| 关节镜术加益气补肾行血汤治疗膝骨性关节炎疗效观察 |
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投稿时间：2005-03-02
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| 作者 | Author | 单位 | Address | E-Mail |
| 贺宪 |
HE Xian |
暨南大学医学院,广东广州510630 |
Medical College of Jinan University,Guangzhou Guangdong,510630,China |
hexian1978@163.com |
| 高凌光 |
GAO Ling-guang |
暨南大学医学院附属第六医院骨科 |
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| 魏春山 |
WEI Chun-shan |
暨南大学医学院,广东广州510630 |
Medical College of Jinan University,Guangzhou Guangdong,510630,China |
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| 陈孝银 |
CHEN Xiao-yin |
暨南大学医学院,广东广州510630 |
Medical College of Jinan University,Guangzhou Guangdong,510630,China |
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| 王德就 |
WANG De-jiu |
暨南大学医学院,广东广州510630 |
Medical College of Jinan University,Guangzhou Guangdong,510630,China |
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| 期刊信息：《中国骨伤》2005年，第18卷，第8期，第449-451页 |
| DOI：doi:10.3969/j.issn.1003-0034.yyyy.nn.zzz |
| 基金项目:广东省中医药局管理课题(编号:1040077) |
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中文摘要:
目的:探讨关节镜手术加内服益气补肾行血汤治疗膝骨性关节炎(OA)的临床疗效和对关节液、血清中IL-1、IL-6水平的影响。
方法:将96例OA患者随机分成治疗组(47例)和对照组(49例)。治疗组采用关节镜手术配合内服益气补肾行血汤4个疗程(7d为1个疗程),对照组单纯采用关节镜手术,然后观察术后1个月的临床疗效和随访1年的复发情况,并检测术前和术后1个月血清与关节液中的IL-1I、L-6的含量。
结果:治疗组疗效优于对照组(P<0.05),两组关节液、血清中IL-1、IL-6含量水平均明显下降(P<0.01),且治疗组下降幅度优于对照组(P<0.05)。随访1年治疗组复发率7.9%,对照组复发率30.3%。
结论:中药内服配合关节镜手术治疗OA近期疗效满意,能明显改善膝关节功能。 |
| 【关键词】骨关节炎,膝 外科手术,关节镜 中药 |
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| Outcome of arthroscopic operation plus administration of qi-invigorating,kidney-supplementing,blood-activating decoction (益气补肾行血汤) on treatment of knee osteoarthritis |
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ABSTRACT
Objective: To explore the outcome of arthroscopic operation plus oral administration of qi-invigorating,kidney-supplementing,blood-activating decoction on knee osteoarthritis and influences on the level of IL-1,IL-6 in serum and synovial fluid.
Methods:Ninety-six osteoarthritis patients were randomly divided into two groups:a treatment group(47 cases)treated by arthroscopic operation plus oral administration of qi-invigorating,kidney-supplementing,blood-activating decoction for 4 weeks and a control group(49 cases) treated by simple arthroscopic operation.Clinical outcome were observed for 1 month after operation,and the relapse was observed during a period of 1-year follow up.The level of IL-1,IL-6 in serum and synovial fluid were detected respectively before operation and 1 month after operation.
Results:The clinical outcome of the treatment group was superior to that of the control group(P<0.05).The level of IL-1,IL-6 in serum and synovial fluid was greatly declined in both groups (P<0.01),and the descent range of the treatment group was superior to the control group (P<0.05).The follow-up for one year showed that the relapse rate was 7.9% in the tratment group and 30.3% in the control group.
Conclusion:Knee osteoarthritis treated with arthroscopic operation plus oral administration of qi-invigorating,kidney-supplementing,blood-activating decoction can achieve satisfactory short-time effect. |
| KEY WORDS Osteoarthritis,knee Surgical procedures,arthroscopy Chinese herbs |
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| 引用本文，请按以下格式著录参考文献： |
| 中文格式: | 贺宪,高凌光,魏春山,陈孝银,王德就.关节镜术加益气补肾行血汤治疗膝骨性关节炎疗效观察[J].中国骨伤,2005,18(8):449~451 |
| 英文格式: | HE Xian,GAO Ling-guang,WEI Chun-shan,CHEN Xiao-yin,WANG De-jiu.Outcome of arthroscopic operation plus administration of qi-invigorating,kidney-supplementing,blood-activating decoction (益气补肾行血汤) on treatment of knee osteoarthritis[J].zhongguo gu shang / China J Orthop Trauma ,2005,18(8):449~451 |
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