非创伤性股骨头坏死与血浆脂蛋白的相关性研究
摘要点击次数: 2243   全文下载次数: 1200   投稿时间:2002-09-04    
作者Author单位AddressE-Mail
陈卫衡 CHEN Weiheng 中国中医研究院骨伤科研究所,北京100700 Institute of Orthopaedics and Traumatology,China Academy of Traditional Chinese Medicine BeiJing 100700  
林娜 LIN Na 中国中医研究院中药研究所  
郭效东 GUO Xiaodong 中国中医研究院骨伤科研究所,北京100700 Institute of Orthopaedics and Traumatology,China Academy of Traditional Chinese Medicine BeiJing 100700  
张洪美 中国中医研究院骨伤科研究所,北京100700 Institute of Orthopaedics and Traumatology,China Academy of Traditional Chinese Medicine BeiJing 100700  
孙钢 中国中医研究院骨伤科研究所,北京100700 Institute of Orthopaedics and Traumatology,China Academy of Traditional Chinese Medicine BeiJing 100700  
张磊 中国中医研究院骨伤科研究所,北京100700 Institute of Orthopaedics and Traumatology,China Academy of Traditional Chinese Medicine BeiJing 100700  
顾力军 中国中医研究院骨伤科研究所,北京100700 Institute of Orthopaedics and Traumatology,China Academy of Traditional Chinese Medicine BeiJing 100700  
赵铁军 中国中医研究院骨伤科研究所,北京100700 Institute of Orthopaedics and Traumatology,China Academy of Traditional Chinese Medicine BeiJing 100700  
期刊信息:《中国骨伤》2003年,第16卷,第2期,第69-70页
DOI:doi:10.3969/j.issn.1003-0034.yyyy.nn.zzz
基金项目:
中文摘要:

目的:研究非创伤性股骨头坏死与血浆脂质变化的相关性。

方法:研究对象120例,其中60例非创伤性股骨头坏死患者和60例正常人,采用奥林帕斯(Olypas)AU400全自动生化分析仪,检测总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白(HDL)、低密度脂蛋白(LDL)、载脂蛋白AI(ApoAI)、载脂蛋白B(ApoB)等指标。

结果:股骨头坏死组与正常对照组血浆脂质及载脂蛋水平比较,TC、TG、LDL、ApoB明显升高(P<0.05),HDL、ApoAI明显降低(P<0.05),ApoB/ApoAI比值显著升高(P<0.001).

结论:非创伤性股骨头坏死的发生和发展与血浆中的脂蛋白有密切关系,ApoB/ApoAI比值升高对估计非创伤性骨坏死的发生具有一定的临床意义。
【关键词】股骨头坏死  载脂蛋白B  载脂蛋白AI
 
A study on the relationship between plasma lipoprotein and non-traumatic necrosis of the femoral head
ABSTRACT  

Objective:To study the relationship between non-traumatic necrosis of the femoral head and blood plasma lipid

Methods:60 patients and 60 normal people were included in the study.Total cholesterol(TC),triglyceride(TG),high density lipoprotein(HDL),low density lipoprotein(LDL),apolipoprotein AI(ApoAI)and apolipoprotein B(ApoB) were determined with the automatism biochemical analysor of Olypas AU 400.

Results:Comparison between the patients and the normal controls showed that TC,TG,LDL and ApoB were significantly higher,(P<0.05),HDL and ApoAI were significantly lower in the patients than that in the normal control(P<0.05).ApoB/ApoAI ratio was also significantly higher in the patients than that in the normal control (P<0.001).

Conclusion:There was a significant association between change of lipoprotein and development of non-traumatic necrosis of the femoral head.A high ApoB/ApoAI ratio has clinical significance to estimate developing of non-traumatic osteonecrosis.
KEY WORDS  Femur head necrosis  Apo B  Apo AI
 
引用本文,请按以下格式著录参考文献:
中文格式:陈卫衡,林娜,郭效东,张洪美,孙钢,张磊,顾力军,赵铁军.非创伤性股骨头坏死与血浆脂蛋白的相关性研究[J].中国骨伤,2003,16(2):69~70
英文格式:CHEN Weiheng,LIN Na,GUO Xiaodong.A study on the relationship between plasma lipoprotein and non-traumatic necrosis of the femoral head[J].zhongguo gu shang / China J Orthop Trauma ,2003,16(2):69~70
阅读全文  下载  查看/发表评论  下载PDF阅读器
关闭




版权所有:《中国骨伤》杂志社京ICP备12048066号-2  版权声明
地址:北京市东直门内南小街甲16号,100700
电话:010-64089487 传真:010-64089792 Email:zggszz@sina.com

京公网安备 11010102004237号