| 膝骨关节炎患者关节冷痛感与软骨下骨髓水肿的关联性分析 |
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投稿时间：2020-03-26
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| 作者 | Author | 单位 | Address | E-Mail |
| 邓凯文 |
DENG Kai-wen |
西南医科大学附属中医医院骨科, 四川 泸州 646000
西南医科大学中西医结合学院, 四川 泸州 646000 |
Department of Orthopaedics, the Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou 646000, Sichuan, China |
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| 刘金龙 |
LIU Jin-long |
西南医科大学附属中医医院骨科, 四川 泸州 646000
西南医科大学中西医结合学院, 四川 泸州 646000 |
Department of Orthopaedics, the Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou 646000, Sichuan, China |
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| 陈恒安 |
CHEN Heng-an |
西南医科大学附属中医医院骨科, 四川 泸州 646000
西南医科大学中西医结合学院, 四川 泸州 646000 |
Department of Orthopaedics, the Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou 646000, Sichuan, China |
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| 李华 |
LI Hua |
西南医科大学附属中医医院骨科, 四川 泸州 646000 |
Department of Orthopaedics, the Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou 646000, Sichuan, China |
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| 魏涛 |
WEI Tao |
西南医科大学附属中医医院骨科, 四川 泸州 646000
西南医科大学中西医结合学院, 四川 泸州 646000 |
Department of Orthopaedics, the Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou 646000, Sichuan, China |
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| 郝琦 |
HAO Qi |
西南医科大学附属中医医院骨科, 四川 泸州 646000 |
Department of Orthopaedics, the Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou 646000, Sichuan, China |
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| 王丽彬 |
WANG Li-bin |
西南医科大学附属中医医院骨科, 四川 泸州 646000 |
Department of Orthopaedics, the Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou 646000, Sichuan, China |
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| 徐祖健 |
XU Zu-jian |
西南医科大学附属中医医院骨科, 四川 泸州 646000 |
Department of Orthopaedics, the Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou 646000, Sichuan, China |
xuzujian@21cn.com |
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| 期刊信息：《中国骨伤》2021年，第34卷，第2期，第165-169页 |
| DOI：10.12200/j.issn.1003-0034.2021.02.014 |
| 基金项目: |
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中文摘要:
目的：探讨膝冷痛与软骨下骨髓水肿（bone marrow edema，BME）的相关性。
方法：自2018年5月至2019年8月收治92例伴有膝冷痛的膝骨关节炎（knee osteoarthritis，KOA）患者，所有患者行MRI检查，将有BME的47例患者纳入观察组，无BME的45例患者纳入对照组。观察组男6例，女41例；年龄36～87（63.2±12.3）岁。对照组男10例，女35例；年龄48～84（62.7±8.3）岁。两组患者均采用药物保守治疗。采用Kellgren-Lawrence（K-L）分级评价关节退变程度，膝冷痛评分评价膝冷痛程度，采用WORMS评分评价BME分级。分析两组膝冷痛程度差异以及膝冷痛与K-L分级、BME的关系。
结果：观察组膝冷痛评分（15.55±7.68）分高于对照组的（9.42±5.50）分（t=4.383，P<0.001）；膝冷痛程度与K-L分级之间无相关性（χ2=2.138，P=0.907）；膝冷痛程度与BME分级之间存在相关性（χ2=19.709，P<0.001），两者的Spearman相关系数为rs=0.509（P<0.001）。
结论：KOA患者的膝冷痛与K-L分级无关，与BME分级有关。有BME的KOA患者膝冷痛更加明显，BME的严重程度往往与膝冷痛程度相关，存在BME越严重则膝冷痛程度越重的趋势。 |
| 【关键词】膝骨关节炎 膝冷痛 骨髓水肿 |
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| Correlation between cold pain of knee joint and subchondral bone marrow edema in patients with knee osteoarthritis |
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ABSTRACT
Objective: To investigate relationship between cold pain of knee joint and subchondral bone marrow edema (BME).
Methods: From May 2018 to August 2019,92 patients with knee osteoarthritis(KOA) associated with cold pain of knee were admitted, all patients were underwent MRI examination. The patients were divided into observation group(47 patients with BME) and control group(45 patients without BME). In observation group,there were 6 males and 41 females aged from 36 to 87 years old with an average of(63.2±12.3) years old. In control group,there were 10 males and 35 females,aged from 48 to 84 years old with an average of (62.7±8.3) years old. All patients were treated with drugs. The degree of joint degeneration was evaluated by Kellgren-Lawrence(K-L) grading. Degree of cold pain of knee was evaluated by knee cold pain score,and degree of BME was evaluated according to WORMS. The correlation between cold pain of knee and K-L grading and BME was analyzed.
Results: Score of cold pain in observation group (15.55±7.68) was higher than that of control group (9.42±5.50),which had significant difference (t=4.383,P<0.001). There was no correlation between cold pain of knee and K-L grading(χ2=2.138,P=0.907). There was correlation between BME grading and degree of cold pain in observation group(χ2=19.709,P<0.001),and Spearman correlation coefficient was rs=0.509(P<0.001).
Conclusion: The cold pain of KOA patients is not related to K-L grading,but corelate with BME grading. The Cold pain of knee was more pronounced in KOA patients with BME,and the severity of BME is often related to degree of cold pain. It seemed to be a tendency:the more serious BME,the heavier cold pain. |
| KEY WORDS Osteoarthritis,knee Cold pain of knee Bone marrow edema |
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| 引用本文，请按以下格式著录参考文献： |
| 中文格式: | 邓凯文,刘金龙,陈恒安,李华,魏涛,郝琦,王丽彬,徐祖健.膝骨关节炎患者关节冷痛感与软骨下骨髓水肿的关联性分析[J].中国骨伤,2021,34(2):165~169 |
| 英文格式: | DENG Kai-wen,LIU Jin-long,CHEN Heng-an,LI Hua,WEI Tao,HAO Qi,WANG Li-bin,XU Zu-jian.Correlation between cold pain of knee joint and subchondral bone marrow edema in patients with knee osteoarthritis[J].zhongguo gu shang / China J Orthop Trauma ,2021,34(2):165~169 |
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