腓骨固定在胫腓骨关节外骨折中治疗效果的Meta分析
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作者Author单位AddressE-Mail
丛琳琳 CONG Lin-lin 山西医科大学基础医学院生物化学与分子生物学教研室, 山西 太原 030001
山西医科大学第二医院骨与软组织损伤修复山西省重点实验室, 山西 太原 030001
Department of Biochemistry and Molecular Biology, College of Basic Medicine, Shanxi Medical University, Taiyuan 030001, Shanxi, China
Key Laboratory of Bone and Soft Tissue Injury, Second Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi, China
 
蒋品品 JIANG Pin-pin 山西医科大学第二医院骨与软组织损伤修复山西省重点实验室, 山西 太原 030001
山西医科大学第二医院骨科, 山西 太原 030001
Key Laboratory of Bone and Soft Tissue Injury, Second Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi, China
Department of Orthopedics, the Second Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi, China
 
郭华 GUO Hua 山西医科大学第二医院骨与软组织损伤修复山西省重点实验室, 山西 太原 030001
山西医科大学第二医院骨科, 山西 太原 030001
Key Laboratory of Bone and Soft Tissue Injury, Second Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi, China
Department of Orthopedics, the Second Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi, China
 
汪航 WANG Hang 山西医科大学第二医院骨与软组织损伤修复山西省重点实验室, 山西 太原 030001
山西医科大学, 山西 太原 030001
Key Laboratory of Bone and Soft Tissue Injury, Second Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi, China
Shanxi Medical University, Taiyuan 030001, Shanxi, China
 
车先达 CHE Xian-da 山西医科大学第二医院骨与软组织损伤修复山西省重点实验室, 山西 太原 030001
山西医科大学第二医院骨科, 山西 太原 030001
Key Laboratory of Bone and Soft Tissue Injury, Second Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi, China
Department of Orthopedics, the Second Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi, China
 
王春芳 WANG Chun-fang 山西医科大学实验动物中心, 山西 太原 030001 Laboratory Animal Center, Shanxi Medical University, Taiyuan 030001, Shanxi, China  
李文晋 LI Wen-jin 山西医科大学第二临床医学院口腔科, 山西 太原 030001 Department of Stomatology, the Second Clinical School of Medicine, Shanxi Medical University, Taiyuan 030001, Shanxi, China  
李鹏翠 LI Peng-cui 山西医科大学第二医院骨与软组织损伤修复山西省重点实验室, 山西 太原 030001 Key Laboratory of Bone and Soft Tissue Injury, Second Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi, China lpc1977@163.com 
期刊信息:《中国骨伤》2024年,第37卷,第1期,第74-80页
DOI:10.12200/j.issn.1003-0034.20220290
基金项目:国家自然科学基金区域联合重点资助项目(编号:U21A20353);国家自然科学基金面上项目(编号:82172503);山西省基础研究计划自然科学研究面上项目(编号:20210302123263);山西省基础研究计划自然科学研究面上项目(编号:20210302123285)
中文摘要:

目的:通过Meta分析比较腓骨固定在胫腓骨关节外骨折中的作用及重要性。

方法:通过对中国知网、维普、万方、The Cochrane Library、Web of science、Pubmed等数据库关于固定腓骨与否对胫腓骨关节外骨折治疗疗效比较的相关文献进行检索,检索时间为2012年1月至2022年2月,使用RevMan 5.3软件进行统计分析。对腓骨固定组与不固定组的复位不良率、旋转畸形率、内翻或外翻畸形率、前或后发畸形率、不愈合率、术后感染率、二次手术率及手术时间进行比较。

结果:共纳入11篇文献,6篇随机对照研究和5篇病例对照研究,有8篇为高质量文献,共813例患者,其中腓骨固定治疗383例,未固定腓骨430例。Meta分析结果显示,与未固定腓骨相比,治疗胫腓骨关节外骨折时固定腓骨可以降低术后旋转畸形率[RR=0.22,95%CI(0.10,0.45),P<0.000 1]和内翻或外翻畸形率[RR=0.34,95%CI(0.14,0.84),P=0.02],并促进骨折愈合[RR=0.76,95%CI(0.58,0.99),P=0.04]。而复位不良率[RR=0.48,95%CI(0.10,2.33),P=0.36],前或后畸形率[RR=1.50,95%CI(0.76,2.96),P=0.24],术后感染率[RR=1.43,95%CI(0.76,2.72),P=0.27],二次手术率[RR=1.32,95%CI(0.82,2.11),P=0.25],手术时间[MD=10.21,95%CI(-17.79,38.21),P=0.47]比较差异均无统计学意义(P>0.05)。

结论:在治疗胫腓骨关节外骨折时腓骨固定组相较于不固定组在防止旋转畸形和内翻或外翻畸形以及促进愈合方面更具优势。
【关键词】胫骨  腓骨  骨折固定  Meta分析
 
Meta-analysis of the role of fibular fixation in tibiofibular fractures
ABSTRACT  

Objective To compare the role and importance of fibular fixation in tibiofibular fractures by Meta-analysis.

Methods The literature related to the comparison of the efficacy of fixation of the fibula with or without fixation on the treatment of tibiofibular fractures was searched through the databases of China Knowledge Network,Wipu,Wanfang,The Cochrane Library,Web of science and Pubmed,and statistical analysis was performed using RevMan 5.3 software. The rates of malrotation,rotational deformity,internal/external deformity,anterior/posterior deformity,non-union,infection,secondary surgery and operative time were compared between the fibula fixation and non-fixation groups.

Results A total of 11 publications were included,six randomised controlled trials and five case-control trials,eight of which were of high quality. A total of 813 cases were included,of which 383 were treated with fibula fixation and 430 with unfixed fibulae.Meta-analysis results showed that fixation of the fibulae in the treatment of tibiofibular fractures reduced the rates of postoperative rotational deformity[RR=0.22,95%CI(0.10,0.45),P<0.000 1] and internal/external deformity[RR=0.34,95%CI(0.14,0.84),P=0.02] and promoted fracture healing[RR=0.76,95%CI(0.58,0.99),P=0.04]. In contrast,the rates of poor reduction[RR=0.48,95% CI(0.10,2.33),P=0.36],anterior/posterior deformity[RR=1.50,95%CI(0.76,2.96),P=0.24],infection[RR=1.43,95%CI(0.76,2.72),P=0.27],secondary surgery[RR=1.32,95%CI(0.82,2.11),P=0.25],and operative time[MD=10.21,95%CI(-17.79,38.21),P=0.47] were not statistically significant (P>0.05) for comparison.

Conclusion Simultaneous fixation of the tibia and fibula is clinically more effective in the treatment of tibiofibular fractures.
KEY WORDS  Tibia  Fibula  Fracture fixation  Meta-analysis
 
引用本文,请按以下格式著录参考文献:
中文格式:丛琳琳,蒋品品,郭华,汪航,车先达,王春芳,李文晋,李鹏翠.腓骨固定在胫腓骨关节外骨折中治疗效果的Meta分析[J].中国骨伤,2024,37(1):74~80
英文格式:CONG Lin-lin,JIANG Pin-pin,GUO Hua,WANG Hang,CHE Xian-da,WANG Chun-fang,LI Wen-jin,LI Peng-cui.Meta-analysis of the role of fibular fixation in tibiofibular fractures[J].zhongguo gu shang / China J Orthop Trauma ,2024,37(1):74~80
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