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壮骨素促进骨折愈合的实验研究

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作者	Author	单位	Unit	E-Mail
夏志道	Xia Zhi-dao	湖北武汉同济医科大学附属协和医院骨科
房世源	Fang Shi-yuan	中国中医研究院骨伤科研究所	Institute of Orthopaedics and Traumatology, China Academy of Traditional Chinese Medicine, Beijing 100700
常超英		中国中医研究院骨伤科研究所	Institute of Orthopaedics and Traumatology, China Academy of Traditional Chinese Medicine, Beijing 100700
王来鸿		中国中医研究院骨伤科研究所	Institute of Orthopaedics and Traumatology, China Academy of Traditional Chinese Medicine, Beijing 100700
蒋位庄		中国中医研究院骨伤科研究所	Institute of Orthopaedics and Traumatology, China Academy of Traditional Chinese Medicine, Beijing 100700
魏兑民		浙江省中医药研究院
吴非		贵阳中医学院骨伤科研究所

期刊信息：《中国骨伤》1994年7卷，第1期，第7-9页

DOI：doi:10.3969/j.issn.1003-0034.yyyy.nn.zzz

壮骨素及当归、川芎嗪注射液联用,用于家兔桡骨标准骨折模型的治疗。通过体重观察、X片和骨痂切片组织形态计量学分析,结果显示：单纯使用“壮骨素”灌胃治疗组比空白对照组更高的X片评分(P<0.001)、更高的外骨痂及有效骨痂密度,细胞水平显示活跃的破骨细胞活动(0.01

[关键词]:壮骨素骨折愈合家兔实验研究

Experimental study on Zhuang Gu Su(ZGS) in promoting fracture healing

Abstract:Standard fracture model was produced in Rabbits which were divided into three groups to stury the effects of ZGS(abstracted from Bombyx mori L) and ZGS combined with injections of Angelica sinesis and Lingusticum wallichii, traditional herbs for treating the fracture.Thuough observation of body weight changes, the X -ray films, and the histomorphormetric analysis of callus section,the results indicated that there were higher X-ray skating(P<0.001), more external callus and effective callus density, more osteoclast activity(0.01<P<0.05)in ZGS group than the control.In the ZGS combined with promoting blood circulation and removing stasis group ,the results showed early controlling of weight reducing in fractured animals (P<0.01) as compared with control, more higher X -ray film skating(P<0.001), mineralization callus density (0.01<P<0.05), osteoclast activity observing surface (0.01 <P<0.05) and osteoclast index (P<0.001),and the sec-tion showed betttr callus remodeling.

KEYWORDS:Zhuang Gu Su fracture healing rabbit experimental study

引用本文，请按以下格式著录参考文献：

中文格式:	夏志道,房世源,常超英,王来鸿,蒋位庄,魏兑民,吴非.壮骨素促进骨折愈合的实验研究[J].中国骨伤,1994,7(1):7~9
英文格式:	Xia Zhi-dao,Fang Shi-yuan.Experimental study on Zhuang Gu Su(ZGS) in promoting fracture healing[J].zhongguo gu shang / China J Orthop Trauma ,1994,7(1):7~9

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