| 脊髓损伤的治疗现状与进展 |
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投稿时间：2009-10-22
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| 期刊信息：《中国骨伤》2010年，第23卷，第1期，第70-73页 |
| DOI：10.3969/j.issn.1003-0034.2010.01.026 |
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| 中文摘要:脊髓损伤分为原发性损伤和继发性损伤，治疗主要目的在于阻止或减少继发性损伤。传统治疗方法以手术解除脊髓压迫和(或)通过体内固定维持脊柱稳定性并配合药物、高压氧等非手术治疗来减轻脊髓继发性损伤，但对于神经保护和神经再生疗效欠佳，主要归因于损伤后脊髓中的环境不利于修复的发生和发展。近年来，细胞移植和转基因疗法治疗脊髓损伤，在动物实验中已取得了一定效果，并有初步临床尝试，具有很好的临床应用前景。 |
| 【关键词】脊髓损伤 外科手术 细胞移植 转基因 综述文献 |
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| Current situation and progression in the treatment of spinal cord injury |
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| ABSTRACT Spinal cord injuries include original injury and secondary injury. The aim of therapy is to prevent and reduce the secondary injury. The traditional therapy can alleviate the secondary injury of spinal cord through surgery that can both relieve the pressure of spinal cord and maintain the spinal stability with the internal fixation,medicine and hyperbaric oxygen therapy were applied together. But,the effect of neuroprotection and neurotization of traditional therapy is worse and the most of all is the environment in the spinal cord injury that make against the repairing. At present,the treatment of spinal cord injury with cell transplantation and gene therapy have made achievements in the animal experiment and have been simply tested in clinical. Cell transplantation and gene therapy have a great clinical utilization. |
| KEY WORDS Spinal cord injuries Surgical procedures,operative Cell transplantation Transgenes Review literature |
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| 引用本文，请按以下格式著录参考文献： |
| 中文格式: | 李盛华,郭平德,王文晶.脊髓损伤的治疗现状与进展[J].中国骨伤,2010,23(1):70~73 |
| 英文格式: | LI Sheng-hua,GUO Ping-de,WANG Wen-jing.Current situation and progression in the treatment of spinal cord injury[J].zhongguo gu shang / China J Orthop Trauma ,2010,23(1):70~73 |
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