| 骨松Ⅱ号对去卵巢兔骨代谢影响的骨计量学研究 |
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Received:December 28, 1995 Revised:May 23, 1996
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| 作者 | Author | 单位 | Unit | E-Mail |
| 史炜镔 |
Shi Weibi |
上海第二医科大学上海市伤骨科研究所,200025 |
Shanghai Institute of Traumatology and Orthopedics, Shanghai Second Medical University 200025 |
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| 杜宁 |
Du Ning |
上海第二医科大学上海市伤骨科研究所,200025 |
Shanghai Institute of Traumatology and Orthopedics, Shanghai Second Medical University 200025 |
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| 符诗聪 |
Fu Shicong |
上海第二医科大学上海市伤骨科研究所,200025 |
Shanghai Institute of Traumatology and Orthopedics, Shanghai Second Medical University 200025 |
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| 王济纬 |
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上海第二医科大学上海市伤骨科研究所,200025 |
Shanghai Institute of Traumatology and Orthopedics, Shanghai Second Medical University 200025 |
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| 曲克服 |
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上海第二医科大学上海市伤骨科研究所,200025 |
Shanghai Institute of Traumatology and Orthopedics, Shanghai Second Medical University 200025 |
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| 李国衡 |
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上海第二医科大学上海市伤骨科研究所,200025 |
Shanghai Institute of Traumatology and Orthopedics, Shanghai Second Medical University 200025 |
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| 期刊信息：《中国骨伤》1997年10卷，第3期，第11-14页 |
| DOI：doi:10.3969/j.issn.1003-0034.yyyy.nn.zzz |
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| 运用骨计量学观察了中药膏极Ⅱ号对兔切除卵巢诱导的骨质疏松症实验模型的影响,并与尼尔雌醇进行对照。结果显示：骨松Ⅱ号组与尼尔雌醇组在BV/TV、OV/BV、OBI、dLs/BS和BFR(T)等参数方面明显高于造模组和/或正常对照组,骨松Ⅱ号组OV/BV、OB％以及OBI等参数较尼尔雌醇级明显升高。提示：骨松Ⅱ号能增加成骨细胞数量,以产生较多骨质,使骨疏松症模型兔的骨代谢恢复正平衡,达到防治骨质疏松症的目的,其作用一定程度上优于尼尔雌醇。 |
| [关键词]:骨松Ⅱ号 卵巢摘除 骨代谢 骨计量学 |
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| Histomorphometric Study on the Effect of Gusong Ⅱ on Bong Turnover in Ovariectomized Rabbits |
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| Abstract:The effects of gusong Ⅱ on experimental postmenopausal osteoporosis in ovariectomized New Zealand white rabbits were assessed histomorpphometrically and compared with that of nylestriol.The results demonstrated that BV/TV, OBI, dLs/BS and BFR increased in both group A (OVX- Gusong Ⅱ) and group D (OVX-nylestriol ) as compared with group B (OVX) and/or group C (Sham). Group A showed a significant increase of OV/13V,OB% and UBI as compared with group D. It indicated that Gusong Ⅱ can stimulate the recruitment and/or proliferation of osteoblasts to produce more bone matrix,converting the bone turnover of OVX rabbits to a positive balance. This effect may be superior to that of nylestriol to some extent. |
| KEYWORDS:Chinese herb Gusong Ⅱ Ovariectomy New Zealand white rabbit Bone histomorphometry |
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| 引用本文，请按以下格式著录参考文献： |
| 中文格式: | 史炜镔,杜宁,符诗聪,王济纬,曲克服,李国衡.骨松Ⅱ号对去卵巢兔骨代谢影响的骨计量学研究[J].中国骨伤,1997,10(3):11~14 |
| 英文格式: | Shi Weibi,Du Ning,Fu Shicong.Histomorphometric Study on the Effect of Gusong Ⅱ on Bong Turnover in Ovariectomized Rabbits[J].zhongguo gu shang / China J Orthop Trauma ,1997,10(3):11~14 |
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