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止痛消肿贴膏抗炎作用研究
Hits: 1952   Download times: 1180   Received:October 22, 1996    
作者Author单位UnitE-Mail
杜宁 Du Ning 上海第二医科大学附属瑞金医院,200025 Ruijin Hospital, Affiliated to Shanghai Second Medical University 200025  
符诗聪 Fu Shicong 上海第二医科大学附属瑞金医院,200025 Ruijin Hospital, Affiliated to Shanghai Second Medical University 200025  
史炜镔 Shi Weibin 上海第二医科大学附属瑞金医院,200025 Ruijin Hospital, Affiliated to Shanghai Second Medical University 200025  
钱宵霞 上海卫生材料厂  
马秀凤 上海卫生材料厂  
杨琦 上海第二医科大学数学教研室  
期刊信息:《中国骨伤》1998年11卷,第2期,第47-49页
DOI:doi:10.3969/j.issn.1003-0034.yyyy.nn.zzz
以中药牡丹皮的有效成分-牡丹酚为主要原料制成的止痛消肿贴膏,仍保持了牡丹酚抗炎的作用,能够有效地抑制大鼠足跖角菜胶所致急性炎症和大鼠亚急性炎症(肉芽肿).同阳性对照药巴布剂关节镇痛膏、麝香解痛膏及扶他林乳胶剂相比,具有显着差异性。同时其高剂量组与低剂量组比较,抗炎作用显着提高。说明:止痛消肿贴膏,尤其是高剂量者,是一种较好的抗炎外用药膏,其作用一定程度上,优于上述阳性对照药物。
[关键词]:止痛消肿贴膏  牡丹酚  抗炎
 
Experimental Study of Anti-inflammatory Effect of Zhi Tong Xiao Zhong Tie Gao
Abstract:Zhi Tong Xiao Zhong Tie Gao (ZTXZTG), with the main component paeonal, is maintaining the same anti-in- flammatory effect of paeonol. In experiments on rats, the results showed that ZTXZTG can efficiently inhibit the acute inflammation and subacute inflammation (granuloma) induced resistively by carragenin and cotten ball, and there are significant differences in comparison with the effects of the positive controls (Ba Bu Ji Guan Jie Zhen Tong Gao, She Xiang Jie Tong Gao, and Voltaren emulgel), and the anti-inflammatory effect of high dose of ZTXZTG is significantly higher than that of the low dose. All above indicated that ZTXZTG, especially its high dose plaster, is an effective anti-inflammatory plaster and is superior to above mentioned positive controls to a certain extent.
KEYWORDS:Zhi Tong Xiao  ZhongTie Gao  Paeonol  Anti-inflammation
 
引用本文,请按以下格式著录参考文献:
中文格式:杜宁,符诗聪,史炜镔,钱宵霞,马秀凤,杨琦.止痛消肿贴膏抗炎作用研究[J].中国骨伤,1998,11(2):47~49
英文格式:Du Ning,Fu Shicong,Shi Weibin.Experimental Study of Anti-inflammatory Effect of Zhi Tong Xiao Zhong Tie Gao[J].zhongguo gu shang / China J Orthop Trauma ,1998,11(2):47~49
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