| 骨质疏松性骨折风险的FRAX评分与脊柱形态的相关性研究 |
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投稿时间：2012-02-05
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| 作者 | Author | 单位 | Address | E-Mail |
| 蒋雪生 |
JIANG Xue-sheng |
湖州市中心医院骨科, 浙江 湖州 313000 |
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| 李建有 |
LI Jian-you |
湖州市中心医院骨科, 浙江 湖州 313000 |
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| 张文均 |
ZHANG Wen-jun |
深圳市平乐骨伤科医院骨科, 广东 深圳 508010 |
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| 王华军 |
WANG Hua-jun |
石家庄市骨科医院骨科, 河北 石家庄 050011 |
Divison of Surgery, College of Traditional Chinese Medicine, South Medical University, Guangzhou 510515, Guangdong, China |
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| 陈庭瑞 |
CHEN Ting-rui |
南方医科大学中医 药学院外科教研室, 广东 广州 510515 |
Divison of Surgery, College of Traditional Chinese Medicine, South Medical University, Guangzhou 510515, Guangdong, China |
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| 蓝文锐 |
LAN Wen-rui |
南方医科大学中医 药学院外科教研室, 广东 广州 510515 |
Divison of Surgery, College of Traditional Chinese Medicine, South Medical University, Guangzhou 510515, Guangdong, China |
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| 李义凯 |
LI Yi-kai |
南方医科大学中医 药学院外科教研室, 广东 广州 510515 |
Divison of Surgery, College of Traditional Chinese Medicine, South Medical University, Guangzhou 510515, Guangdong, China |
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| 陈超 |
CHEN Chao |
南方医科大学中医 药学院外科教研室, 广东 广州 510515 |
Divison of Surgery, College of Traditional Chinese Medicine, South Medical University, Guangzhou 510515, Guangdong, China |
chenchao@smu.edu.cn |
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| 期刊信息：《中国骨伤》2013年，第26卷，第9期，第730-734页 |
| DOI：10.3969/j.issn.1003-0034.2013.09.007 |
| 基金项目:国家自然科学基金(编号:30700893) |
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中文摘要:
目的：探讨骨质疏松老年人脊柱形态与全身骨折风险之间的关系.
方法：2010年6月至2011年1月,应用双能X线(DEXA)测量107位老年人股骨颈及腰椎骨密度(BMD),其中男41例,女66例;年龄48～82岁,平均(67±6)岁.并对其进行骨折风险因素问卷调查,联合应用世界卫生组织(WHO)推荐的骨折风险测评工具(FRAX)对老年人进行骨质疏松性骨折风险评估,计算出每个人10年内髋部骨折概率和10年内主要的骨质疏松性骨折(脊柱、髋部、前臂或肩部骨折)概率.采用Spinal mouse测量老年人站立位的脊柱椎间夹角、脊柱曲度,并分析骨折风险概率与脊柱椎间夹角、脊柱曲度的相关性,做曲线拟合分析.
结果：骨质疏松性骨折概率与直立位的T7、T8夹角,胸椎曲度,腰椎曲度成正相关(P<0.05),与前倾角成正相关(P<0.05),与其他椎间夹角无明显相关关系.
结论：老年人的脊柱形态特征能够反映骨质疏松性骨折风险的高低. |
| 【关键词】骨折 骨质疏松 脊柱 髋 老年人 |
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| Relationship between fracture risk evaluated by FRAX tool and spinal curvature |
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ABSTRACT
Objective：To investigate the relationship between the risk of osteoporotic fracture in old people and the spinal morphology.
Methods：From June 2010 to January 2011,107 old people's BMD of femoral neck were measured by Dual energy X-ray.A questionnaire survey on fracture risk factors of the 107 aged and dat a collection were adopted.Among the aged,41 were male and 66 were female,ranging in age from 48 to 82 years old,with an averaged of (67±6) years old.The fracture risk assessment tools (FRAX) recommended by WHO were adopted.A risk assessment on osteoporotic fracture in old people was done,followed with the calculation of the probability of the hip fracture and the main bone fractures (spine,hip,forearm or shoulder fractures) in ten years.The angles of spine vertebra,spine curvature in the upright positions of the old people were measured by using Spinalmouse.The correlation analysis along with curve fitting analysis between the probability of fracture risk and included angles of spine vertebra,spine curvature were done.
Results：The probability of osteoporotic fracture had a positive relation with thoracic vertebra T7 and T8,thoracic sp ine curvature,lumbar curvature and incline angle in upright position (P<0.05).
Conclusion：The old people's morphological characteristics of spine have the ability to reflect the risk level of osteoporotic fracture. |
| KEY WORDS Fractures Osteoporosis Spine Hip Aged |
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| 引用本文，请按以下格式著录参考文献： |
| 中文格式: | 蒋雪生,李建有,张文均,王华军,陈庭瑞,蓝文锐,李义凯,陈超.骨质疏松性骨折风险的FRAX评分与脊柱形态的相关性研究[J].中国骨伤,2013,26(9):730~734 |
| 英文格式: | JIANG Xue-sheng,LI Jian-you,ZHANG Wen-jun,WANG Hua-jun,CHEN Ting-rui,LAN Wen-rui,LI Yi-kai,CHEN Chao.Relationship between fracture risk evaluated by FRAX tool and spinal curvature[J].zhongguo gu shang / China J Orthop Trauma ,2013,26(9):730~734 |
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