刺激颈交感神经对家兔心脏功能活动变化的影响
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作者Author单位AddressE-Mail
齐越峰 QI Yuefeng 中国中医研究院骨伤科研究所,北京100700 Institute of Orthopaedics and Traumatology,China Academy of Traditional Chinese Medicine, Beijing 100700  
张军 ZHANG Jun 中国中医研究院骨伤科研究所,北京100700 Institute of Orthopaedics and Traumatology,China Academy of Traditional Chinese Medicine, Beijing 100700  
孙树椿 SUN Shuchun 中国中医研究院骨伤科研究所,北京100700 Institute of Orthopaedics and Traumatology,China Academy of Traditional Chinese Medicine, Beijing 100700  
邵忠 抚顺第三医院  
庞伟 辽阳市中心医院  
期刊信息:《中国骨伤》2003年,第16卷,第5期,第278-280页
DOI:doi:10.3969/j.issn.1003-0034.yyyy.nn.zzz
基金项目:
中文摘要:

目的:探讨颈椎性类冠心病时颈交感神经受累对心脏功能的影响。

方法:健康家兔30只,显露双侧颈上、颈下交感神经节及心下神经,对各部分逐一给以电刺激,采用生理多导仪分别记录刺激后不同时间点的心电图ST段(ElectroccardiogramST,ECGST)、左心室内压(LeftVentriclePressure,LVP)、左心室内压最大上升速率(Developedpressure/Developedtimemax,Dp/Dtmax)的变化情况。

结果: 刺激颈上交感节后ECGST、LVP、Dp/Dtmax均无变化;刺激颈下交感节和心下神经后LVP、Dp/Dtmax值明显下降,ECG出现明显的STT改变。

结论:下位颈椎病变可能更易刺激交感神经而出现心肌缺血性改变,并可影响心肌收缩性能。
【关键词】颈椎病  交感神经  心功能  实验研究
 
Influence of stimulating cervical sympathetic nerve on cardiac function in rabbits
ABSTRACT  

Objective:To study effects of stimulating cervical sympathetic nerve on cardiac function so as to explore mechanism of cervical coronary heart diseases

Methods:In 30 rabbits,bilateral superior cervical ganglion(SCG),inferior cervical ganglion(ICG)and inferior cervical cardiac nerve(ICCN)were exposed and stimulated separately by electricity.Changes of index of cardiac function,such as Left ventricle pressure(LVP),developed pressure/developed time max (Dp/Dtmax)and ECG ST were recorded with physiologic instrument before and after stimulation.

Results:Stimulating SCG did not change LVP,Dp/Dtmax and ECG ST( P>0.05).After stimulating ICG and ICCN,LVP and Dp/Dtmax were descended obviously( P>0.01),besides ST segment and T wave depressed in ECG.With time,LVP,Dp/Dtmaxand ECG ST could ameliorate gradually.

Conclusion:Lesion occurred at inferior cervical vertebra was easy to stimulate sympathetic nerve,which could induce myocardial ischemia or abnormal cardiac contractility.
KEY WORDS  Cervical spondylosis  Sympathetic nerve  Cardiac function  Experimental study
 
引用本文,请按以下格式著录参考文献:
中文格式:齐越峰,张军,孙树椿,邵忠,庞伟.刺激颈交感神经对家兔心脏功能活动变化的影响[J].中国骨伤,2003,16(5):278~280
英文格式:QI Yuefeng,ZHANG Jun,SUN Shuchun.Influence of stimulating cervical sympathetic nerve on cardiac function in rabbits[J].zhongguo gu shang / China J Orthop Trauma ,2003,16(5):278~280
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