| 弹性髓内针与自体骨髓血注射治疗儿童骨囊肿的疗效对比研究 |
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投稿时间：2019-10-07
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| 作者 | Author | 单位 | Address | E-Mail |
| 张科学 |
ZHANG Ke-xue |
中国人民解放军总医院小儿外科, 北京 100853 |
Department of Orthopaedics, General Hospital of Chinese PLA, Beijing 100853, China |
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| 丑小冰 |
CHOU Xiao-bing |
中国人民解放军总医院小儿外科, 北京 100853 |
Department of Orthopaedics, General Hospital of Chinese PLA, Beijing 100853, China |
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| 李浩宇 |
LI Hao-yu |
中国人民解放军总医院小儿外科, 北京 100853 |
Department of Orthopaedics, General Hospital of Chinese PLA, Beijing 100853, China |
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| 陈继营 |
CHEN Ji-ying |
中国人民解放军总医院骨科, 北京 100853 |
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| 柴伟 |
CHAI Wei |
中国人民解放军总医院骨科, 北京 100853 |
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15110245907@163.com |
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| 期刊信息：《中国骨伤》2019年，第32卷，第12期，第1112-1116页 |
| DOI：10.3969/j.issn.1003-0034.2019.12.009 |
| 基金项目: |
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中文摘要:
目的：对比自体骨髓血注射与弹性髓内针支撑引流治疗儿童骨囊肿的临床疗效。
方法：自2012年1月至2016年12月将收治的单纯性骨囊肿患儿56例分为2组，自体骨髓血注射组和弹性髓内针组。其中自体骨髓血注射组28例，男16例，女12例；年龄（7.7±1.9）岁；肱骨近端10例，股骨近端8例，胫骨近端6例，股骨干4例；采用多次自体骨髓血注射治疗。弹性髓内针组28例，男18例，女10例；年龄（7.5±2.2）岁；肱骨近端11例，股骨近端7例，胫骨近端5例，股骨干4例，股骨远端1例；采用弹性髓内针支撑引流治疗。术后采用Capanna骨囊肿评价标准评价治疗效果。
结果：56例患儿均获得随访，其中弹性髓内针组随访时间17~35（25.6±4.2）个月，自体骨髓血注射组19~35（27.4±4.8）个月。按照Capanna的骨囊肿评价标准，弹性髓内针组27例治疗有效（25例治愈，2例愈合但残留部分病灶），1例复发，0例治疗无反应；自体骨髓血注射组中18例治疗有效（13例治愈，5例愈合但残留部分病灶），8例复发，2例治疗无反应；两组比较差异有统计学意义（P<0.01）。通过对两组患儿中完全治愈病例，弹性髓内针组（25例）和自体骨髓血注射组（13例）随访计算整体治愈时间，弹性髓内针组患儿治愈时间（20.2±3.5）个月，自体骨髓血注射组治愈时间（27.7±4.9）个月，差异有统计学意义（P<0.05）。
结论：对于儿童骨囊肿的治疗，弹性髓内针治疗疗效优于自体骨髓血注射，并且治愈时间更短。 |
| 【关键词】儿童 骨囊肿 注射 骨髓 |
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| Comparison of the efficacy between elastic intramedullary injection and autologous bone marrow blood injection in the treatment of bone cyst in children |
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ABSTRACT
Objective: To evaluate the efficacy of autogenous bone marrow injection and elastic intramedullary injection in the treatment of bone cyst in children.
Methods: From January 2012 to December 2016,56 children with simple bone cyst were divided into two groups:autogenous bone marrow blood injection group and elastic intramedullary needle group. There were 28 cases in the autogenous bone marrow blood injection group,16 boys and 12 girls,aged (7.7±1.9) years old,10 cases of proximal humerus,8 cases of proximal femur,6 cases of proximal tibia and 4 cases of femoral shaft. In the elastic intramedullary needle group,there were 28 cases,18 boys and 10 girls,aged(7.5±2.2) years old,11 cases of proximal humerus,7 cases of proximal femur,5 cases of proximal tibia,4 cases of femoral shaft and 1 case of distal femur. The treatment effect was evaluated by Capanna standard.
Results: All the patients were followed up,including 17 to 35(25.6±4.2) months in the elastic intramedullary needle group and 19 to 35(27.4±4.8) months in the autogenous marrow blood injection group. According to Capanna's evaluation standard of bone cyst,27 patients in the elastic intramedullary needle group were treated effectively(25 patients cured,2 patients healed but some remained lesions),1 patients recurred,0 patient had no response to treatment; 18 patients in the autogenous bone marrow blood injection group were treated effectively(13 patients cured,5 patients healed but some remained lesions),8 patients of cyst recurred,2 patients had no response to treatment;the difference between the two groups was statistically significant(P<0.01). The overall cure time was calculated by the follow-up of 25 cases in the elastic intramedullary injection group and 13 cases in the autogenous marrow blood injection group. The cure time was(20.2±3.5) months in the elastic intramedullary injection group and(27.7±4.9) months in the autogenous marrow blood injection group. The difference was statistically significant(P<0.05).
Conclusion: For the treatment of bone cyst in children,the therapeutic effect of elastic intramedullary needle is better than that of autogenous bone marrow blood injection,and the cure time is shorter. |
| KEY WORDS Child Bone cysts Injections Bone marrow |
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| 引用本文，请按以下格式著录参考文献： |
| 中文格式: | 张科学,丑小冰,李浩宇,陈继营,柴伟.弹性髓内针与自体骨髓血注射治疗儿童骨囊肿的疗效对比研究[J].中国骨伤,2019,32(12):1112~1116 |
| 英文格式: | ZHANG Ke-xue,CHOU Xiao-bing,LI Hao-yu,CHEN Ji-ying,CHAI Wei.Comparison of the efficacy between elastic intramedullary injection and autologous bone marrow blood injection in the treatment of bone cyst in children[J].zhongguo gu shang / China J Orthop Trauma ,2019,32(12):1112~1116 |
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