| 富血小板血浆关节腔注射联合冲击波治疗距骨骨软骨损伤的疗效观察 |
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投稿时间：2023-11-08
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| 作者 | Author | 单位 | Address | E-Mail |
| 刘英 |
LIU Ying |
四川省骨科医院放射科, 四川 成都 610041 |
Department of Radiology, Sichuan Orthopaedic Hospital, Chengdu 610041, Sichuan, China |
229562656@qq.com |
| 刘太 |
LIU Tai |
四川省骨科医院筋伤科, 四川 成都 610041 |
Department of Tendon Injury, Sichuan Orthopaedic Hospital, Chengdu 610041, Sichuan, China |
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| 付婷婷 |
FU Ting-ting |
四川省骨科医院康复科, 四川 成都 610041 |
Department of Rehabilitation, Sichuan Orthopaedic Hospital, Chengdu 610041, Sichuan, China |
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| 陈君蓉 |
CHEN Jun-rong |
四川省骨科医院放射科, 四川 成都 610041 |
Department of Radiology, Sichuan Orthopaedic Hospital, Chengdu 610041, Sichuan, China |
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| 李旭雪 |
LI Xu-xue |
四川省骨科医院放射科, 四川 成都 610041 |
Department of Radiology, Sichuan Orthopaedic Hospital, Chengdu 610041, Sichuan, China |
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| 期刊信息：《中国骨伤》2024年，第37卷，第12期，第1224-1228页 |
| DOI：10.12200/j.issn.1003-0034.20230762 |
| 基金项目:四川省医学会骨科(尚安通)专项科研课题(编号:2021SAT18) |
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中文摘要:
目的: 探讨富血小板血浆(platelet-rich plasma,PRP)关节腔注射联合体外冲击波(extracorporeal shock wave therapy,ESWT)治疗Ⅱa型距骨骨软骨损伤(osteochondral lesion of the talus,OLT) 的临床疗效。
方法: 自2022年1月至2022年6月采用PRP关节腔注射联合ESWT治疗45例Ⅱa型OLT患者,其中男29例,女16例;年龄18~63(37.7±10.3)岁;病程6~20(13.3±4.8)个月。分别于治疗前及治疗后3、6个月,采用美国足与踝关节协会(American Orthopaedic Foot and Ankle Society,AOFAS)踝与足评分、疼痛视觉模拟评分(visual analogue scale,VAS)、软骨损伤体积及骨髓水肿体积评估患者踝关节功能及距骨骨软骨恢复情况。
结果: 所有患者获得至少6个月的随访。所有患者未出现并发症。AOFAS评分分别由治疗前的(68.3±3.6)分提高至治疗后3、6个月的(83.7±3.2)、(90.8±2.2)分(P<0.05);VAS由治疗前的(5.2±1.2)分降至治疗后3、6个月的(3.2±0.8)、(1.9±1.2)分(P<0.05);软骨及软骨下骨损伤体积由治疗前的(71.0±42.5) mm3降至治疗后3、6个月的(50.6±31.5)、(36.5±27.3) mm3(P<0.05);骨髓水肿体积由治疗前的(1 182.7±675.1) mm3降至治疗后3、6个月的(656.1±455.1)、(382.1±485.6) mm3(P<0.05)。
结论: PRP关节腔内注射联合ESWT治疗Ⅱa型OLT可减轻患者临床症状,有效改善关节功能,促进软骨修复和骨髓水肿吸收。 |
| 【关键词】距骨 软骨损伤 磁共振 骨髓水肿 |
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| Therapeutic effect of joint injection of platelet-rich plasma combined with shock wave on osteochondral injury of talus |
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ABSTRACT
Objective To explore clinical efficacy of platelet rich plasma (PRP) injection combined with extracorporeal shock wave therapy (ESWT) in treating osteochondral lesion of talus (OLT) with typeⅡa.
Methods From January 2022 to June 2022,45 patients with typeⅡa OLT were treated with PRP arthroscopic injection combined with ESWT,including 29 males and 16 females; aged from 18 to 63 years old with an average of(37.7±10.3) years old;the courses of disease ranged from 6 to 20 with an average of (13.3±4.8) months. American Foot and Ankle Association ankle and foot (AOFAS) score,visual analogue scale (VAS),cartilage injury volume and bone marrow edema volume were evaluated for ankle joint function and osteochondral recovery of talus before treatment,3 and 6 months after treatment.
Results All patients were followed for at least 6 months. No related complications occurred in all patients. AOFAS score were increased from(68.3±3.6) before treatment to (83.7±3.2) and (90.8±2.2) at 3 and 6 months after treatment,respectively (P<0.05). VAS decreased from (5.2±1.2) before treatment to (3.2±0.8) and (1.9±1.2) at 3 and 6 months after treatment (P<0.05). The injury volume of cartilage and subchondral bone decreased from (71.0±42.5) mm3 before treatment to (50.6±31.5) mm3 and (36.5±27.3) mm3 at 3 and 6 months after treatment (P<0.05). The bone marrow edema volume decreased from (1 182.7±675.1) mm3 before treatment to (656.1±455.1) mm3 and (382.1±485.6) mm3 at 3 and 6 months after treatment (P<0.05).
Conclusion PRP intraarticular injection combined with ESWT for the treatment of typeⅡa OLT could alleviate clinical symptoms,effectively improve joint function,and promote cartilage repair and bone marrow edema absorption. |
| KEY WORDS Talus Osteochondral injury Megnetic resonance imaging Bone marrow edema |
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| 引用本文，请按以下格式著录参考文献： |
| 中文格式: | 刘英,刘太,付婷婷,陈君蓉,李旭雪.富血小板血浆关节腔注射联合冲击波治疗距骨骨软骨损伤的疗效观察[J].中国骨伤,2024,37(12):1224~1228 |
| 英文格式: | LIU Ying,LIU Tai,FU Ting-ting,CHEN Jun-rong,LI Xu-xue.Therapeutic effect of joint injection of platelet-rich plasma combined with shock wave on osteochondral injury of talus[J].zhongguo gu shang / China J Orthop Trauma ,2024,37(12):1224~1228 |
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