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“骨宝丸”防治佝偻病的实验研究

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作者	Author	单位	Unit	E-Mail
陈燕平	Chen Yanping	中国中医研究院骨伤科研究所	Institute of Orthopoedics & Traumatology,China Academy of Traditional Chinese Medicine 100700
陈训华	Chen Xunhua	中国中医研究院骨伤科研究所	Institute of Orthopoedics & Traumatology,China Academy of Traditional Chinese Medicine 100700
薛延		北京积水潭医院生化研究室
龚翠红		中国中医研究院骨伤科研究所	Institute of Orthopoedics & Traumatology,China Academy of Traditional Chinese Medicine 100700
苗燕玲		中国中医研究院骨伤科研究所	Institute of Orthopoedics & Traumatology,China Academy of Traditional Chinese Medicine 100700
邱明才		天津医学院附属医院内分泌研究所

期刊信息：《中国骨伤》1994年7卷，第5期，第5-6页

DOI：doi:10.3969/j.issn.1003-0034.yyyy.nn.zzz

本文观察了佝偻病大鼠在用中药“骨宝丸”治疗前后血清钙、磷、碱性磷酸酶、25羟基维生素D3及骨组织形态学和骨计量学的变化,并与维生素D3进行了比较。结果表明：“骨宝丸”防治佝偻病有效,特别是在提高血钙、血磷和降低血碱性磷酸酶以及促进类骨质矿化方面效果显着,但其作用机理与维生素D3不同。

[关键词]:佝偻病骨宝丸预防与治疗

Experimental study on Gu Bao Wan in treating rachitis

Abstract:In this article,changes of serum calcium.phosphorus.alkaline phosphatase,25-hydroxy-vitamin D3,bone tissue morphology and bone metrology were observed in treating rachitic rats with Chinese medicine Gu Bao Wan pre-and post-treatment and they were compared with Vitamin D3.The results indicated that Gu Bao Wan is effective in the prevention and treatment of rachitis,especially it has prominent effects in the elevation of serum calcium,phosphorus,and decreasing of serum alkaline phosphatase and in the promotion of mineralization of osteoid.But it is different from the mechanism of Vitamin D3.

KEYWORDS:Rachitis Gu Bao Wan Prevention and treatment

引用本文，请按以下格式著录参考文献：

中文格式:	陈燕平,陈训华,薛延,龚翠红,苗燕玲,邱明才.“骨宝丸”防治佝偻病的实验研究[J].中国骨伤,1994,7(5):5~6
英文格式:	Chen Yanping,Chen Xunhua.Experimental study on Gu Bao Wan in treating rachitis[J].zhongguo gu shang / China J Orthop Trauma ,1994,7(5):5~6

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