3D打印多孔钛钢板一体化植入体修复髋臼后壁粉碎性骨折合并骨缺损的初步研究
摘要点击次数: 1963   全文下载次数: 1100   投稿时间:2018-07-20    
作者Author单位AddressE-Mail
张彦超 ZHANG Yan-chao 中国医科大学附属盛京医院创伤骨科, 辽宁 沈阳 110004 Department of Orthopaedics, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning, China  
李建军 LI Jian-jun 中国医科大学附属盛京医院创伤骨科, 辽宁 沈阳 110004 Department of Orthopaedics, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning, China lij2046@126.com 
侯文韬 HOU Wen-tao 中国科学院金属研究所材料科学国家实验室, 辽宁 沈阳 110016  
张海峰 ZHANG Hai-feng 东北大学中荷生物医学与信息工程学院, 辽宁 沈阳 110004  
刘纪红 LIU Ji-hong 东北大学中荷生物医学与信息工程学院, 辽宁 沈阳 110004  
期刊信息:《中国骨伤》2019年,第32卷,第5期,第469-474页
DOI:10.3969/j.issn.1003-0034.2019.05.016
基金项目:辽宁省自然科学基金项目(编号:201602836)
中文摘要:

目的:探讨应用计算机辅助设计(computer-aided design,CAD)结合3D打印技术对髋臼后壁粉碎性骨折合并骨软骨缺损进行修复重建的可行性,评估多孔钛合金支架钢板一体化植入体复合氮化钛生物陶瓷涂层的生物力学性能。

方法:基于连续断层CT图像,利用CAD软件来构建具有特定三维内部结构的多孔钛钢板一体化植入体数字模型,以Ti6Al4V粉末为原材料打印出实体并于其关节面复合氮化钛涂层,观察植入体与髋臼匹配和贴附情况;利用Ansys软件进行有限元建模,分析正常组、传统组及植入体组髋臼在相同载荷状态下的应力分布、应力传导及形变位移等情况,验证植入体的生物力学性能。

结果:植入体的多孔钛合金支架与髋臼匹配程度良好,钢板形态基本与骨表面贴附,根据Matta复位标准评定为优。有限元分析结果显示:植入体重建后髋臼在Von Mises应力峰值13.38 MPa接近正常组13.11 MPa,小于传统组15.66 MPa;植入体重建后的髋臼在应力分布和传导与正常组基本一致,稍优于传统组;植入体的最大相对位移为0.166 mm,处于可以接受的范围。

结论:3D技术制备的多孔钛合金支架钢板一体化植入体复合氮化钛涂层具备优良的匹配度和生物力学性能;解剖重建使后壁头臼应力分布及传导恢复比较理想,接近正常的髋关节,其为临床治疗髋臼后壁粉碎性骨折合并严重骨缺损的病例提供新选择。
【关键词】打印,三维  有限元分析  髋臼  骨折,粉碎性
 
A preliminary study of three-dimensional printed porous titanium plate integrated implant for the repair of comminuted acetabular posterior wall fracture with bone defect
ABSTRACT  

Objective:To explore the feasibility of using computer-aided design(CAD) combined with 3D printing technology to repair and reconstruct the comminuted fracture of the posterior wall of acetabulum with osteochondral defect,to evaluate the biomechanical properties of composite titanium nitride bioceramic coatings with porous titanium alloy scaffolds and steel plate integrated implants.

Methods:Based on CT images of continuous tomography,the computer-aided design software was used to construct a digital model of porous titanium alloy plate implant with a specially open cellular three-dimensional structure,and the three-dimensional implant was prepared with Ti6Vl4V powder by using the 3D printing technology,following by titanium nitride coating on its articular surface. The degree of matching and attachment between the implant and acetabulum were observed;Ansys software was used for finite element modeling to analyze the stress distribution,stress conduction and deformation displacement of the acetabulum of the normal group,the traditional group and the implant group under the same load state,and to verify the biomechanical properties of the implant.

Results:The porous titanium alloy implant fit well with the acetabular bone defects,the shape of the plate was well attached to the bone surface,and it was rated as excellent according to the Matta criteria. The Von Mises stress peak of the implant group 13.38 MPa was close to the normal group 13.11 MPa and smaller than that in the traditional group 15.66 MPa. The Von Mises stress distribution and conduction of implant group were basically consistent with the normal group,slightly better than the traditional group;the maximum relative displacement of the implant was 0.166 mm,according to the finite element analysis.

Conclusion:The porous titanium alloy stent plate implant with titanium nitride coating prepared by 3D technology has excellent matching degree and biomechanical properties;the anatomical reconstruction makes the stress distribution and conduction recovery well,close to normal hip joints,which provides a new option for the clinical treatment of comminuted posterior acetabular wall fractures with severe bone defects.
KEY WORDS  Printing,three-dimensional  Finite element analysis  Acetabulum  Fractures,comminuted
 
引用本文,请按以下格式著录参考文献:
中文格式:张彦超,李建军,侯文韬,张海峰,刘纪红.3D打印多孔钛钢板一体化植入体修复髋臼后壁粉碎性骨折合并骨缺损的初步研究[J].中国骨伤,2019,32(5):469~474
英文格式:ZHANG Yan-chao,LI Jian-jun,HOU Wen-tao,ZHANG Hai-feng,LIU Ji-hong.A preliminary study of three-dimensional printed porous titanium plate integrated implant for the repair of comminuted acetabular posterior wall fracture with bone defect[J].zhongguo gu shang / China J Orthop Trauma ,2019,32(5):469~474
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