| 脊柱转移瘤脊髓压迫症的治疗进展 |
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投稿时间：2014-09-20
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| 作者 | Author | 单位 | Address | E-Mail |
| 刘耀升 |
LIU Yao-sheng |
解放军第307医院骨科, 北京 100071 |
Department of Orthopaedics, the 307 Hospital of PLA, Beijing 100071, China |
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| 何其臻 |
HE Qi-zhen |
解放军第307医院骨科, 北京 100071 |
Department of Orthopaedics, the 307 Hospital of PLA, Beijing 100071, China |
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| 刘蜀彬 |
LIU Shu-bin |
解放军第307医院骨科, 北京 100071 |
Department of Orthopaedics, the 307 Hospital of PLA, Beijing 100071, China |
15810069346@qq.com |
| 蒋伟刚 |
JIANG Wei-gang |
解放军第307医院骨科, 北京 100071 |
Department of Orthopaedics, the 307 Hospital of PLA, Beijing 100071, China |
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| 雷明星 |
LEI Ming-xing |
解放军第307医院骨科, 北京 100071 |
Department of Orthopaedics, the 307 Hospital of PLA, Beijing 100071, China |
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| 期刊信息：《中国骨伤》2016年，第29卷，第1期，第94-98页 |
| DOI：10.3969/j.issn.1003-0034.2016.01.022 |
| 基金项目:北京市科委首都临床特色课题(编号:z131107002213052) |
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| 中文摘要:癌症患者脊柱转移是造成脊髓硬膜外压迫的重要病源。随着肿瘤治疗技术的改善,脊柱转移瘤患者生存期提高,转移性脊髓硬膜外压迫的发病率也随之增加。转移性硬膜外脊髓压迫当伴有脊柱不稳定时,可通过手术方式对脊髓周围进行减压,同时进行脊柱稳定性的重建。若肿瘤对放射线敏感而没有合并脊柱不稳定时,放疗是有效的治疗方式。目前,脊柱立体定向放疗、经皮微创技术如椎体成形术和后凸成形术、 经皮椎弓根内固定术、射频消融术对于某些适合的脊柱转移瘤都已取的理想的治疗效果。 |
| 【关键词】脊柱 肿瘤转移 脊髓压迫症 分子靶向治疗 立体定向放疗 外科手术 综述文献 |
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| Therapy progress of spinal cord compression by metastatic spinal tumor |
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| ABSTRACT Metastatic epidural compression of the spinal cord is a significant source of morbidity in patients with systemic cancer. With improvment of oncotheray,survival period in the patients is improving and metastatic cord compression is encountered increasingly often. Surgical management performed for early circumferential decompression for the spinal cord compression with spine instability,and spine reconstruction performed. Patients with radiosensitive tumours without spine instability,radiotherapy is an effective therapy. Spinal stereotactic radiosurgery and minimally invasive techniques,such as vertebroplasty and kyphoplasty,percutaneous pedicle screw fixation,radiofrequency ablation are promising options for treatment of certain selected patients with spinal metastases. |
| KEY WORDS Spine Neoplasm metastasis Spinal cord compression Molecular targeted therapy Stereotactic radiotherapy Surgical procedures,operative Review literature |
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| 引用本文，请按以下格式著录参考文献： |
| 中文格式: | 刘耀升,何其臻,刘蜀彬,蒋伟刚,雷明星.脊柱转移瘤脊髓压迫症的治疗进展[J].中国骨伤,2016,29(1):94~98 |
| 英文格式: | LIU Yao-sheng,HE Qi-zhen,LIU Shu-bin,JIANG Wei-gang,LEI Ming-xing.Therapy progress of spinal cord compression by metastatic spinal tumor[J].zhongguo gu shang / China J Orthop Trauma ,2016,29(1):94~98 |
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