退行性腰椎侧凸与骨质疏松症的相关性分析
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作者Author单位AddressE-Mail
黄道余 HUANG Dao-yu 南京医科大学第二附属医院骨科, 江苏 南京 210000 Department of Orthopaedics, the Second Affiliated Hospital of Nanjing Medical University, Nanjing 210000, Jiangsu, China  
沈亚骏 SHEN Ya-jun 南京医科大学第二附属医院骨科, 江苏 南京 210000 Department of Orthopaedics, the Second Affiliated Hospital of Nanjing Medical University, Nanjing 210000, Jiangsu, China  
王飞 WANG Fei 中国人民解放军陆军总医院骨科, 北京 100700  
李放 LI Fang 中国人民解放军陆军总医院骨科, 北京 100700  
房照 FANG Zhao 中国人民解放军陆军总医院骨科, 北京 100700  
刘军 LIU Jun 南京医科大学第二附属医院骨科, 江苏 南京 210000 Department of Orthopaedics, the Second Affiliated Hospital of Nanjing Medical University, Nanjing 210000, Jiangsu, China 13776698080@139.com 
期刊信息:《中国骨伤》2019年,第32卷,第3期,第244-247页
DOI:10.3969/j.issn.1003-0034.2019.03.010
基金项目:
中文摘要:

目的:研究成年人腰椎退变性侧凸与骨质疏松的相互关系。

方法:自2012年3月至2016年6月,采用回顾性分析方法对53例腰椎退变性侧凸患者进行腰椎退变性侧凸与骨质疏松症相关性研究,男11例,女42例,年龄63~76岁,平均69岁,匹配同期就诊的非腰椎侧凸患者53例,其中腰椎间盘突出症33例,腰椎管狭窄症13例,腰椎滑脱症7例,男16例,女37例,年龄59~74岁,平均68.5岁。53例患者均拍摄腰椎正侧位X线片及腰椎MRI确诊,测量并记录腰椎侧凸Cobb角。运用双能X射线吸收法对所有患者进行骨密度检查,记录腰椎(L2-L4)、股骨颈、股骨粗隆、Ward三角部位T值。采用Linear regression研究腰椎侧凸角度与骨质疏松的相关性。

结果:腰椎侧凸组与非腰椎侧凸组两者骨密度T值差异有统计学意义,腰椎退变性侧凸患者骨密度T值(-2.56±0.65)明显高于非腰椎侧凸组(-1.39±0.77)(P<0.05),腰椎侧凸患者腰椎(L2-L4)、股骨颈、股骨粗隆、Ward三角部位的T值与侧凸Cobb角无明显相关性。

结论:骨质疏松是发生腰椎退变性侧凸的危险因素,但侧凸程度与骨质疏松程度无明显相关性。
【关键词】骨质疏松症  退行性腰椎侧凸  骨密度
 
Correlative analysis of degenerative lumbar scoliosis and osteoporosis
ABSTRACT  

Objective:To investigate the correlation between degenerative lumbar scoliosis and osteoporosis in adults.

MethodsFrom March 2012 to June 2016,the clinical data of 53 patients with degenerative lumbar scoliosis were retrospectively analyzed for a correlation study between degenerative lumbar scoliosis and osteoporosis. Fifty-three patients with degenerative lumbar scoliosis were selected as observation group and another 53 inpatients without lumbar scoliosis as control group. There were 11 males and 42 females with an average age of 69 years (range 63 to 76 years) old in observation group. And in control group,there were 16 males and 37 females with an average age of 68.5 years (range 59 to 74 years) old,including lumbar disc herniation in 33 cases,lumbar spinal stenosis in 13 cases,spondylolisthesis in 7 cases. The 53 patients with degenerative lumbar scoliosis were confirmed by X-ray and MRI,their Cobb angle of lumbar scoliosis was measured. Dual energy X-ray absorptiometry was used to measure the bone mineral density,the T values of L2-L4 segments,femoral neck,Ward triangle and femoral trochanter were recorded. Linear regression analysis was used to analyze the correlation between osteoporosis and degenerative lumbar scoliosis.

ResultsThere were significant differences in the bone mineral density T values between two groups (P<0.05). Bone mineral density T value in patients with lumbar scoliosis were significantly higher than that in the patients with no lumbar scoliosis (P<0.05),(-2.56±0.65 vs -1.39±0.77). The T values of L2-L4 segments,femoral neck,Ward triangle and femoral trochanter had no remarkable correlation with Cobb's angles.

ConclusionOsteoporosis is a risk factor for degenerative scoliosis,but the severity of osteoporosis and degree of scoliosis has no obvious correlation.
KEY WORDS  Osteoporosis  Degenerative lumbar scoliosis  Bone mineral density
 
引用本文,请按以下格式著录参考文献:
中文格式:黄道余,沈亚骏,王飞,李放,房照,刘军.退行性腰椎侧凸与骨质疏松症的相关性分析[J].中国骨伤,2019,32(3):244~247
英文格式:HUANG Dao-yu,SHEN Ya-jun,WANG Fei,LI Fang,FANG Zhao,LIU Jun.Correlative analysis of degenerative lumbar scoliosis and osteoporosis[J].zhongguo gu shang / China J Orthop Trauma ,2019,32(3):244~247
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