CT引导下微创手术治疗腰骶椎结核的中远期临床观察
摘要点击次数: 1911   全文下载次数: 1112   投稿时间:2015-05-25    
作者Author单位AddressE-Mail
张琳 ZHANG Lin 解放军总医院海南分院, 海南 三亚 572000 The General Hospital of China People's Liberation Army, Beijing 100853, China  
张西峰 ZHANG Xi-feng 中国人民解放军总医院, 北京 100853 656780949@qq.com 
侯克东 HOU Ke-dong 北京市平谷区医院, 北京 101200  
杨华东 YANG Hua-dong 中国人民解放军总医院, 北京 100853  
蒋续钢 JIANG Xu-gang 山西医科大学第二临床医学院, 山西 太原 030000  
李凝道 LI Ning-dao 山西医科大学第二临床医学院, 山西 太原 030000  
期刊信息:《中国骨伤》2016年,第29卷,第3期,第270-274页
DOI:10.3969/j.issn.1003-0034.2016.03.015
基金项目:
中文摘要:目的:探讨CT引导下微创手术治疗腰骶椎结核的临床疗效。方法:对2002年1月至2013年3月收治的保守治疗无效的145例腰骶椎结核患者的临床资料进行回顾性分析,男84例,女61例;其中143例获得随访,年龄2.5~81岁,平均(42.60±17.14)岁。术后复发患者14例(6例有内固定,8例无内固定);椎旁脓肿的患者32例。术前合并左下肢无力浅感觉差1例,肌力减退1例,此2例患者Frankel分级均为D级,其他患者为E级。144例实施CT引导下在病灶和脓肿内置管局部化疗灌注冲洗,1例行小开窗手术结合局部化疗治疗。观察患者治疗前及末次随访时的血沉及腰椎前凸角度(lumbar lordosis,LL).结果:143例患者获随访,时间为21~149个月,平均67个月,其中73例获得5年以上随访。所有患者达临床愈合。术前血沉(44.96±12.41) mm/h,末次随访时(7.25±3.43) mm/h,两者差异有统计学意义(t=35.06,P=0.000).治疗前腰椎前凸角为(36.32±8.55)°,末次随访时为(33.35±8.16)°,两者差异有统计学意义(t=13.90,P=0.000).结论:经保守治疗3个月以上无效,脊柱稳定性较好且神经症状的程度在Frankel分级D级以上的患者,行微创治疗辅以全身抗结核药物化学治疗效果较好。
【关键词】结核,脊柱  外科手术,微创性  抗结核药  局部化疗
 
Long-term clinical studies on the treatment of lumbosacral spinal tuberculosis with CT-guided minimally invasive surgery
ABSTRACT  Objective:To evaluate the clinical effects of CT-guided percutaneous puncture and local chemotherapy for lumbosacral spinal tuberculosis. Methods:From January 2002 to March 2013, 145 patients (84 males and 61 females) with lumbosacral spinal tuberculosis underwent failed conservative treatment were treated with CT-guided minimally invasive surgery. Their clinical data were retrospectively analyzed. Among them, 143 patients were followed up, aged from 2.5 to 81 years with an average of (42.60±17.14) years. Fourteen cases (6 cases with internal fixation and 8 cases without internal fixation) recurred and 32 cases complicated with paraspinal abscess after operation. Preoperatively 1 case complicated with lower limb weakness and superficial sensation worse, 1 case with muscle strength decrease, this 2 cases were grade D of Frankle, other cases were grade E. And 1 patient underwent fenestration operation and local chemotherapy, 144 cases with CT-guided percutaneous puncture and local chemotherapy. ESR and lumbar lordosis angle of all patients were observed preoperatively and final follow-up. Results:The mean follow-up time was 67 months (ranged, 21 to 149 months) in 143 cases, and 73 cases more than 5 years. All patients obtained clinical healing. ESR was (44.96±12.41) mm/h before operation and (7.25±3.43) mm/h at final follow-up, there was significant difference between preoperative and postoperative(t=35.06, P=0.000). Lumbar lordosis angle was(36.32±8.55)° before operation and(33.35±8.16)° at final follow-up, there was significant difference between preoperative and postoperative(t=13.90, P=0.000). Conclusion:When conservative treatment fails for 3 months or more, the patients have good spinal stabilization, nerve function is more than grade D of Frankel, CT-guided percutaneous puncture and local chemotherapy can get satisfactory outcomes for lumbosacral spinal tuberculosis.
KEY WORDS  Tuberculosis,spinal  Surgical procedures,minimally invasive  Antitubercular agents  Local chemotherapy
 
引用本文,请按以下格式著录参考文献:
中文格式:张琳,张西峰,侯克东,杨华东,蒋续钢,李凝道.CT引导下微创手术治疗腰骶椎结核的中远期临床观察[J].中国骨伤,2016,29(3):270~274
英文格式:ZHANG Lin,ZHANG Xi-feng,HOU Ke-dong,YANG Hua-dong,JIANG Xu-gang,LI Ning-dao.Long-term clinical studies on the treatment of lumbosacral spinal tuberculosis with CT-guided minimally invasive surgery[J].zhongguo gu shang / China J Orthop Trauma ,2016,29(3):270~274
阅读全文  下载  查看/发表评论  下载PDF阅读器
关闭




版权所有:《中国骨伤》杂志社京ICP备12048066号-2  版权声明
地址:北京市东直门内南小街甲16号,100700
电话:010-64089487 传真:010-64089792 Email:zggszz@sina.com

京公网安备 11010102004237号