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中药对模拟颈神经炎大鼠血浆前列腺素E₂作用的放免测定观察

Hits: 2066 Download times: 1272 Received:July 05, 1999

作者	Author	单位	Unit	E-Mail
张军	ZHANG Jun	中国中医研究院骨伤科研究所,北京100700	Institute of Orthopaedics and Traumatology,China Academy of TCM Beijing,100700
孙树椿	SUN Shu chun	中国中医研究院骨伤科研究所,北京100700	Institute of Orthopaedics and Traumatology,China Academy of TCM Beijing,100700

期刊信息：《中国骨伤》2000年13卷，第5期，第273-275页

DOI：doi:10.3969/j.issn.1003-0034.yyyy.nn.zzz

目的:观察中药颈椎Ⅰ号对模拟颈神经根炎大鼠血浆中PGE₂含量的影响。

方法:将72只模拟颈神经根炎Wistar大鼠随机分为四组:颈椎Ⅰ号中剂量组、颈椎Ⅰ号高剂量组、颈复康组及空白对照组,分别给予颈椎Ⅰ号中剂量、高剂量、颈复康及凉开水,于造模后3天、7天、14天,取血浆进行PGE₂含量的放射免疫测定。

结果:颈椎Ⅰ号中剂量、高剂量可以明显减轻模拟鼠血浆中PGE₂含量。

结论:颈椎Ⅰ号对模拟颈神经根炎具有良好的抗炎功效。

[关键词]:中草药颈神经根炎放射免疫测定

Radioimmunoassay Observation of the Effects of Chinese Medicinal Herbs on PGE₂ in the Plasma of Rat Model Mimicking Cervical Radiculitis

Abstract:

Objective:To determine the effects of Jingzhui NoI(JZ I)on PGE₂ in the plasma of mimic cervical radiculitis in rats

Methods:72 mimic cervical radiculitis Wistar rats were divided into 4 groups randomly:moderate dose group of JZ I,high dose group of JZ I,Jingfukang group and control group JZ I of moderate dose,JZ I of high dose,Jingfukang and water were given to the rats seperately PGE₂ was determinated by radioimmunoassay at 3,7,14 days after animal models had been made

Results:JZ I of moderate and high dose could significantly decrease the content of PGE₂ in the blood.

Conclusion:JZ-I can inhibit inflammation of the mimic cervical radiculitis.

KEYWORDS:Chinese medicinal herbs Neck Radiculitis Radioallergosorbent test

引用本文，请按以下格式著录参考文献：

中文格式:	张军,孙树椿.中药对模拟颈神经炎大鼠血浆前列腺素E₂作用的放免测定观察[J].中国骨伤,2000,13(5):273~275
英文格式:	ZHANG Jun,SUN Shu chun.Radioimmunoassay Observation of the Effects of Chinese Medicinal Herbs on PGE₂ in the Plasma of Rat Model Mimicking Cervical Radiculitis[J].zhongguo gu shang / China J Orthop Trauma ,2000,13(5):273~275

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