nd,and 32nd days after operation,the animals were sacrificed respectively and the radius specimen were taken,X ray films were taken,biomechanical property tested and the weight of dry callus measured.

Results: The X ray films suggested that the fracture healing of test group were better than that of the control’s,while the biomechanical property test and the weight of dry callus of test group were higher significantly than that of control group (P<0 05或P<0 01).

Conclusion: XYJGS is able to shorten the fracture healing period and improve the fracture healing quality.
KEYWORDS:Blood-activating stasis-removing drugs(agents) Fractures  open External application drugs(chinese herb)
 
引用本文,请按以下格式著录参考文献:
中文格式:江树连,丁锷,李保泉,曹日隆.消瘀接骨散促进骨折愈合的实验研究[J].中国骨伤,2000,13(12):720~721
英文格式:JIANG Shulian,DING E,LI Baoquan.Experimental Studies on the Influence of External Application of Xiao Yu Jie Gu San on Fracture Healing[J].zhongguo gu shang / China J Orthop Trauma ,2000,13(12):720~721
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