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药物治疗对清创术后血清C─反应蛋白变化的观察
Hits: 1886   Download times: 1095   Received:December 02, 1996  Revised:October 27, 1997  
作者Author单位UnitE-Mail
刘保平 Liu Baoping 同济医科大学附属协和医院,武汉430022 Xiehe Hospital Tong ji Medical University Wuhan 430022  
沈霖 Shen Lin 同济医科大学附属协和医院,武汉430022 Xiehe Hospital Tong ji Medical University Wuhan 430022  
杨家玉 Yang Jiayu 同济医科大学附属协和医院,武汉430022 Xiehe Hospital Tong ji Medical University Wuhan 430022  
高兰 同济医科大学附属协和医院,武汉430022 Xiehe Hospital Tong ji Medical University Wuhan 430022  
叶嗣颖 同济医科大学微生物学教研室  
期刊信息:《中国骨伤》1998年11卷,第3期,第3-5页
DOI:doi:10.3969/j.issn.1003-0034.yyyy.nn.zzz


目的:观察药物治疗对清创术后血清C──反应蛋白的变化。

方法:清创术后患者分为2组:A组采用中药一盘珠汤加青霉素钠盐治疗,B组单用青霉素钠盐治疗,对比两组的治疗效果。在治疗过程中观察体温、白细胞计数和血清C──反应蛋白的变化。

结果:治疗3天、5天和7天后,两组的血清C──反应蛋白均有不同程度的下降,但A组显着低于B组;而体温、白细胞计数在术后7天,两组才显示差异。两组术后感染发生率分别为8.3%和20%.

结论:清创术后患者在应用抗生素的同时加用中药治疗,可降低感染的发生率。血清C──反应蛋白的监测有助于早期发现感染及其某些药物疗效的观察。
[关键词]:清创术后  C─反应蛋白  中医药疗法
 
Effects of Pharmaceutical Therapy on the Changes of post-debridement Serum C-Reactive Protein
Abstract:

Aim: To observe the effects of pharmaceutical therapy on the post-debridement serum Creactive protein.

Methods: There were 2 groups for treatment: group A treated with Chinese traditional medicine, Yi Pan Zhu decoction plus sodium penicillin, and group B only with sodium penicillin. For the comparison of the therapeutic effects between them, the body temperature, WBC count and serum C-reac- tive protein, in the course of treatment, had been examined to find out the difference between these two groups.

Results: 3, 5 and 7 days after the treatment, the contents of serum C-reactive protein were decreased to various degree in these two groups, and the content of serum C-reactive protein in group A was significantly lower than that in group B. But the differences of temperature and WBC count between these two groups were appeared 7 days after operation. The postoperative infection rate was 8. 3% in group A and 20% in group B.

Conclusion: The application of the antibiotics plus traditional Chinese medicine can decrease the postoperative infection rate in the post-debridement patients. The change of serum C-reactive protein is beneficial to early finding of infection and observation of therapeutic effect of some drugs.
KEYWORDS:Post-debridement  Serum C-reactive protein  Treatment of traditional Chinese medicine
 
引用本文,请按以下格式著录参考文献:
中文格式:刘保平,沈霖,杨家玉,高兰,叶嗣颖.药物治疗对清创术后血清C─反应蛋白变化的观察[J].中国骨伤,1998,11(3):3~5
英文格式:Liu Baoping,Shen Lin,Yang Jiayu.Effects of Pharmaceutical Therapy on the Changes of post-debridement Serum C-Reactive Protein[J].zhongguo gu shang / China J Orthop Trauma ,1998,11(3):3~5
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