刺激颈交感神经对家兔心脏功能活动变化的影响 |
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投稿时间:2002-09-23
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期刊信息:《中国骨伤》2003年,第16卷,第5期,第278-280页 |
DOI:doi:10.3969/j.issn.1003-0034.yyyy.nn.zzz |
基金项目: |
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中文摘要:
目的:探讨颈椎性类冠心病时颈交感神经受累对心脏功能的影响。
方法:健康家兔30只,显露双侧颈上、颈下交感神经节及心下神经,对各部分逐一给以电刺激,采用生理多导仪分别记录刺激后不同时间点的心电图ST段(ElectroccardiogramST,ECGST)、左心室内压(LeftVentriclePressure,LVP)、左心室内压最大上升速率(Developedpressure/Developedtimemax,Dp/Dtmax)的变化情况。
结果: 刺激颈上交感节后ECGST、LVP、Dp/Dtmax均无变化;刺激颈下交感节和心下神经后LVP、Dp/Dtmax值明显下降,ECG出现明显的STT改变。
结论:下位颈椎病变可能更易刺激交感神经而出现心肌缺血性改变,并可影响心肌收缩性能。 |
【关键词】颈椎病 交感神经 心功能 实验研究 |
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Influence of stimulating cervical sympathetic nerve on cardiac function in rabbits |
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ABSTRACT
Objective:To study effects of stimulating cervical sympathetic nerve on cardiac function so as to explore mechanism of cervical coronary heart diseases
Methods:In 30 rabbits,bilateral superior cervical ganglion(SCG),inferior cervical ganglion(ICG)and inferior cervical cardiac nerve(ICCN)were exposed and stimulated separately by electricity.Changes of index of cardiac function,such as Left ventricle pressure(LVP),developed pressure/developed time max (Dp/Dtmax)and ECG ST were recorded with physiologic instrument before and after stimulation.
Results:Stimulating SCG did not change LVP,Dp/Dtmax and ECG ST( P>0.05).After stimulating ICG and ICCN,LVP and Dp/Dtmax were descended obviously( P>0.01),besides ST segment and T wave depressed in ECG.With time,LVP,Dp/Dtmaxand ECG ST could ameliorate gradually.
Conclusion:Lesion occurred at inferior cervical vertebra was easy to stimulate sympathetic nerve,which could induce myocardial ischemia or abnormal cardiac contractility. |
KEY WORDS Cervical spondylosis Sympathetic nerve Cardiac function Experimental study |
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引用本文,请按以下格式著录参考文献: |
中文格式: | 齐越峰,张军,孙树椿,邵忠,庞伟.刺激颈交感神经对家兔心脏功能活动变化的影响[J].中国骨伤,2003,16(5):278~280 |
英文格式: | QI Yuefeng,ZHANG Jun,SUN Shuchun.Influence of stimulating cervical sympathetic nerve on cardiac function in rabbits[J].zhongguo gu shang / China J Orthop Trauma ,2003,16(5):278~280 |
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