刮除植骨治疗骨巨细胞瘤的临床研究
摘要点击次数: 2011   全文下载次数: 1460   投稿时间:2007-02-27    
作者Author单位AddressE-Mail
薛青贵 XUE Qing-gui 解放军第95医院骨科二区,福建莆田351100 Department of Orthopaedics Surgery,the 95th Hospital of PLA,Putian 351100,Fujian,China  
林国兵 LIN Guo-bing 解放军第95医院骨科二区,福建莆田351100 Department of Orthopaedics Surgery,the 95th Hospital of PLA,Putian 351100,Fujian,China  
郭文荣 GUO Wen-rong 解放军第95医院骨科二区,福建莆田351100 Department of Orthopaedics Surgery,the 95th Hospital of PLA,Putian 351100,Fujian,China  
期刊信息:《中国骨伤》2007年,第20卷,第9期,第597-598页
DOI:doi:10.3969/j.issn.1003-0034.yyyy.nn.zzz
基金项目:
中文摘要:

目的:通过刮除植骨对骨巨细胞瘤刮除后骨缺损重建的效果分析,了解自体骨或异体骨移植后局部复发率和并发症发生情况。

方法:随访手术治疗72例骨巨细胞瘤,男31例,女41例;年龄14~66岁,平均32.4岁。主要发病部位为股骨上端5例,股骨下端21例,胫骨上端17例,肱骨上端7例及桡骨远端9例。外科治疗以X线Cam-panacci分级系统或Enneking外科分期标准为原则,采用囊内刮除植骨(病灶刮除术和肿瘤瘤段切除术),对肿瘤切除,进行临床和放射学随访。

结果:72例中有53例获得随访,随访时间8~48个月,平均2年4个月。功能评价按Ennek-ing标准,本组优25例,良21例,一般5例,优良率90.19%。

结论:本研究提示骨巨细胞瘤刮除后行骨移植修复骨缺损、重建关节,手术刮除彻底,复发率低,植骨愈合可靠,重建后的关节功能良好,可能与肿瘤充分刮除有关。
【关键词】巨细胞瘤,骨  骨移植  四肢  骨科手术方法
 
Treatment of giant-cell tumor of bone with curettage and bone-grafting
ABSTRACT  

Objective: To evaluate the effects and the complications of autograft and allograft replacement in the management of giant-cell tumor.

Methods: Seventy-two patients with giant-cell tumors of extremities were treated by curettage and enbloc resection.In the study,31 patients were male and 41 patients were female,ranging in age from 14 to 66 years,with an average of 32.4 years.Five patients had the tumors in the upper end of the femoral shaft, 21 patients had the tumors in the lower end of the femoral shaft,17 patients had tumors in the upper end of the tibia,7 patients had the tumor in the upper end of the humerus,and 9 patients had the tumors in the lower end of the radius.Surgical treatments were adopted according to Campanacci radiological grade or Enneking grade.All the patients were treated with intralesional curettage by using high-speed burr and reconstructed with bone-grafting.

Results: Among 72 patients,53 patients were followed up (range,8 to 48 months),with an average of 2 years and 4 months.According to Enneking functional evaluation system,25 patients obtained an excellent result,21 good,and 5 fair,the excellent and good rate was 90.19%.

Conclusion: Repairing the defect of bone and reconstruction of the joint with bone graft after excision of tumor are a good surgical treatement,which insures faster recovery of joint function,lower of rate of local recurrent and reliable bone reunions.The recurrence is related to thorough remove of the tumor.
KEY WORDS  Giant cell tumor of bone  Bone transplantation  Extremities  Orthopaedics operative methods
 
引用本文,请按以下格式著录参考文献:
中文格式:薛青贵,林国兵,郭文荣.刮除植骨治疗骨巨细胞瘤的临床研究[J].中国骨伤,2007,20(9):597~598
英文格式:XUE Qing-gui,LIN Guo-bing,GUO Wen-rong.Treatment of giant-cell tumor of bone with curettage and bone-grafting[J].zhongguo gu shang / China J Orthop Trauma ,2007,20(9):597~598
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