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纤维结合蛋白在创伤愈合中的动态研究──“偎脓长肉”作用机制研究之四

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作者	Author	单位	Unit	E-Mail
李秀兰	Li Xiu-lan	天津骨科研究所	Tianjin Institute of Orthopaedics 300211
师宜键	Shi Yi-jina	天津骨科研究所	Tianjin Institute of Orthopaedics 300211
徐尔真	Xu Er-zhen	南开大学生物系
赵凤仪	Zhao Feng-yi	天津骨科研究所	Tianjin Institute of Orthopaedics 300211

期刊信息：《中国骨伤》1995年8卷，第4期，第10-12页

DOI：doi:10.3969/j.issn.1003-0034.yyyy.nn.zzz

本文选用32只家兔,制造感染创面模型。观察在创伤愈合中血浆纤维结合(Fn)和创面Fn含量的动态变化,以及外用中药对其影响。实验结果表明,血浆Fn与创面愈合时间呈显着性正相关。创面Fn则为显着性负相关。外用中药可使创面Fn明显增高,且与对照组有显着性差异(P<0.01).提示,外用中药是创面Fn的良好调节剂；在创面愈合中可提高创面Fn含量,进而增强局部抗感染和损伤修复能力而达到加速创伤愈合。

[关键词]:外用中药纤维结合蛋白创伤愈合

Motive study of fibrin binding protein in wound healing-Mechanism of Wei Nong Zhang Rou(IV)

Abstract:Thirty-two rabbits were selected to make infected wound surface models to observe the motive changes of fibrin binding protein and contents of it at the wound surface, and the influence of external application of Chinese herbs. The results of experiment indicated that there were positive correlation of fibrin binding protein and wound surface healing time, but there were evident negative correlation with wound fibrin. Application of Chinese herbs can elevate prominently in wound surface fibrin, there were significant difference(P<0.01) as compared with the control. This suggested that external application of Chinese herbs is a good regulation of wound surface fibrin. It can elevate contents of wound surface fibrin, increase local anti-infective and repairing ability of injury and reach the aim of accerelate wound healing.

KEYWORDS:External application Chinese herb Fibrin binding protein Wound healing

引用本文，请按以下格式著录参考文献：

中文格式:	李秀兰,师宜键,徐尔真,赵凤仪.纤维结合蛋白在创伤愈合中的动态研究──“偎脓长肉”作用机制研究之四[J].中国骨伤,1995,8(4):10~12
英文格式:	Li Xiu-lan,Shi Yi-jina,Xu Er-zhen,Zhao Feng-yi.Motive study of fibrin binding protein in wound healing-Mechanism of Wei Nong Zhang Rou(IV)[J].zhongguo gu shang / China J Orthop Trauma ,1995,8(4):10~12

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