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补肾中药对骨质疏松大鼠骨骼的影响

Hits: 2166 Download times: 1130 Received:June 06, 1996

作者	Author	单位	Unit	E-Mail
宋献文	Song Xianwen	上海铁道大学附属甘泉医院,200065	Ganquan Hospital of Shanghai Railway University, Shanghai 200065
石印玉	Shi Yinyu	上海中医药大学附属曙光医院
沈培芝	Shen Peizhi	上海中医药研究院骨伤科研究所
张英		上海中医药研究院骨伤科研究所

期刊信息：《中国骨伤》1997年10卷，第5期，第13-14页

DOI：doi:10.3969/j.issn.1003-0034.yyyy.nn.zzz

本实验以股骨密度、抗弯强度和股骨骨小梁体积为指标,观察补肾中药对骨质疏松大鼠骨骼的影响。用卵巢切除的方法建立大鼠骨质疏松模型,然后对模型分别给乙烯雌酚或中药治疗3个月后发现,乙烯雌酚或中药治疗可以阻止股骨密度,抗弯强度和胫骨骨小梁体积的下降,但两种药物均不能使已经下降的股骨密度、抗弯强度和胫骨骨小梁体积升高。这一结果提示：补肾中药对骨质疏松大鼠有防治作用。

[关键词]:骨质疏松骨中草药大鼠

Effect of Chinese Kidney-tonifying Drug on Bone of Osteoporotic Rat

Abstract:The effect of Chinese kidney-tonifying druges on bones of osteoporotic rats were investigated by detecting bone mineral density(BMD),resistance bending strength(RBS) and bone trabecular volume(BTV).Femal rats were ovariectomized to build the model of osteoporosis, and then treated with Chinese drugs and stilbestrol respectively for 3 months. The results showed that both Chinese drugs and stilbestrol prevented the BMD. RBS and BTV from further declining in osteoporotic rats; but could not raise the BMD, RBS and BTV that had declined. The writers suggested that Chinese drugs with kidney-tonifying action might prevent and treat rats' osteopotosis.

KEYWORDS:Osteoporosis Bone Chinese drug Rat

引用本文，请按以下格式著录参考文献：

中文格式:	宋献文,石印玉,沈培芝,张英.补肾中药对骨质疏松大鼠骨骼的影响[J].中国骨伤,1997,10(5):13~14
英文格式:	Song Xianwen,Shi Yinyu,Shen Peizhi.Effect of Chinese Kidney-tonifying Drug on Bone of Osteoporotic Rat[J].zhongguo gu shang / China J Orthop Trauma ,1997,10(5):13~14

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