| 创面愈合中巨噬细胞功能与异质性动态研究──“偎脓长肉”作用机制研究之二 |
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Received:August 19, 1994 Revised:November 21, 1994
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| 期刊信息：《中国骨伤》1995年8卷，第2期，第8-11页 |
| DOI：doi:10.3969/j.issn.1003-0034.yyyy.nn.zzz |
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| 本文以家兔制作感染创面动物模型。皮下埋入改良schiiling不锈钢管,获取创面渗出液,收集创面细胞。采用Wright-Giemsa染色创面细胞,发现在创面愈合中外用中药组创面渗出液中巨噬细胞(Mφ)数量多,且游走型Mφ多于常驻型Mφ,与对照组比较呈显着性差异。组织化染色发现Mφ细胞内酸性磷酸酶(ACP)和糖代谢的限速酶琥珀酸脱氢酶(SDH),在创面愈合中与对照组均有极显着差异。提示外用中药可激活创面细胞提高细胞内酶活性,对促进创面愈合起重要作用。 |
| [关键词]:创面愈合 巨噬细胞功能 酸性磷酸酶 琥珀酸脱氢酶 |
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| Phagocytic function and heterogeinicitic motive studies of surface wound healing──Studies on the mechanism of Wei Nong Zhang Rou (2) |
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| Abstract:Rabbit infected surface wound models were prepared. Wound exudation and surface wound cells were collected with modified Schilling stainless steel tube embedded in the hypoderm. The surface wound cells were statined with Wright-Giemsa statins. It was found that number of macrocytes (M) increased during process of the surface wound healing in external application of Chinese drug group, besides the wandering macrocytes were more than permanent ones. The differences were singificant statistically. Through histochemical staining, there were very significantdifference of the acid-phosphatase (AcP) and sugar metabolic rate-limiting succinate dehydrogenase (SDH) between surface wound healing and control group. It is suggested that external application of Chinese medicine can activate surface wound cells and elevate intracellular enzymic activity. It plays an important role in promoting surface wound healing. |
| KEYWORDS:Surface wound healing Macrocytes Acid phosphatase Succinate dehydrogenase |
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| 引用本文，请按以下格式著录参考文献： |
| 中文格式: | 李秀兰,徐尔真,师宜健,赵凤义.创面愈合中巨噬细胞功能与异质性动态研究──“偎脓长肉”作用机制研究之二[J].中国骨伤,1995,8(2):8~11 |
| 英文格式: | Li xiu-lan,Xu Er-zhen,Shi Yi-jian,Zhao Feng-yi.Phagocytic function and heterogeinicitic motive studies of surface wound healing──Studies on the mechanism of Wei Nong Zhang Rou (2)[J].zhongguo gu shang / China J Orthop Trauma ,1995,8(2):8~11 |
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