Ⅰ期后路病灶清除联合腰髂间固定植骨融合术治疗腰骶椎结核
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作者Author单位AddressE-Mail
刘飞 LIU Fei 浙江省中西医结合医院骨科, 浙江 杭州 310003 Department of Orthopaedics, Hospital of Integrated Traditional Chinese and Western Medicine of Zhejiang Province, Hangzhou 310003, Zhejiang, China Callus1017@live.cn 
石仕元 SHI Shi-yuan 浙江省中西医结合医院骨科, 浙江 杭州 310003 Department of Orthopaedics, Hospital of Integrated Traditional Chinese and Western Medicine of Zhejiang Province, Hangzhou 310003, Zhejiang, China  
郑琦 ZHENG Qi 浙江省中西医结合医院骨科, 浙江 杭州 310003 Department of Orthopaedics, Hospital of Integrated Traditional Chinese and Western Medicine of Zhejiang Province, Hangzhou 310003, Zhejiang, China  
沈健 SHEN Jian 浙江省中西医结合医院骨科, 浙江 杭州 310003 Department of Orthopaedics, Hospital of Integrated Traditional Chinese and Western Medicine of Zhejiang Province, Hangzhou 310003, Zhejiang, China  
汪翼凡 WANG Yi-fan 浙江省中西医结合医院骨科, 浙江 杭州 310003 Department of Orthopaedics, Hospital of Integrated Traditional Chinese and Western Medicine of Zhejiang Province, Hangzhou 310003, Zhejiang, China  
曹天一 CAO Tian-yi 浙江省中西医结合医院骨科, 浙江 杭州 310003 Department of Orthopaedics, Hospital of Integrated Traditional Chinese and Western Medicine of Zhejiang Province, Hangzhou 310003, Zhejiang, China  
期刊信息:《中国骨伤》2020年,第33卷,第2期,第166-172页
DOI:10.12200/j.issn.1003-0034.2020.02.015
基金项目:浙江省医药卫生科技计划项目(编号:2018KY599)
中文摘要:

目的:探讨Ⅰ期后路病灶清除联合腰髂间固定植骨融合术治疗腰骶椎结核的临床疗效。

方法:回顾性分析2013年1月至2018年2月收治的31例腰骶椎结核患者,均采用Ⅰ期后路病灶清除联合腰髂间固定植骨融合手术治疗。病变范围为L4-S2,其中男18例,女13例,年龄18~77(45.9±9.1)岁。采用美国脊柱损伤协会脊髓损伤神经功能分级(ASIA分级):B级2例,C级17例,D级12例。分析手术前后血红细胞沉降率(ESR)、C-反应蛋白(CRP)、疼痛视觉模拟评分(VAS)、ASIA分级、腰骶角及椎间隙高度变化情况,并观察手术并发症、内植物稳定性和植骨融合情况。

结果:31例患者均获随访,时间为10~24(16.0±3.1)个月。1例患者术后出现局部感染、皮下积液,经换药治愈。余30例患者均Ⅰ期愈合,无窦道形成及结核复发。所有患者获治愈,未见内固定松动、断裂;植骨融合均成功,平均融合时间(4.7±1.1)个月。末次随访时患者ESR、CRP均正常,VAS评分为(1.92±0.57)分,低于术前的(6.13±1.21)分;ASIA分级C级2例,D级6例,E级23例。末次随访时腰骶角为(27.21±3.12)°,较术前的(21.42±3.75)°增大;椎间隙高度为(9.80±0.38)mm,高于术前的(7.84±0.41)mm。

结论:Ⅰ期后路病灶清除联合腰髂间固定植骨融合术治疗腰骶椎结核是一种切实可行、安全有效的方法,可在临床中推荐应用。
【关键词】后路内固定  腰髂固定  脊柱结核  腰骶段  脊柱融合术
 
One-stage posterior debridement combined with lumbar-ilium fixation and bone graft fusion for the treatment of lumbosacral tuberculosis
ABSTRACT  

Objective: To investigate the clinical effect of One-stage posterior debridement combined with lumbar-ilium fixation and bone graft fusion for the treatment of lumbosacral tuberculosis.

Methods: The clinical data of 31 patients with lumbosacral tuberculosis treated by one-stage posterior debridement combined with lumbar-ilium fixation and bone graft fusion from January 2013 to February 2018 were retrospectively analyzed. There were 18 males and 13 females,aged from 18 to 77 years old with an average of(45.9±9.1) years. The lesion segment was form L4 to S2. The preoperative ASIA grading showed that 2 cases were grade B,17 cases were grade C,12 were grade D. Pre-and post-operative C reactive protein(CRP),visual analogue scale(VAS),erythrocyte sedimentation rate(ESR),ASIA grade,lumbosacral angle and intervertebral space height were analyzed,the surgery complications,stability of internal fixation,bone fusion were observed.

Results: All the 31 patients were followed up for 10 to 24 months with an average of (16.0±3.1) months. One patient with local infection and subcutaneous hydrops was cured by dressing change. Other 30 cases got primary healing without sinus formation and no recurrence of spinal tuberculosis. All the patients were cured,no internal fixation loosening and breakage were found. All bone fusion was successful with an average fusion time of(4.7±1.1) months. At the final follow-up,ESR and CRP were normal,the VAS was decreased from(6.13±1.21) points preoperatively to(1.92±0.57) pioints,the ASIA grading showed that 2 cases were grade C,6 cases were grade D,and 23 cases were grade E. The lumbosacral angle and intervertebral space height was increased from preoperative (21.42±3.75)°,(7.84±0.41) mm to (27.21±3.12)°,(9.80±0.38) mm at the final follow-up,respectively.

Conclusion: One-stage posterior debridement combined with lumbar-ilium fixation and bone graft fusion is a practicable,effective and safe method for the treatment of lumbosacral tuberculosis. It can be recommended in clinical application.
KEY WORDS  Posterior internal fixation  Lumbo-iliac fixation  Spinal tuberculosis  Lumbosacral region  Spinal fusion
 
引用本文,请按以下格式著录参考文献:
中文格式:刘飞,石仕元,郑琦,沈健,汪翼凡,曹天一.Ⅰ期后路病灶清除联合腰髂间固定植骨融合术治疗腰骶椎结核[J].中国骨伤,2020,33(2):166~172
英文格式:LIU Fei,SHI Shi-yuan,ZHENG Qi,SHEN Jian,WANG Yi-fan,CAO Tian-yi.One-stage posterior debridement combined with lumbar-ilium fixation and bone graft fusion for the treatment of lumbosacral tuberculosis[J].zhongguo gu shang / China J Orthop Trauma ,2020,33(2):166~172
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