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兔椎间节段固定区软骨终板组织病理学变化

Hits: 1766 Download times: 1104 Received:September 21, 1997

作者	Author	单位	Unit	E-Mail
赤仁杰	Chi Renjie	沈阳医学院附属中心医院,辽宁沈阳110024	Central Hospital Affiliated to Shenyang Medical College, Liaoning Province shen yang110024
张忠枢	Zhang Zhongshu	沈阳医学院附属中心医院,辽宁沈阳110024	Central Hospital Affiliated to Shenyang Medical College, Liaoning Province shen yang110024
张焱	Zhang Yan	沈阳医学院附属中心医院,辽宁沈阳110024	Central Hospital Affiliated to Shenyang Medical College, Liaoning Province shen yang110024
王海义		中国医科大学附属第二临床医院,辽宁沈阳

期刊信息：《中国骨伤》1999年12卷，第6期，第10-12页

DOI：doi:10.3969/j.issn.1003-0034.yyyy.nn.zzz

目的:明确脊椎节段固定区软骨终板的变化与脊椎内固定术后并发症二者之间的关系。

方法:制做新西兰兔脊椎节段内固定模型24只为实验组,分别于术后3个月,6个月进行固定区椎间盘软骨终板的形态学观察,并与8只对照组兔比较。

结果:实验组兔固定区软骨终板呈现退变趋势,椎间盘发生退变。

结论:这种改变将对脊椎内固定产生不利影响。提出减少脊椎内固定节段,固定区椎间盘切除并植骨是防止术后并发症产生的一种有效方法。

[关键词]:兔脊椎内固定软骨终板退变

Histopathological Changes of Cartilage End plate in Rabbits after Spinal Fixation

Abstract:

Objective: To make clear the relationship between the changes of cartilage end plate in the fixed segments and the complications after internal fixation of spine

Methods: In experimental group, intersegmental fixation of lumbar spine were made in 24 adult New Zealand rabbits, and after 3 and 6 months the changes of cartilage end plate in fixed segments were examined with LM and TEM, and the results were compared with the structures of cartilage end plate in 8 controlled rabbits

Results: Degenerative changes were found in the cartilage end plates and intervertebral discs

Conclusion: The degenerative changes in cartilage end plates and discs would induce harmful effect on spinal fixation Decreasing the fixed segments, resecting the discs in the fixed region and grafting bone will be the effective method for avoiding the postoperative complications.

KEYWORDS:Rabbit Internal fixation of spine Cartilage end plate Degeneration

引用本文，请按以下格式著录参考文献：

中文格式:	赤仁杰,张忠枢,张焱,王海义.兔椎间节段固定区软骨终板组织病理学变化[J].中国骨伤,1999,12(6):10~12
英文格式:	Chi Renjie,Zhang Zhongshu,Zhang Yan.Histopathological Changes of Cartilage End plate in Rabbits after Spinal Fixation[J].zhongguo gu shang / China J Orthop Trauma ,1999,12(6):10~12

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